Bupropion / naltrexone and Vomiting: What Users Say (Page 2)

• Jac...
• Taken for 1 to 6 months
• March 6, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "So I have been taking these for 1 and a half months, 4 pills a day. The Good: I have to force myself to eat or I can go all day without eating. I have lost 20 lbs. Contrave has helped curb my alcohol addiction, which is helping with the weight loss. I have no trouble sleeping. The Bad: I've had to throw up a couple of times. I've had a few tummy aches, a little constipation, I have had a few headaches, but nothing too bad. Once I went up to 4 pills a day, I've noticed that I am a little jittery, more depressed, anxious, and for the last few days my chest has been hurting and I got a couple of sharp pains in my heart. So I'm dropping down to 3 pills a day. I don't want to stop taking the pills because they do work. If I don't feel any better, I will drop to 2 pills a day. I feel like I'm dehydrated all day! But this has made me have to drink a lot more water, which is also helping with the weight loss. I am really happy that I'm sleeping well during the night, I do get tired still during the day and have been taking naps."

• Mar...
• October 22, 2019

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am a 34-year-old female, 183 lbs and a BMI of 28. I wonder if my doc should have even prescribed this to me... I used this drug for 3 days and had a horrible experience. My side effects were stomach cramping, severe headache, and violent vomiting. The brain fog many speak of turned into severe headaches and nausea turned into violent bouts of vomiting. To the point that I thought I would have to be admitted to the hospital. Also, I was unaware this contains an opiate blocker, naltrexone, and the ingredient bupropion, used to treat depression, the neurological effects were also quite concerning. I had spasms in my muscles and joints, like small surges of electric shock. I had a really scary experience and do not recommend this to anyone unless they have done thorough research on how the ingredients can affect them. I have been off of this drug for 2 days and still feel unwell."

• KDJ...
• May 25, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I started Contrave May 21, 2015, and so far have lost 6 pounds. I haven't had any nausea or vomiting, but the diarrhea is a bit annoying. It's totally bearable though. The reason I started this drug is because I gained thirty pounds ever since the love of my life passed, and I can honestly say I feel like it's saving my life. The bupropion gives me life, but I don't know if it's the naltrexone that makes me a little sleepy after taking it. I'm a 20-year-old male, 6 ft and weigh 200 pounds, and I can honestly say I'm feeling more and more confident as the days pass! Insurance companies don't know much about it, so get that savings card!"

• Fee...
• Taken for less than 1 month
• September 6, 2016

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I began taking this medication Sunday morning. About 2 hours after I took the first pill, I began having painful stomach cramps that began near my diaphragm and moved all over my stomach. I also started in with diarrhea. Monday, after taking it, I still had the diarrhea but was also feeling very queasy. This morning, I took the last pill I will ever take. I still had the diarrhea, but I also had an unimaginably painful migraine and started vomiting uncontrollably. It was so bad that I even aspirated it a couple of times because I couldn't stop long enough to take a breath. I was in the ER from 10 am to 3 pm on nausea and pain meds. I have never felt like I was going to die until today. Please be careful while on this medication."

• Sus...
• Taken for less than 1 month
• September 2, 2022

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I really wanted to stay on this. I stopped after three days. Nausea, vomiting, fuzzy head, loss of balance, and dizzy. Just couldn’t do it at my age (74). Can’t afford to fall! Most can work through it."

• ben...
• Taken for less than 1 month
• January 21, 2016

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am 5'2", 268 lbs. I started Contrave on 01/19/2016. The first day, I did vomit maybe 30 minutes to an hour after taking it. But after reading some posts, a lot of people were stating to take it in the middle of a meal to avoid nausea. THIS WORKS! I haven't had any other side effects so far. I noticed that I am not as hungry or have the urge to just snack. Right now, I take one pill a day and will be starting 2 pills on Monday. I also started exercising 30 minutes to an hour a day. So far, so good. My insurance did not cover the drug, but my doctor gave me a discount card. I paid $70 for a month's supply. I will keep updating my results."

• den...
• Taken for less than 1 month
• December 13, 2021

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I got on this pill 5 days ago, and it has been a terrible experience. My GP prescribed it for my binge eating problem and had to stop using Lexapro, as it may cause seizures if two pills are consumed together. For the last 5 days, I have been nauseous, vomiting, feeling extremely dizzy with vertigo-like symptoms. I'm also finding it difficult to think logically. The symptoms set in about 12 hours after taking the pill. Today, I had numerous crying spells throughout the day, and I feel unable to control my rage. Yes, this drug certainly does curb your appetite, may help you with eating or other addictions, but the side effects that come with it aren't worth it. I won't be taking it ever again."

• Poc...
• January 13, 2021

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Took one Contrave tablet yesterday morning. As the day wore on, I could feel my heart beating really quickly. By 7 pm, my blood pressure was 151/94. Normally, it sits at around 110/80. By 9:30 pm, I was vomiting, sweating, diarrhea, and chills, and a terrible headache. I will never take this drug again, and I’m really seriously surprised that it’s available. It’s now 36 hours since I took the one tablet, and I still feel really nauseous and shaky. It’s just awful."

• Wor...
• July 7, 2021

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I took it thinking it won’t be so bad. I lasted 4 days before stopping it! It caused side effects of vomiting, dizziness, and headaches, which is pretty bad. I am really sick. Shaking as I am typing this. Worst drug to ever take! Please just lower your carbs and move more. Don’t take this drug, it’s the worst thing I have ever tried in my whole entire life."

• Mol...
• June 20, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I was prescribed Contrave by my doctor 3 weeks ago. I'm on week 3, and the side effects are just too much to deal with. My starting weight was 196 lb, and I've only lost 3 pounds. I work out 3x a week and walk daily. I changed my eating habits to stay under 1200 calories daily. Anyone who is looking to take this medication, hopefully, you can handle the nausea and vomiting, headaches, and sweats. I wouldn't recommend Contrave, it's not worth the money, in my opinion."

• Jil...
• Taken for 1 to 6 months
• October 10, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I started taking Contrave for menopausal weight gain. I started it 1 week before my fiancé left me for a millionairess. Not sure if it was depression or Contrave (likely a combination), but I lost almost 30 pounds in a month. Now it's been 6 months, and I'm down 34 pounds. I was vomiting the first week, but that went away quickly. The only other side effect is slight muscle twitching. I was barely overweight, but no diet or exercise would take the excess weight off. I'm thankful."

• Swe...
• Taken for less than 1 month
• April 16, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I have lost 10 pounds in 3.5 weeks. Hate the taste in my mouth, but I like the results. I think that the company needs to consider taking the fourth pill dose out of the regimen. If you have not gotten there, beware. It put me in the ER with severe trembling, numbness/tingling in hands and feet, creepy crawlies, severe dry heaves, violent vomiting, dehydration. My veins would collapse every time they tried to get an IV in me to counter the effects and hydrate me. I did fine on 1-3, but I was not having cravings on 3 and 4 is way too much, in my opinion. I hope this helps someone. I am going back to two a day for a while to let my body recover. Good luck!"

• Thi...
• Taken for 1 to 6 months
• April 2, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I've been taking CONTRAVE for about 2 months or so…and have had great success with it. It will make you nauseous at times, but it was pretty rare. For the most part, I just didn't care to eat (which was amazing…as I'm down 28 or so pounds!). I did a couple of things right; knowing that it could make me nauseous, I didn't stop eating pretty regularly for the first 5 or 6 days (and that helped my stomach handle it). But I've never been able to just forget to eat. Ever. In the 8 weeks, I threw up 4 times…which is the only thing I can see that could be dicey if I'm in a situation where I can't run to a restroom. But other than that, being able to lose that much weight (that I've never been able to get rid of in 20 years) was amazing. Miracle!"

• Anonymous
• Taken for less than 1 month
• March 3, 2022

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Took it for the first time today and experienced the worst nausea, vomiting, and headache I’ve had in a while. I don’t think I’ll take this medicine. I'm literally scared to take my second dose. $145 down the drain."

• ade...
• Taken for less than 1 month
• June 14, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I need to lose 20 pounds, and it is not coming off with diet and exercise. Doctor prescribed Contrave. I read many reviews before taking and was hopeful that I would not have side effects. I have taken Wellbutrin 150 XL with no problem. Before taking my first tablet, I had a breakfast of Greek yogurt and strawberries followed by 2 cups of black coffee and 8 oz of water. I took the tablet at 9 am. By 10 am, I had a strong pressure headache, felt dizzy, and was unable to concentrate. By 11 am, feeling nauseous. Tried sipping water and a few crackers, but by 11:30 am, I was vomiting violently and was unable to leave the bathroom for the next 3 hours. Fierce stomach cramps started around noon, followed by diarrhea. Headache worsened. Sleepless night. Yikes."

• Dus...
• Taken for 1 to 6 months
• January 10, 2021

For Weight Loss (Obesity/Overweight) "Been taking bupropion with naltrexone for 14 weeks. Before that, I was just taking 300 mg of bupropion prior to adding naltrexone. Insurance didn't cover Contrave. A $15 copay with naltrexone. Doc prescribed 50 mg a day. I am 5'6" and started at 207 lbs. Today I am 175 lb. I was horribly nauseous the first month or so and vomited often. I pushed through the first several weeks because the dosage was high to start with. I no longer have side effects. I have complete control over my eating now. No longer have cravings for junk food and have no desire to snack. I've been eating around 1050 calories a day, any more I feel like I've over eaten. My eating habits have completely changed. No longer eating processed food. The only thing I have a desire to eat is lean protein, fruits, and vegetables. This drug is setting me up for success because my habits have changed so dramatically. Thankful I pushed through several weeks of side effects. I'm now feeling great, losing weight, and excited about the progress to come."

• Anonymous
• Taken for less than 1 month
• February 18, 2016

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am a 36 yr. old mother of 4, and I started taking Contrave yesterday. Initially, I felt nothing. Until I started moving around, I became very jittery, then extremely clammy and hot. My mouth started to water, and I threw up all over the place. To say it made me nauseous is an understatement! I thought maybe it was because I ate a light breakfast before taking it. So I took it again this morning after a decent breakfast, and as I'm typing, I'm going through the exact same symptoms as yesterday. I'm going to discontinue using this as much as I was hoping I could continue to help with my weight loss, the symptoms are too harsh for me to continue."

• Jes...
• May 21, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I have to quit this medication. I'm just into week three, and I just can't handle the nausea. I'm miserable. Today, I was overcome with the vomiting, my final straw. I tried to keep going, thinking that, if I can just get through it. Between the nausea, the vomiting, the diarrhea, and the constant feeling of overwhelming tiredness... I can't. If the drug helps you lose weight by making you feel ill every day, then it's working! Nothing ever sounds good to eat, smells and visuals of certain foods now make me near vomit, and when I have food, I push it around on my plate or don't eat a quarter of what I used to. My doctor told me I wasn't getting enough calories now. Go figure. I spent a lot of money on this medication and had high hopes."

• Anonymous
• April 23, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "One week on Contrave. First few days were awful, with dizziness, vomiting, nausea. This seems to have passed. I thought it was helping with food addiction, however, I binge-ate last night and tonight. Today, I started taking two pills a day, so I will see how it goes. I'm hoping it doesn't affect my ability to sleep, but I'm worried about that as I'm usually crashed by 10 pm, and I'm wide awake at the moment. I may have lost a few pounds initially, I think, due to the upset stomach, but after the two-night binge, it's back on. Please, others share your experiences..."

• Ton...
• December 7, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "5 days, 5 lbs down. The nausea is making me sick. I hope it goes away soon. Not sure I can handle nausea every day for much longer. Do not have any alcohol on Contrave. I had 2 glasses of wine in 5 hrs, vomiting all night as if it was my first time having a glass of wine."

• Chr...
• Taken for less than 1 month
• July 5, 2021

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I have tried Contrave twice with disastrous results! The first time I reacted to it, I was told that it wasn't possibly related to the medication, but I stopped anyway. The symptoms I had were severe nausea, vomiting, fever, aches, and the worst part, a rash that peeled all my skin off a bit at a time from the top of my head to the bottom of my feet! It was intensely painful! I had stopped taking Contrave, and my condition improved over 18 months for my skin healing. Then, about 6 months ago, I decided to try it again as the doctors said that they were sure it was safe, so I took one pill from a new prescription, and within an hour, all the symptoms had come back! I did not take any more after that, but had to deal with the illness and skin peeling off again for 4 months, and it was terrible! It was concluded after seeing specialists that the rash, etc., was a result of Contrave, and it was very nearly deadly for me as this time it also caused an arrhythmia. I do not recommend using this product to anyone!"

• jim...
• August 15, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I started Contrave July 10, and I've lost 13 pounds already with little to no exercise. I'm at my second week of taking 2 pills in the morning and 2 pills at night. I have very bad side effects now, any time food touches my stomach, I get nauseated or vomit. I'm constantly tired, and I experience a little constipation. I'll be contacting the doctor to see if they will still be effective if I lower the dosage. I don't plan on stopping."

• Tam...
• Taken for 1 to 6 months
• April 14, 2019

For Weight Loss (Obesity/Overweight) "I've been taking the combination of bupropion/naltrexone for weight loss for a month. I started off at 220 lb, 5'8'', the heaviest I've been, and now I'm down to 207 lb! It does make me feel really nauseous at times, causing me to vomit. I do try to track what I eat using the MyFitness app."

• CBa...
• July 5, 2019

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "On day three, I experienced debilitating dizziness, extreme nausea, and violent vomiting. I had to call a family member to pick me up from work and drive me home. I switched the schedule and took 1 pill at night for two weeks. This helped decrease the side effects very little, and I still missed 3 days of work in two weeks due to the side effects. I continued taking the medication because I wanted to be successful. By week four, I had additional side effects of dry mouth, constipation, and I felt very foggy. By week six, I had lost 3 pounds and decided to stop taking Contrave due to the side effects. I didn’t even taper off, I just got so sick and tired of the side effects I just stopped taking the medication abruptly. It took about 2 weeks before feeling normal again. I was supposed to only have a three-month supply, but the medication was “conveniently” automatically reordered. Now I have a 2 1/2 month supply (that cost a lot of money) going to waste!! Not recommended."

• Yor...
• Taken for less than 1 month
• June 20, 2021

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Was prescribed by my doctor. On the 2nd day, I informed my doctor of severe vomiting and diarrhea. Told to discontinue use. Symptoms still continued and got worse. Couldn't keep anything down. Ended up in the ER. Would not take this ever again."