Clomipramine User Reviews & Ratings (Page 2)

• helps...
• November 11, 2013

Anafranil (clomipramine) for Obsessive Compulsive Disorder "It has worked really well for my severe OCD, depression, anxiety and panic. It stabalizes my mood too. The side effects are awful for me, though. Sexual side effects (like my genitals are numb) and severe constipation are the two side effects that keep me from being on a more therapeutic dose. At 100mg, the side effects are bad. At 50mg I'm OK in terms of side effects, but the benefits are minimal. I will be going up to 75mg and see how that goes. In the past I had been on 150mg and then 200mg. I had never been happier. I think I may have been too happy rather than normal happy, though."

• Dont...
• Taken for 2 to 5 years
• July 21, 2020

For Panic Disorder "This medicine clomipramine saved my life from panic disorder. It took me six long years to find this medicine. I used to read all the reviews on this site hoping and dreaming I would one day have relief like so many on here. In fact some days it was my only way of keeping hope. This drug took 6-8 long months to take affect for me. It was slow progress out of hell, but everyday was better than the one before. Like the sun coming up you don't really notice it getting light out. Things that were impossible became possible. My thoughts were quieted and my mind could think about other things beside depression and anxiety. I have been on the drug for 6 years now. My depression and anxiety are gone. Like all gone! not diminished or tolerable but gone. My side effects are increased sweating and loose bowels. I am impacted by them but I would take the trade everyday and twice on Sunday : ) ."

• Eli
• Taken for 1 to 6 months
• January 10, 2019

Anafranil (clomipramine) for Obsessive Compulsive Disorder "This drug gave me my life back. After unsuccessfully being treated by various doses of Escitalopram and Paroxetine for nearly half a year my doctor prescribed Anafranil (Clomipramine is the generic name). What a difference it made! It takes longer to kick in, in my case precisely 4 weeks but it is well worth the long wait."

• Rod...
• April 20, 2013

For Depression "Side effects were really unpleasant but 2 months in have lessened to some degree - as an effective anti-depressant it is the best I have ever taken. I have been on just about every anti-depressant out over the last 20 years with nothing really working and worsening depression. I started to feel a lifting in mood almost immediately and now feel "normal" which is an awesome feeling. My social phobia/anxiety has almost disappeared too which is an added bonus. Wish I had been prescribed this years ago!"

• Scottyy
• Taken for 1 to 6 months
• February 7, 2013

Anafranil (clomipramine) for Obsessive Compulsive Disorder "Anafranil : Most likely the best medicine for obsessive compulsive disorder, overall. Yet each person has their own body chemistry/energy issues. Most people with OCD need about 100 to 200 mg at night. The key is to GRADUALLY go up in dose. This will give your body TIME to ADJUST to Anafranil. I am now up to 150mg, after 3 months and I am feeling much better. Much less OCD thoughts. Yes, sexual side effects...as with any OCD medicine. I used to take high dose Paxil for 8 years and it just wore out, OCD came back. I think I will try Anafranil 200 or 225 mgs, stay on it for a year, then see how I do as I try to wean down the dose to 50 or so."

• Tom...
• Taken for 1 to 6 months
• March 18, 2020

For Panic Disorder "Started at clomipramine at a dose 50mg daily for anxiety, Panic disorder, depression, and OCD. Slowly increased the dose by 50mg and currently taking 150mg at bedtime. This medication is an old one but don’t be fooled by new doctors and new medications. This medication has been a gift from god. At first I was afraid to start it after reading a lot of reviews about negative side effects. Only thing I’ve had is a little dry mouth. Other than that, depression is much better, panic attacks are way way down to almost nothing, and obsessive thoughts have dropped by about 90%. So overall this medication has been the best medication I’ve ever been on. Thankful for my older psychiatrist who had an idea my depression and panic was coming from mostly obsessive thoughts. I am so grateful to have been put on this med!!!"

• 95...
• Taken for 2 to 5 years
• June 15, 2023

Anafranil (clomipramine) for Obsessive Compulsive Disorder "This medicine has been a GAME CHANGER for me. I have struggled with OCD, panic, and anxiety all my life. This is the medicine that finally did the trick. My OCD is probably 95 percent better. It also has helped my panic attacks! Like other reviews state, it took about 4 weeks to work! I use GOOD RX to get it cheap too."

• Betty
• Taken for 10 years or more
• July 31, 2018

Anafranil (clomipramine) for Depression "I have been using Anafranil (clomipramine) for more than 10 years. It has done wonders. I only take 25mg, but that is enough for my OCD. I can take more if I want but don't want any side effects. Anafranil did what no other antidepressant could do. It is an older drug but for me it's better."

• Cheesus
• July 13, 2016

Anafranil (clomipramine) for Depression "I've been taking this medication for major depression for 14 years now. 17 years ago I was given big doses of steroids due to problems resulting from back surgery. Those high doses of steroids pushed me into major depression. After 3 1/2 years of trying to find a medication that worked for me, I was prescribed Anafranil. Within two days I was seeing positive results. Within a year of taking Anafranil I was free of depression. I've been taking Anafranil ever since - somewhat afraid to stop. There are many side effects - that I often get tired of - but they pale compared to the relief I received from this medication. It is the most serotonergic of the tricyclics and I feel should be more widely tried for major depression."

• Anonymous
• Taken for 6 months to 1 year
• October 30, 2015

Anafranil (clomipramine) for Obsessive Compulsive Disorder "This medicine saved my teenager from horrible OCD. 200mg at bedtime, dry mouth is the only side effect. Every once in awhile he will have an episode, but I am able to talk him through it. He tried every med, this was the only one that worked."

• Best...
• Taken for 1 to 6 months
• September 20, 2023

Anafranil (clomipramine) for Obsessive Compulsive Disorder "After two failed SSRIs (Lexapro and Zoloft), I'm so happy I tried Anafranil. This is the best medication, and I wish doctors would prescribe this before SSRIs. I had little to no side effects when I first started taking it. I take it at night because it does cause drowsiness. I've been taking it for 3 months but felt the effects after 2 weeks! I have little to no intrusive thoughts from my OCD. There may be some days where my anxiety is not its best, but they're manageable, and I have this medication to thank. Please give this a try! It's an old medication, but it's so worth it, especially if SSRIs are not working for you!"

• Batch
• July 17, 2013

For Depression "This medicine saved my life. I have now been on it for 12 years for anxiety and depression. I tried a whole slew of SSRI's over a three year period with minimal success prior to clomipramine. A week after starting clomipramine I started to feel better but had some major side effects (dry mouth, constipation and later weight gain). With the SSRI's I had no or minimal side effects. I thought maybe these side effects mean the medicine is working. The side effects continued for about 5-6 weeks but damn I started to feel like my old self. I gained about 15 pounds in the first 8 months but I didn't really care because I could live again and enjoy my family and friends. The weight all came off after about a year with exercise and eating right. Awesome!"

• Pregn...
• Taken for 1 to 6 months
• September 18, 2018

Anafranil (clomipramine) for Obsessive Compulsive Disorder "So I’ve been taking Anafranil for about 8 weeks now. I started at 25 mg and now I’m at 100 mg.. gradually moving up as time goes on. I didn’t have OCD until I got pregnant with my daughter and started having horrible intrusive thoughts that made me depressed. I’ve tried Zoloft, Lexapro, Paxil and now this one. This has worked for the most part but it hasn’t “cured” anything. I still have my days but out of all the medication I’ve tried this has been the best. Thankful overall for this medication. Give it a try and try to remember these kind of meds take time to work. Sending positive energy to you all!"

• Aud
• Taken for 1 to 6 months
• October 21, 2012

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I have/had severe OCD. I have been on citalopram, Zoloft and Prozac. I was started on 150mg Anafranil and within what seemed no time at all my OCD disappeared. Prozac did work for OCD but not on clinical depression. I am now on 200mg. I have had no weight gain (nor did I have on SSRIs). I get a dry mouth sometimes but counteract this with a anti dry mouth toothpaste."

• Geger...
• Taken for 6 months to 1 year
• March 3, 2021

Anafranil (clomipramine) for Depression "I had tried escilatopram (Scippa) and vortioxetine (Trintellix) before, practically both were ineffective. Anafranil has been a miracle for me, within a month it reduced my severe suffering very effectively, and made me much better for 90% of my time. And it was reached quickly with very small dosage: 20 mg a day. Minor side effects occurred during the first couple of weeks, the most unpleasant was the dry mouth and reduced libido, but it bounced back within weaks."

• accn
• Taken for 1 to 2 years
• October 27, 2019

Anafranil (clomipramine) for Obsessive Compulsive Disorder "Have had depression since a young teen and started to have OCD thoughts and compulsions at about 15. Tried several anti depressants which always helped (apart from Prozac) with my mood but never with the OCD. Psychiatrist said that anafranil was basically my last hope and I have been on it now for nearly 2 years. 25mg twice a day. My obsessive thoughts are practically gone and the anxiety around my compulsions is so mild. Never felt sick or sleepy starting on them either. Very hard to find this medication anywhere around where I live in Ireland. Always has to be ordered in advance."

• LynnC...
• June 12, 2017

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I've only been on this medicine for 3 weeks but it's already doing wonders. I still have "the thoughts" but they don't "take root" like they normally do. They come and go throughout the day rather than being ALL I can think about. My Dr is slowly upping my dose to 100mg, and I'm currently on 75mg and already seeing benefits. It takes a few weeks to REALLY start working so if you are on week 1 or 2 give it some time. It's been amazing at helping me fight my compulsions. It makes me really believe OCD is a MEDICAL issue. The morning is still the worst for me, when all my thoughts first hit me, but since I've started this drug, I can make it through the day so, so much easier."

• Abigail
• Taken for 1 to 6 months
• October 20, 2020

For Obsessive Compulsive Disorder "I started clomipramine due to a sudden rise in panic attacks and severe OCD. (which was super strange because I have only had a couple panic attacks my entire life) My doctor said this might help my symptoms and I could not be any happier. It has taken away my OCD symptoms about 90%. This is insane. I can't believe I am even typing this. I have had severe, AWFUL, OCD since my childhood and now all of my intrusive thoughts are gone. If I do have them they are fleeting and aren't debilitating like they used to be. At the beginning I had some side effects like extreme dizziness and lack of appetite- but now I feel better and they are lessening. I am confident that this medication saved my life."

• Thank...
• Taken for 1 to 6 months
• June 10, 2016

Anafranil (clomipramine) for Panic Disorder "I had a break up and was suffering extreme anxiety and depression. I was not functioning at work, in life and suffered for several months. I was getting worse and worse, not sleeping and finally broke down and decided to take an anti depressant. After about 4 days something changed a little within a two weeks my anxiety went away and I began sleeping again as well. I weaned off of the ativan I was taking and this drug saved my life. I probably would have been hospitalized if I didn't go on it. Side effects, sweating (a lot), constipation, and of course ejaculatory issues but still could have sex for my partner. This side effects were easy to deal with when compared to my anxiety. Save my life!!!"

• Iml
• Taken for 1 to 6 months
• December 17, 2018

For Obsessive Compulsive Disorder "I don't even know where to start. This medication was the breakthrough for me. I had tried so many medications over a year and a half before my doctor put me on this. I was skeptical at first, started off on a small dose, the nausea and headaches were not too terrible. The first few weeks my obsessions got worse but once I was at 100mg I felt a small breakthrough and a small ease of my symptoms. I had even greater results at 150mg. I'm now at 200mg working my way up to 300mg but honestly this is the best I have felt in years and for the first time I feel like I can enjoy my life and breathe without the constant obsessions and compulsions. I'm not saying this will work for you but do not give up, I thought I was hopeless and medications would never work for me until I finally got on this. There is light at the end of the tunnel and you deserve to have this same feeling!"

• Living...
• Taken for 1 to 2 years
• March 2, 2017

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I have been taking Anafranil 100mg for a year now and it has changed my life. I have battled with OCD, severe anxiety, panic disorders and intrusive thoughts since I was young. While trying different drugs finally at the age of 40 one drug works for me and this is it. I still have the "thoughts" but instead of obsessing over them they pass by like moving cars. The side effects are bothersome dealing with constipation, bloating, sweating, insomnia, twitches. I don't believe I can ever function without this medication and instead maybe lower my dosage to see if it reduces the side effects."

• Anonymous
• October 4, 2017

Anafranil (clomipramine) for Obsessive Compulsive Disorder "This medication is absolutely life changing. After years of suffering anxiety OCD with mostly intrusive racing thoughts that caused insomnia this medication was a miracle!! I had tried so many failed medications and therapies that I became hopeless. I was prescribed this medication after being hospitalized and have never been back that was over 2 years ago. It took 4 weeks to work please give it time. I feel like I have my life back!"

• Bobby...
• Taken for 10 years or more
• August 20, 2019

For Obsessive Compulsive Disorder "Anafranil or Clomipramine has completely changed my life. I have been taking it for over 25 years (I'm 51) and wish I started it 25 years sooner! It started to ease my OCD symptoms almost immediately. I was first given several SSRIs and could not take the side effects - they made my OCD much worse. Don't settle for the medication of the month or what your doc has seen work in the past. Everyone's brain chemistry is different and just because Clomipramine is old does not mean it's ineffective. I also have Adult ADD. My meds for that have not proven to cause any problems with the Clomipramine. Best wishes to all sufferers."

• Ela
• November 28, 2015

For Depression "I have tried everything the only one that really helped me after I lost hope The doctors don't give it to you because its an old medication, the patent is over and the big pharmaceutical companys don't make any money. But believe me it is the best give it 2 month chance."

• nasca...
• January 1, 2012

For Panic Disorder "I suffered with panic attacks, depression and obsessive compulsive disorder for many years. Finally, I tried Anafranil (only 25 mg) and it was my miracle. I have been on it for almost 30 years. I have not suffered any side effects and have not had to increase the dosage. I HIGHLY recommend suggesting this medicine to your doctor if you have any of the problems. This literally saved my life."