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Bupropion / naltrexone and Tiredness: What Users Say (Page 5)

Brand names: Contrave

Reviews for Bupropion / naltrexone

Commonly mentioned side effects
  • sar...
  • December 17, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I’m going to be completely honest, this is not a paid review. Contrave, I started it two days ago during the day around 11 a.m., and I felt sick. I was dizzy, had extreme nausea, diarrhea, and also I was tired, and I have a dry mouth. But I lost a pound in one day, my weight is 273 lbs. The next day I really wanted to stay on it, but I was scared because it had made me feel so sick, kind of like detoxification. I came on this site, read some reviews, and saw this one person say she took it at night. So she could sleep through the pain and side effects. Well, let me tell you something: no matter day or night, you are going to feel the side effects, no sleeping through them, that’s that. Yes, I have a low appetite and couldn’t finish my food."

5 / 10
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4 Report
  • Aks...
  • June 3, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Just purchased this drug last week, and what a waste of money. I feel very sick and bedridden. I only took two days' worth (2 pills), and I won't be taking it anymore. I cannot function on this drug. I've never been pregnant, but it feels like pregnancy symptoms are described: constantly nauseous, exhausted, and sensitive to smells. I do not recommend this drug."

1 / 10
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  • Not...
  • Taken for less than 1 month
  • March 21, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Been on this pill for 6 days and no loss of weight. First day felt weak, slept all day getting up to pee only. Woke up very hungry. 2nd and 3rd day abdominal pain, back pain, weak, and very hungry. 4th, 5th, and 6th day tired, feeling cramps but still eating a lot as very hungry. Wish I knew 4 pills needed to max results as I feel if 4 pills are needed, may not be effective. Discomfort not worth taking with no results. Too expensive, not covered by insurance. So far very disappointed and $90.00 less in pocket. Please buy a week at a time and see if it works for you. Talk to pharmacist."

1 / 10
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Frequently asked questions

  • Cru...
  • April 6, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I've been on it for 3 weeks as I need to lose 30 lbs. I've lost 2 lbs, but I'm super tired all the time. I still crave sugar, but it does suppress your appetite. Also, I am very cranky. I will finish out the bottle, then ask my doctor about another plan."

2 / 10
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  • Jen...
  • February 25, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I took the one pill 3 days ago and am still experiencing tiredness and no appetite. I was so sleepy and could not stay up while at work. I will not take the pill again. The fact that I am still having the effect 3 days later speaks volumes and is not a good thing."

3 / 10
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7 Report

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  • Gin...
  • Taken for less than 1 month
  • March 14, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "So day 1 is in the books, and boy was it a weird one. I took my pill in the AM. About an hour later, I felt dizzy, out of it, and very tired (which lasted all day), slight headache too. I do notice that I still get hungry, but it’s controllable now, and when I eat, I don’t overeat. I rightly ate about half as much as I normally would. I just hope this fatigue goes away."

6 / 10
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  • ass...
  • July 16, 2016

For Weight Loss (Obesity/Overweight) "Took Contrave for 1.5 months now. Down 12 lbs., which is nice. It's a slow pace. And I truly don't crave junk food a lot. I still might have a cookie. But I just have one. And I'm okay with one. When I eat a sandwich, I skip the mayo and chips with no problem. It's nice. This is how one is supposed to eat: rationally and with portion control. The downside is it gives me a headache and makes me tired. I also get annoyed quite easily and want to avoid social situations with bad food enablers and don't want alcohol."

6 / 10
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  • Mag...
  • Taken for less than 1 month
  • March 27, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Beginning week three, I stopped. Completely. So, two weeks in, this is why: (keep in mind, each week calls for a higher dose) - Awful, AWFUL insomnia began during the second week. - word dropping, forgetfulness - hot flashes, sweating, always feeling too warm - lethargic, no energy - Dry mouth. I mean Sahara desert dry! (Interestingly, did not induce a craving for water). Did it curb cravings? Not sure. I don't think so, but if it did a little, it still is not worth the high degree of downside."

2 / 10
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  • una...
  • Taken for less than 1 month
  • June 13, 2017

For Weight Loss (Obesity/Overweight) "Overall, I really like this drug and hope to be able to continue taking it and finally lose this weight. I lost 3 lbs in my first week, though none in my second week. SW: 199 GW: 150. This is my third try with Contrave. The other two tries have come to an end because I get really weepy. This time, I am titrating up at a slower pace and that seems to be helping. Side effects: upset stomach and lightheadedness for the first 3 days after titrating up. I have found that taking Bonine (anti-nausea tab) solves this problem. Exhaustion on days 2 and 3. Sleeping better and needing less sleep to feel energized. Constipation. My insurance does not cover this medicine. The out-of-pocket cost at Target for 120 pills is $90 with the manufacturer's discount."

7 / 10
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  • Myl...
  • September 24, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I took the first pill this morning with food. I feel very lightheaded, kind of dizzy, and kind of nauseous. I think I'll have to go home from work because I feel so tired as well. I don't think this drug is for me."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • June 16, 2017

For Weight Loss (Obesity/Overweight) "Started naltrexone/bupropion 5/1/17. 1 tablet naltrexone and 300 mg bupropion. SW: 249. Today: 235. F/5'1/42. I was desperate for some help, as I am also an alcoholic and have gained about 80 lbs in the last 2 years. This medication is a godsend to me. I can control my binge eating and also have much less desire for alcohol. Carb binge urges at nighttime completely gone, and I definitely reach for healthier choices now. I didn't give it the highest rating because I have one bad side effect: I am soooooo tired all the time. I have found that taking 1/2 pill AM with 150 mg bupropion and the other 1/2 with another 150 mg bupropion in the afternoon helps. Will stay on this as long as possible."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 25, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "The reviews made me skeptical. Most reviews cited nausea as a major side effect. The doctor assured me that only 1/4 of users experience this. Ok. First week nothing, almost even felt really happy! Week two increased dosage and felt extremely foggy, tired, nausea, and vision problems. No thank you! No amount of weight loss is worth feeling that awful. After again reading the literature, it looks like this drug would only help lose 5% of body weight over a year's time. That’s only ten pounds for a two hundred-pound person. They need to go re-tweak this drug. I feel horrible and I hope when I don’t take it tomorrow I won’t end up feeling worse yet."

4 / 10
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  • Sas...
  • February 19, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I couldn't give this a high rating because I just started this yesterday, 2/18/17. Took it and overall seemed okay. I did feel a little tired. I slept very well, but did have one crazy dream/nightmare, and from reading the other reviews, I'm thinking it's from the medication. I do feel really tired today. I hope I don't feel like this all the time, but it's only the 2nd day. I will continue for a week or two and see if I see a difference."

3 / 10
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10 Report
  • Dee...
  • Taken for less than 1 month
  • August 7, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I just started the 2 pills in the morning and one pill at night today. I have had no effects whatsoever other than feeling tired. I have lost no weight and am hungry all the time. I will continue it but not for much longer, very disappointed."

1 / 10
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  • Jam...
  • Taken for less than 1 month
  • January 12, 2016

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I have been taking this medication for a little over a week now. I have not weighed myself to see if there has been any weight loss. I am a 38-year-old female, 230 lbs, 5'2'', looking to lose around 50 lbs. I have been very nauseated and tired since taking this medicine. I usually have no taste for anything and typically eat just because I am used to eating at a certain time. However, I have a hard time eating a full meal because everything just doesn't taste good to me anymore. I started taking my 2 pills a day yesterday and took the evening dose around 6 PM, not sure if taking it that late caused me to have trouble going to sleep or if the feeling of nausea was the reason. Hoping my body will adjust soon. Will keep you all updated on progress."

5 / 10
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  • Ras...
  • Taken for less than 1 month
  • July 6, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Started the 3rd week of Contrave yesterday, was initially down 2 lbs and then 3 down but back to only 2 lbs. Got a cold last week, so have not been eating as much, but still nothing major. Started back to the gym also. First week, tired, slightly dizzy, but that was it. Second week, forgot one night and took the pill after dinner (about 30 minutes later), and my stomach was upset all night, but no vomiting or diarrhea, which would have helped! Third week, took two pills in the AM and several hours later, extremely dizzy and funny headaches. Same thing today, and still nothing major. I am not really seeing any major change in appetite at all. I don't really feel like this pill is working, which is sad because my insurance did not cover it, and I had to pay $99.00 for these things."

4 / 10
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  • I...
  • Taken for less than 1 month
  • February 21, 2016

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I took my first pill today. Spent the next 9 hours literally asleep or standing over the sink. Within one hour of taking it, the nausea started, at 2 hours, the dizziness and tiredness. I felt worse than when I had the full-blown flu. STAY AWAY!! There are better, less toxic options!"

1 / 10
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  • Sun...
  • Taken for less than 1 month
  • October 16, 2019

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Been on it for a week now and lost like a lb each day, works great, I'm a little tired from time to time."

10 / 10
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53 Report
  • swm...
  • January 28, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I'm not sure I can do this medication. I feel dizzy and extremely tired of it. I'm on my third day, hoping the side effects go away. But my appetite is definitely curbed."

3 / 10
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58 Report
  • Gra...
  • Taken for less than 1 month
  • March 8, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "On day 5, not hungry, but so tired I can barely function. Hopefully, it will go away. Hate feeling tired and foggy."

5 / 10
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23 Report
  • Gea...
  • April 8, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Today I started the 2 in the morning, 1 in the evening dosage. I am so lethargic and sleepy, I even took a nap on my lunch break. I haven't lost any weight either."

1 / 10
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23 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.