Canagliflozin and Weight Loss: What Users Say

• GCD...
• Taken for 1 to 6 months
• July 7, 2014

For Type 2 Diabetes "Diagnosed with type 2 diabetes in 1996, I've been prescribed the usual medications with not much success. Five months ago, my doctor (of 32 years) prescribed Invokana 100 mg. Mind you, I have always eaten very well and choose my food wisely. However, since starting Invokana, I have lost 46 pounds in 4 months and went from a 44 waist to a 36, and I'm still losing weight. My A1C went from 11.3 to 8.0 in the first three months. My doctor challenged me and wants to see a 7.0 for my 6-month checkup. I believe I will hit this goal and be below 200 lbs for the first time in decades. Invokana works, and for two other construction workers I work with, who also lost a lot of weight. The only downside I deal with is going to the bathroom twice as much as before."

• Ken...
• November 19, 2014

For Type 2 Diabetes "Started Invokana 100 mg about a month ago. Only side effect is some yeast infection, but not bad. I had been on 100 units of Levemir and 100 units Novolog with blood sugars still in the 200-400 range at times and fasting blood sugars never below 200 range. Now, my fasting blood sugars are 120-140 range and my insulin has been decreased to 50 units of Levemir and 30 units of Novolog. So, doctor has increased the Invokana to 300 mg. Hoping to be off Insulin soon. Oh, and I have lost 6 pounds in the process. The key to this medication is to DRINK plenty of water to stay hydrated, have your kidney functions checked at least twice a year and monitor for any side effects."

• Dan...
• July 18, 2015

For Type 2 Diabetes "Been on Invokana 300mg once a day, taken prior to breakfast, for 8 weeks. Third box starts today. Slight burning around head of penis week 1 & 2, wash more, gone. Thirst all day, most drink a lot, upward of 6-8 bottles per day, peeing a lot, 9 times a day. Good thing as you must flush kidneys. Weight loss, wow. Lost 31 pounds in 8 weeks and yes, that's without exercise or change in diet. Not sure if that's all good, but wow A1c 10.9 - 8.0 down to 7.5 - 6.2 on average. Still tired a lot around 2 pm afternoon. Age 52."

• Dia...
• Taken for 6 months to 1 year
• October 9, 2015

For Type 2 Diabetes "I have been type 2 diabetic for 20 years - tried the diet and exercise, then the metformin (never helped). Went on Lantus insulin and A1C gradually just kept going up, and was up to 70 units of insulin and Janumet 2x daily. Doctor said to either try Invokana or insulin shots multiple times a day. Gave it a try - the most horrible yeast infections ever, but lost 6 lbs in 10 days. Decided to stick with it, and now almost a year later lost 35 lbs and feel great, and A1C is down to 6, and I dropped my insulin down to 25 units! I love this drug! I stuck through the yeast infections, and now that the sugar levels are down, I don't get the infections as often! I am thinner than I was in high school!"

• Sny...
• December 1, 2013

For Type 2 Diabetes "I, too, have had great results with this medication. It's almost too good to be true. Some weight loss, my readings dropped significantly. I now wonder if it is helping my psoriasis. As after many, many years, it has disappeared from my right leg altogether."

• Mic...
• Taken for 1 to 6 months
• August 21, 2020

For Type 2 Diabetes "Was put on Invokana in March of 2016. Previously had an A1c of 10.6. Did a good job in knocking down my high numbers but was losing a lot of weight, but next A1c was 6.4. Became sicker and sicker, losing more weight. Ended up in the hospital getting dialysis with renal failure. They immediately suspended Invokana. Invokana almost finished me off!"

• Reb...
• June 17, 2015

For Type 2 Diabetes "Started taking 100 mg daily at night, numbers came down in a week. Went to see the doctor in a month, he was happy, then he prescribed 300 mg daily. Soon after taking this dosage, I began to experience an itching on my penis, and it was driving me crazy. I also experienced more frequent urination along with an insatiable thirst. I was about to schedule an appointment with my urologist until I Googled 'side effects of Invokana.' The itching wouldn't stop, I didn't know that there were these side effects from this medication, and even though it helped bring down my sugar levels, I really don't think it's worth the other problems it presents. I too have experienced weight loss. It is a good medicine, but the side effects aren't worth it. Sorry."

• Hol...
• January 10, 2019

For Type 2 Diabetes "'I have been on 100 mg Invokana for a few years now. When I started taking it, I experienced a small weight loss and it appeared to lower my A1C. One month in, I stopped having periods, experienced occasional yeast infections, and vaginal itching. Over the years, the side effects have grown more intense and frequent. It's miserable! Within the last two weeks, I have started having discomfort and a burning feeling in my right foot. I contacted my doctor's office to inquire how to wean myself off this medication, but I was told I needed to make an appointment to 'discuss my options.' I've had enough of the side effects! I am taking myself off this medication whether my PCP agrees or not. Considering my experience with side effects, reading other reviews from users, I will not be taking it again."

• Sea...
• Taken for 6 months to 1 year
• December 4, 2015

For Type 2 Diabetes "I went on this drug on the advice of my physician. It was horrible, I lost 8 lbs, but my A1C went up from 6.9 to over an 8. My cholesterol went from good to bad, and I was always thirsty, which means I stayed looking for bathrooms. My endurance and circulation got worse too. As soon as I was taken off, my numbers got better. The weight came back, but my overall numbers got better. Now I'm off with better numbers, but I'm still trying to get my endurance and circulation better. I still get winded easily, but I'm working on that. I suggest staying away from this medication. I changed physicians, and the new one said he doesn't like what he's seen and that he feels that this medication set me back."

• Ale...
• October 9, 2016

For Type 2 Diabetes "I have been taking Invokana for about 5 months, and I feel great! My A1C went from 9.8 to 7.4 in 3 months. The only side effect I have noticed is some weight loss. But the weight loss stopped. It does make me really thirsty, a small price to pay for controlled blood sugar levels."

• sue...
• Taken for 1 to 6 months
• January 22, 2015

For Type 2 Diabetes "I've been on this medicine for a little over 2 months, no bad side effects to report, unless you call loss of appetite and a loss of 20 lbs bad. Blood pressure has lowered from 160/89 to 118/76."

• Anonymous
• Taken for 1 to 6 months
• February 16, 2015

For Type 2 Diabetes "I have been taking Invokana for 5 months, weight loss and lower blood pressure is a good side effect."