Canagliflozin and Fatigue: What Users Say

• Anonymous
• Taken for less than 1 month
• October 19, 2014

For Type 2 Diabetes "I have had reactions to three previous medications. I was hopeful with this one because it works differently. Started on 100 mg. By day 7, I was starting to feel very fatigued 2 hours after taking the pill. Noticed a decrease in urination and blurred vision. Symptoms worsened the next couple of days. Lasted 10 days. Guess I go back to my almost carb-free diet."

• Pga...
• Taken for 1 to 6 months
• September 21, 2019

For Type 2 Diabetes "Started on Invokana three months ago. Noticed slight headache after taking it, increased urination, lowered A1c. Slowly, over a period of time, two months, I noticed increasing fatigue, weakness. Eventually, this affected daily activity, I can’t even begin to describe how exhausted I became. Stopped taking the drug, and within two days, strength and stamina have begun to increase."

• Sou...
• September 3, 2015

For Type 2 Diabetes "The general side effects of dehydration and urination aside, those were not my problem. Fatigue was the issue. I was on 100 mg to start and noticed after six weeks a decrease in mental acuity -- missing things I might not otherwise, more forgetful. My dose was increased to 300 mg and all I wanted to do was sleep. Went back down to 100 mg, but the exhaustion continues. Time to try something else."

• Wea...
• Taken for less than 1 month
• June 21, 2016

For Type 2 Diabetes "Within 12 days, 100 mg brought my sugar down 40 pts. HOWEVER, it did a number on my blood pressure. I have excellent blood pressure, on the lower end of normal, and this dropped it down to the point I could barely function. Fatigue so bad I had to stop driving after 15 miles because I was falling asleep at the wheel. Going up the 3 flights of stairs to my apt felt like climbing Mt. Everest. Constant dizziness, wooziness, the floor felt like it was moving when I'd bend down. Weird tunnel vision effect like what happens when you know you're gonna faint. It took 2 full days for all those side effects to clear after I quit taking it. I suffered 12 days thinking I'd get used to it, but it just kept getting worse. Beware low BP side effects with it."

• Tam...
• Taken for 2 to 5 years
• April 17, 2017

For Type 2 Diabetes "At first, I liked it. My endocrinologist was waiting for it to be approved and available, so put me on it once it was. It lowered my blood sugar and my blood pressure. I did not lose weight as some do (which I suspect is mostly water weight from urinating more). I had to stop my blood pressure medicine because I felt I was bottoming out with both meds (Invokana was lowering my blood pressure too). But now that I have been taking Invokana, since it was available, I just recently stopped it due to not being able to handle the side effects anymore. I feel so fatigued all the time. My muscles ache once I get to the top of my stairs. I am out of breath and feel like I have run a marathon. My chest would feel tight and just felt faint all the time when doing anything! Add life's stresses (job) to that, and it made me so miserable! And, I have been working out 4 days a week since January! It is so frustrating. I am also on week 4 of a nothing but veggie and some fruit smoothies (no meat, wheat, and only dairy is whole-fat Greek yogurt). So I figured since I was having to watch my blood sugars more closely, since they were lower with this new eating plan, now was a good time to quit the Invokana. I am hoping within a week I might feel like my old self again. Due to doing everything I can to help my diabetes, and I still felt bad, I knew it had to be my Invokana. The only other med I take is Lantus SolarStar. I started to get worried about long-term effects of Invokana, especially since I was doing what anyone with health issues should do (exercise and eat super healthy), and still felt fatigued, I decided to do more research online and have found many others with my same and worse side effects. Many complain of constant yeast infections (both women and men), hair loss, swelling of lymph nodes to where they did STD tests and cancer screening, shortness of breath, fatigue, urinary tract infections, bladder infections, kidney issues (some really bad). I got scared reading so many bad reviews. I don't want to end up with major kidney problems! So I am going to do what every Type II diabetic should do, and actually eat healthy and exercise! We are switching to organic foods and plan to continue drinking these green smoothies for 2 meals a day and have a reasonable dinner. We need to lose weight anyway. That will ensure we get tons of veggies and fruits and so much nutrition that we would otherwise be deficient in. We keep track of all our calories to ensure we get enough protein and healthy fat, etc. I also take some supplements, superfoods, and vitamins made with whole food. We are going to stop all soda, sugar, artificial sweeteners, and pre-made and highly processed foods, as best we can... it will be a process, lol. I am so mad at all that is put in our food, I can't believe it is legal! Most chronic type diseases are due to inflammation in the body and what we put in our bodies. Healthy in, healthy out. Crap in, crap out. You are what you eat. Stop putting chemicals and toxins in your body. Stop eating food that is not raised/cultivated naturally healthy. Eat whole food and 'clean' foods. Cure yourself with Nature's Nutrition! Good luck to you all! :D"

• Dr ...
• Taken for 6 months to 1 year
• September 4, 2015

For Type 2 Diabetes "This med is amazing!! Absolutely the best medication developed! Was at 11 on HBA1C on Metformin and Glimepiride. Invokana was added and amazing, I've run consistently at 7.0!! Now I take 2,000 mg Metformin, 1,000 mg BID, and Glimepiride 4 mg a day with Invokana increasing to 300 a day. If you've got problems, why delay any longer? Insist on Invokana immediately! To the guy that says he had general malaise and fatigue, I'd get your CBC checked. Very doubtful it's from Invokana."

• Dr ...
• Taken for 6 months to 1 year
• September 4, 2015

For Type 2 Diabetes "This med is amazing!! Absolutely the best medication developed! Was at 11 on HBA1C on Metformin and Glimepiride. Invokana was added and amazing, I've run consistently at 7.0!! Now I take 2,000 mg Metformin, 1,000 mg BID, and Glimepiride 4 mg a day with Invokana increasing to 300 a day. If you've got problems, why delay any longer? Insist on Invokana immediately! To the guy that says he had general malaise and fatigue, I'd get your CBC checked. Very doubtful it's from Invokana."

• Jes...
• Taken for 2 to 5 years
• June 11, 2021

For Type 2 Diabetes "I have been on Invokana for 3.5 years. In the beginning, I had horrid yeast infections, and my PCP had me visit my GYN, who put me on a 6-month dose of Diflucan to reset my body's pH, and I haven't had issues in years. I also had the muscle cramps and fatigue but realized it was dehydration and resolved it by drinking more water. My last A1C was 5.1, so I asked my PCP if I could go from 300 mg to 100 mg, and she agreed to a 3-month trial. I'm starting my 3rd month of 100 mg, and next month I get my A1C checked, and I'm hoping to stay on 100 mg. I'm down 110 lbs. I'm hoping if all goes well on the 100 mg, then an additional 70 lbs down, I can go off medication completely."

• vij...
• Taken for 1 to 6 months
• August 13, 2017

For Type 2 Diabetes "I have BP and Diabetes Type 2 for a long time. I take Metapro XL 1, Minipress 5 mg 1 for BP, and Januvia 100 mg 1 tab, Metformin 1 gm twice, and Invokana 100 mg before breakfast for Diabetes. Gradually, I am losing weight and feel fatigue during the day. In the last 3 months since taking Invokana, my fasting sugar is 117 and PP is 142. I have, however, lost 6 kg. Please advise remedy."

• Rbh...
• Taken for less than 1 month
• July 7, 2013

For Type 2 Diabetes "This medicine made me feel very sick. Extreme fatigue and dehydration."