Canagliflozin and Tiredness: What Users Say

• Dan...
• July 18, 2015

For Type 2 Diabetes "Been on Invokana 300mg once a day, taken prior to breakfast, for 8 weeks. Third box starts today. Slight burning around head of penis week 1 & 2, wash more, gone. Thirst all day, most drink a lot, upward of 6-8 bottles per day, peeing a lot, 9 times a day. Good thing as you must flush kidneys. Weight loss, wow. Lost 31 pounds in 8 weeks and yes, that's without exercise or change in diet. Not sure if that's all good, but wow A1c 10.9 - 8.0 down to 7.5 - 6.2 on average. Still tired a lot around 2 pm afternoon. Age 52."

• Cub...
• Taken for 1 to 2 years
• November 10, 2014

For Type 2 Diabetes "I have been on Invokana since September 2013, so a little over a year. I have experienced hair loss, tiredness, and yeast infections. I talked to my doctor about the hair loss, which I experienced for over a year. He has upped my Metformin to the maximum dosage. My hair has stopped falling out. I am also using Rosemary essential oil to help with hair loss, and probiotics for the yeast infection. I have had amazing results with this medication in regards to blood sugar control. My A1C went from 12.3 to 7.1. I have never had such control. As a benefit, I have lost over the course of a year 34 pounds. I feel that the benefits outweigh the side effects."

• and...
• June 21, 2016

For Type 2 Diabetes "I've been on Invokana for two years. I never lost weight on it; however, my A1c had finally gone to normal after 20 years of being a diabetic. However, I had to stop taking it today after I put two and two together about the symptoms I am having: hair loss, severe muscle and joint pain, severe muscle cramps and contractions of legs at night that I would literally cry, and hands cramping and contracting day and night; frequency and urgency to urinate (I unknowingly peed in bed several times and peed on myself during the day uncontrollably); brain fog, severe tiredness; constant yeast infection; bladder infections; constant thirst; and eye infections when I never had them before. This medication needs to go off the market. Pray for me!"

• Ash...
• Taken for less than 1 month
• March 19, 2014

For Type 2 Diabetes "I have been a type one diabetic for 28 years now, and I'm 33 years old. I have been on a pump for 11 years now, with sugars either low 30s or over 600... never perfect. My endo even prefers my sugars in the 200s, since I'm so used to it. But here lately, I'm over the sick feeling, being tired, and sugars being sky high. My new primary physician I started going to 3 weeks ago mentioned this pill, so last Monday he gave me a week's sample and a prescription. Sunday night my sugar was 571, Monday morning before my doctor's appointment it was 221. I took this pill when I got out of the doctor’s office, and my sugar has been below 100 ever since. I have energy and feel great all in three days. I'm going to have to adjust my pump settings for lower doses. I love it."

• Cat...
• February 21, 2015

For Type 2 Diabetes "Have only taken the product for 2 days, but have felt tired. My appetite has been less than usual. I am glad with the loss of appetite. But I am in hope that the tiredness will diminish once I have been taking the medication for a while."

• Sou...
• September 3, 2015

For Type 2 Diabetes "The general side effects of dehydration and urination aside, those were not my problem. Fatigue was the issue. I was on 100 mg to start and noticed after six weeks a decrease in mental acuity -- missing things I might not otherwise, more forgetful. My dose was increased to 300 mg and all I wanted to do was sleep. Went back down to 100 mg, but the exhaustion continues. Time to try something else."

• Sco...
• Taken for 1 to 2 years
• July 25, 2015

For Type 2 Diabetes "A1c 13 a year ago. Taking 300 mg Invokana alongside 2000 mg metformin and 50 u lantus once daily. A1c made it to 7.0. Very happy now. Lantus alone and lantus plus metformin did not help enough over the last ten years. Thirsty and sometimes tired (water and caffeine counter this). Also taking a tiny dose of lisinopril to protect kidneys. No other side effects (never encountered any urinary issues)."

• Anonymous
• November 2, 2016

For Type 2 Diabetes "Put on meds 300 mg summer of 2016 after being on 100 mg Januvia since 2007. Have all the side effects, I told the doctor who said it's normal. Do have kidney disease that we monitor. Issue is I feel like I'm going crazy, brain fog, very, very tired, anxiety high, don't trust my judgment, my OCD has come back big time, know what I'm thinking about, just can't think of the right words, know what I want to say but comes out different, paranoid, insomnia. I sleep about 12 hours a day, don't have energy, hot flashes. Used to be a very active person. Don't want to do anything or be bothered by anyone, my life has really been altered. Was just wondering if anyone else experienced this too."

• Bob...
• Taken for 1 to 6 months
• May 6, 2016

For Type 2 Diabetes "I took Invokana for about 3 weeks at 100 mg. Within 2 weeks, I had a yeast infection and generally had an ill body feeling. I was jumped up to 200 mg, and in approx 2 weeks, I had swelling in both armpits, legs, and pains all over my body. I stopped and started this drug 3 times, and every time I tried to, the same swelling in my armpits and arms. We had no idea if it was the drug or underlying health conditions. Due to swelling in the armpit and pains, my doctor screened me for cancer, as it runs in the family. All STDs and meningitis all came back negative. Every time I stopped this medication, I felt better. Felt so lethargic and pain in my arms and back. Will never take it again. Ever!!!!!"

• Anonymous
• Taken for less than 1 month
• August 6, 2017

For Type 2 Diabetes "I have been a T2 diabetic for 10 years. I started Invokana 2 days ago, and it has been absolutely horrible. I have never felt so bad in my life. I am unable to perform my job, having to leave work early because of the feeling of just being extremely tired. I have been in bed these last two days more than I would like. I have been urinating every 15 to 20 minutes all day and night and have noticed a smell in my urine that wasn't there before. This medication needs to be pulled off the market."

• Gra...
• Taken for 1 to 6 months
• October 19, 2016

For Type 2 Diabetes "Started off on this drug August 2 of this year at 100 mg. Within 10 days, was being treated for severe dehydration. Increased fluid intake, and dosage was upped to 300 mg. Now in October, glucose numbers are down to normal, have lost 38 lbs, but side effects are unbearable. Severe itching, leg and hand cramps all night long, and yeast infections are too frequent. Tired all the time. I agree it works, but at what cost? Miserable diabetic! I'm not going to take it anymore. I'm done fighting!"

• Igo...
• Taken for 6 months to 1 year
• November 7, 2016

For Type 2 Diabetes "Med helped control blood sugars a little, but with awful side effects. Was taking 100 mg, never increased to the reco 300 mg, couldn't do it as I felt so awful on the 100 mg. Side effects were extreme tiredness and thirst, nausea, increase in HDL and triglycerides. After a few months, started losing my hair, probably lost 50% volume, and getting terrible leg cramps in calves at night would wake me up several times each and every night. Severe stabbing pains mid/lower back, and the brain fog was terrible. Quit drug!! Spoke to pharmacist, he had multiple people coming in saying, 'Get me off this drug, it's killing me' - which is how I felt! Drug company paid for the drug even though my insurance would have paid for it, pharmacist thought this was odd."

• Che...
• Taken for less than 1 month
• July 6, 2018

For Type 2 Diabetes "So my doctors put me on Invokana to bring down my sugars as I have always been in the 200 plus morning and night. Well, it worked to drop my sugar. But now I am tired, and on edge (nerves) feels like anxiety - something I cannot handle. Though my blood sugar dropped, I cannot handle this."

• Bre...
• Taken for less than 1 month
• March 12, 2017

For Type 2 Diabetes "T2. I have been on Metformin 1000 for several years, and with diet and monitoring BS levels, have managed well. Recently, I have struggled with numbers and decided to give in to additional help in the management of numbers. I started with a 10-day sample of Invokana 100 and did well. Felt fine, no real issues of concern. Even thirst and restroom visits didn't really increase. Then started the 300 10-day sample, and again no real noticeable issues. Requested a prescription, and now, 10 days later, I can barely stay awake. I have always been a 5-6 hour-a-day sleeper, and now I am so exhausted I could easily sleep 10-12 hours a day. Decided to try splitting the pill to see if anything changes in my sleepiness before requesting to go back to the 100."

• lin...
• Taken for 1 to 6 months
• July 5, 2017

For Type 2 Diabetes "I have been using Invokana 100 mg for the past two months. My blood sugar levels have gone down to normal. I lost 10 pounds of weight. Sometimes I feel dizziness and extremely tired. This medication is not as effective as in the initial days. But still, I would recommend this, as I have not faced any major side effects. 50% of the medicine cost is paid by my insurance, $15 from my pocket, and the rest is paid by the Invokana savings card."

• LP1...
• Taken for 1 to 6 months
• July 26, 2015

For Type 2 Diabetes "My side effects are: weight gain, vaginal yeast infection, tired, itching skin, increased hunger, dry mouth, cloudy urine, increased thirst, breathing difficulty, sweats, 2 months."