Skip to main content

Bupropion / naltrexone and Tiredness: What Users Say (Page 3)

Brand names: Contrave

Reviews for Bupropion / naltrexone

Commonly mentioned side effects
  • wor...
  • Taken for less than 1 month
  • April 20, 2018

For Weight Loss (Obesity/Overweight) "I am 5'4" and 212 lbs. I have always been curvy (usually weighing 155 lbs), but after baby #4, my body really changed, and cravings got out of control. Day 4 of taking 1 pill a day. I decided to cut the pill in half and take half in the AM and half in the afternoon, just to help my body adjust to the RX. The first 2 days, I felt very dizzy. I have felt the nausea for sure. I feel extremely tired in the afternoon, usually. On the plus side, I barely eat anything, and I can definitely say NO to food, even the sweet stuff. 4 days and 1.5 lbs down already. I will update every couple of weeks. Good luck to everyone. The struggle is real. Week #1 complete now, and total weight loss is 5.2 lbs. Still get nausea, headaches are minimal, and I still get fatigued. But happy to deal as long as I am losing weight."

6 / 10
Was this helpful?YesNo
15 Report
  • sco...
  • February 4, 2016

For Weight Loss (Obesity/Overweight) "I have been on this for about a month. I was 345 lbs when I started and got as low as 317 lbs. I have had headaches, no nausea, but I do feel tired all the time. But I also have seasonal affective disorder, which may play into it. I cheated a little by upping my dose every 5 days instead of every 7, but now I've hit a plateau. I'm hoping that I start losing again 'cause so far this is the first time I've been able to lose weight. This is my last hope. I haven't done any exercising because I'm disabled, and it's tough for me. I'm hoping I can start once I lose more weight. It caused constipation and diarrhea at times. I have gotten abdominal cramps if I try to eat too big of a portion or eat too frequently. I have noticed that I eat a lot less."

8 / 10
Was this helpful?YesNo
16 Report
  • Hop...
  • Taken for less than 1 month
  • November 7, 2015

For Weight Loss (Obesity/Overweight) "I have been on this medication for a little less than a month, and as of today I have lost 10 lbs!! So the only side effects I have had were being tired and very foggy-minded, but since the third week both of these side effects have gone away. I was told by the doctor that side effects are very common for the first 4 weeks, then they should go away because your body has adjusted to the med. I still have about 60 lbs to lose to be at a healthy weight for my height. I am a 28-year-old female whose starting weight was 194 and height is 5 ft 6 inches. I gained most of my weight from my pregnancies, all three of my girls being back-to-back."

10 / 10
Was this helpful?YesNo
17 Report

Frequently asked questions

  • Ars...
  • Taken for less than 1 month
  • October 4, 2017

For Weight Loss (Obesity/Overweight) "I was so nervous to try Contrave for the first time after reading the reviews. The moment I took the first pill, I was instantly sick. Well, the problem was that I took it on an empty stomach. I am now on week 3 and have had no other side effects. Today, I am super tired and can’t keep my eyes open, I’m not sure if it’s the Contrave or not. Also, I’m down 7 pounds."

10 / 10
Was this helpful?YesNo
11 Report
  • mic...
  • July 30, 2017

For Weight Loss (Obesity/Overweight) "I have been taking this medication for about 4 days now, still feel hungry and have somewhat of cravings, but I usually never have extreme cravings to begin with. That being said, I did read someone's review declaring not to quit yet, because it took at least the 2nd week before she actually felt like something/Contrave was working. So I am hopeful that this is true. The drug does make me SUPER, super tired, which sucks, as I suffer from chronic fatigue due to a tick-borne illness. I'll stick with it and I will post an update then....."

2 / 10
Was this helpful?YesNo
11 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Jes...
  • May 21, 2015

For Weight Loss (Obesity/Overweight) "I have to quit this medication. I'm just into week three, and I just can't handle the nausea. I'm miserable. Today, I was overcome with the vomiting, my final straw. I tried to keep going, thinking that, if I can just get through it. Between the nausea, the vomiting, the diarrhea, and the constant feeling of overwhelming tiredness... I can't. If the drug helps you lose weight by making you feel ill every day, then it's working! Nothing ever sounds good to eat, smells and visuals of certain foods now make me near vomit, and when I have food, I push it around on my plate or don't eat a quarter of what I used to. My doctor told me I wasn't getting enough calories now. Go figure. I spent a lot of money on this medication and had high hopes."

3 / 10
Was this helpful?YesNo
14 Report
  • jim...
  • August 15, 2015

For Weight Loss (Obesity/Overweight) "I started Contrave July 10, and I've lost 13 pounds already with little to no exercise. I'm at my second week of taking 2 pills in the morning and 2 pills at night. I have very bad side effects now, any time food touches my stomach, I get nauseated or vomit. I'm constantly tired, and I experience a little constipation. I'll be contacting the doctor to see if they will still be effective if I lower the dosage. I don't plan on stopping."

5 / 10
Was this helpful?YesNo
13 Report
  • Jad...
  • Taken for less than 1 month
  • August 7, 2017

For Weight Loss (Obesity/Overweight) "Started on Contrave 8/5/17. First day I was lightheaded, nauseous, tired. Didn't feel like doing anything. I debated if I should take the pill at night instead, but went ahead and took it in the morning to see how I would feel on the 2nd day. Well, I didn't feel as bad on the 2nd day compared to the 1st day. 2nd day I wasn't lightheaded but just felt nauseated and tired. I would get hungry but couldn't eat much because I felt full once I ate 2 to 3 bites. I am at 192 lbs, will update after 1 week."

7 / 10
Was this helpful?YesNo
11 Report
  • Gwe...
  • June 6, 2017

For Weight Loss (Obesity/Overweight) "Severe nausea with the first pill, and it lasted 2 days. Anti-nausea pills did not help, and I was nauseated again and could not function for two more days. I was miserable. I am on no other meds. Also lethargic."

2 / 10
Was this helpful?YesNo
13 Report
  • pay...
  • Taken for less than 1 month
  • March 2, 2017

For Weight Loss (Obesity/Overweight) "Started taking on February 27th. I was already counting calories and exercising 5-6 days a week, but nothing moves the scale. The first few days, I'm so tired after taking. This seems to be the only side effect. I have a slight headache, but I think that's due to not eating, as I'm just not hungry. Goal is 80 lbs, I'm 250, 5 ft 9."

4 / 10
Was this helpful?YesNo
12 Report
  • Anonymous
  • January 11, 2016

For Weight Loss (Obesity/Overweight) "I started taking Contrave 1/7/16. Weighing 204 lbs and am 5'1. I just had a baby 12-13-14 and been eating so much after. Since I started, been feeling a bit tired for some reason, no headaches, I can't concentrate on anything, almost as if I have no thoughts and at times feel sad all of a sudden, had mild cramps and been having more soft stools often, it's nothing too bad. I weighed myself today on my 5th day and I weigh 199.2, so I have lost 5 lbs. I have been eating less, twice a day and 2 snacks. Before, I'd snack a lot and eat 3 to 4 full meals. I'm surprised to lose a pound a day, not sure how because I don't exercise at all. I actually don't feel motivated to do anything. It's weird. It's just been about 5 days, let's see how things go."

7 / 10
Was this helpful?YesNo
12 Report
  • Pha...
  • Taken for less than 1 month
  • June 30, 2016

For Weight Loss (Obesity/Overweight) "I am on day 3 of the plan. I kinda feel a little different. My cravings are not as intense for food or nicotine. No real side effects other than feeling tired in the afternoon. After reading some of the reviews, I was a little worried, but I'm going to stick with it. I will check in next week."

6 / 10
Was this helpful?YesNo
11 Report
  • da ...
  • October 26, 2015

For Weight Loss (Obesity/Overweight) "I've been on Contrave for almost 4 months, lost 23 lbs. Doctor wants me to lose at least 40 - my goal 45. Up until 2 weeks ago, only side effects: dry mouth, constipation, and craving for chocolate, which I never had before. Those effects went away. Now I'm experiencing nausea, dizziness, and tiredness. It could be the possibility of not drinking as much water as I did during the warmer months. I'm going to see if it makes any difference. I thought maybe decreasing the dosage may help. Then I saw someone write about Bonine and how that helped."

7 / 10
Was this helpful?YesNo
11 Report
  • Lom...
  • September 6, 2015

For Weight Loss (Obesity/Overweight) "I need to lose about 20 pounds. My doctor was on Contrave and lost 30 pounds. I started taking Contrave and within less than 24 hours, was experiencing headaches, jitters, sleepiness, dry mouth, and was very lethargic. I usually don't experience side effects with new medications, so I continued taking this for 1 week. Didn't get any better and stopped taking it altogether."

2 / 10
Was this helpful?YesNo
12 Report
  • Lyn...
  • Taken for less than 1 month
  • April 12, 2017

For Weight Loss (Obesity/Overweight) "Started April 5th. Took around 8 a.m., and by 10:30, I had to stop work because I was extremely dizzy, nauseous, and wow, so tired. Didn't take it again for 2 days, then tried again, this time I now take it at 3 a.m., go back to sleep so I sleep through the side effects. 3 days of doing this, and so far, so good. I do need an extra coffee through the day, though, to keep awake. Have lost 2 lbs in a week. Kind of scared going to 2 pills, may wait another week."

5 / 10
Was this helpful?YesNo
8 Report
  • Anonymous
  • June 20, 2016

For Weight Loss (Obesity/Overweight) "I started taking Contrave 6/1/16. I am a 25 yr old female, starting weight 178. Since starting, I have lost 10 lbs!! For the first week, I did stay very tired. But other than that, no side effects. I am still able to eat the foods I want, but with this pill, I know when to stop. I literally still eat whatever I make for supper, but I'm just more aware of how much I'm eating. I exercise a few times a week, but not much. I will continue until I reach 155! I'm hoping that once I stop taking the Contrave, I will keep the habit of not overeating."

8 / 10
Was this helpful?YesNo
10 Report
  • Ama...
  • Taken for less than 1 month
  • July 24, 2017

For Weight Loss (Obesity/Overweight) "I paid $99 for 120 pills. Insurance did not cover, but the doctor gave me a prescription card from the manufacturer. You just go online and fill out some information. Day 1, I took the pill at 8 AM. I felt fine until 2 hours later (I think since it's time-released, that is when the side effects hit me). I got so tired at work and felt so nauseous. I figured I'd leave my office, and while I was driving, I threw up on myself. Day 2, I ate a good meal when I took the pill and brought snacks. 2 hours later, I hit that wall and was so tired and nauseous. I didn't throw up, so maybe snacking helped, but I was miserable. I have never taken anything that made me feel this bad. The next day was a Saturday, and I had plans, so I decided not to take it."

2 / 10
Was this helpful?YesNo
8 Report
  • Tfo...
  • July 19, 2016

For Weight Loss (Obesity/Overweight) "I am on my 4th day with the medication. The first 2 days were tough. Feeling very tired and nauseous. The nausea has stopped, I found that if I eat before taking the pill, it helps. The tired feeling is still present, but it's getting more tolerable. I also have a very dry mouth and my attention span is a little out of whack. I am finding that on one pill I am not as hungry during the day, but by dinner I'm starving. I can see how my eating habits are changing a little bit every day. I plan on sticking with the medication unless side effects worsen. I haven't tried working out yet, but hoping when I shed a few pounds I will find the energy to. They are more tolerable than anything else I've tried."

8 / 10
Was this helpful?YesNo
8 Report
  • Com...
  • November 15, 2017

For Weight Loss (Obesity/Overweight) "So I’ve been on the medication for 4 days and have already lost 7 lbs. I’m 29 and started out at 227 lb and am now down to 200 lb. To be fair, I have an amazing doctor. She prescribed this to me only if I changed my diet. I cut out most carbs and sugar, plus an hour of exercise. This isn’t a magic pill that’s going to make you lose a lot of weight by just taking it and not changing your lifestyle. The only side effect I had was nausea and tiredness. But again, I have completely changed my diet, so that could contribute to that as well."

10 / 10
Was this helpful?YesNo
7 Report
  • Dis...
  • Taken for less than 1 month
  • February 22, 2017

For Weight Loss (Obesity/Overweight) "I have been on this medicine for two weeks now. I have read a bunch of those comments, and they all helped me. Thanks. I put them all together, and here is mine. Honestly, IT'S NOT WORKING! I take it with food, I have nausea, I get tired (the first day, I was so sleepy), dizzy, afternoon hunger, still crave carbs in the middle of the day, headaches, stomach pain, and now that I take one at night too, I understand, after reading some comments, why I have been having weird dreams. I have an appointment with my doctor coming in March because she told me CONTRAVE can increase my blood pressure, and she wants to monitor very closely. I also feel bad about the price. Not worth!"

1 / 10
Was this helpful?YesNo
9 Report
  • Gym...
  • April 9, 2017

For Weight Loss (Obesity/Overweight) "I started the meds this morning. Went to the gym, had a pretty good workout. Felt a little lightheaded this morning while at the gym. Got home, started craving water. While traveling this afternoon, noticed I was getting very edgy and had a lot more energy and was hungry. BUT I ate at 8 am, then the gym, and didn't eat when I got home, so... I was still wanting water a lot. Five hours later, I was very tired, edgy, and my husband said I was slurring my words. We ate dinner around 6, and I was fine. Not traveling again, and it's 9:20, and I am so sleepy. Better mood per my husband."

2 / 10
Was this helpful?YesNo
11 Report
  • Can...
  • Taken for less than 1 month
  • March 17, 2018

For Weight Loss (Obesity/Overweight) "I’m starting week 2 and, like most, I’ve been so hesitant in taking Contrave. My cravings have gotten a lot better. I’ve been extremely tired every day, which lasts all morning. Dizziness comes and goes, but no nausea or even headaches. I’ve felt like my head was in a cloud. I did have constipation, but then, out of nowhere, I’ve had diarrhea. I got on the scale and lost 3 lbs, but not sure if that was because of the diarrhea - I hope not. I’m going to continue and follow the dosage, but I’ll be honest, I’m scared as anything, but I’m also desperate to lose weight. Before Contrave, I was constantly eating all day long, and the weight just kept adding on. I’ve tried so many diets, and nothing ever really worked, so I’m hoping Contrave is the one."

6 / 10
Was this helpful?YesNo
6 Report
  • Bel...
  • Taken for less than 1 month
  • February 25, 2018

For Weight Loss (Obesity/Overweight) "I was given Contrave last June, but it did not work. A few weeks later, I was diagnosed with ovarian cancer, so I'm wondering if that is why it was not working. After surgery and five months of chemotherapy, I am pleased to say I am now in remission. So now I'm cancer-free, I am thinking of trying Contrave again. I put on more weight during my illness, so I think losing some weight may help me feel better. I have no energy and tire easily. If anyone knows if cancer stops this drug from working, I'd like to know. Thanks."

8 / 10
Was this helpful?YesNo
7 Report
  • Bel...
  • Taken for less than 1 month
  • February 25, 2018

For Weight Loss (Obesity/Overweight) "I was given Contrave last June, but it did not work. A few weeks later, I was diagnosed with ovarian cancer, so I'm wondering if that is why it was not working. After surgery and five months of chemotherapy, I am pleased to say I am now in remission. So now I'm cancer-free, I am thinking of trying Contrave again. I put on more weight during my illness, so I think losing some weight may help me feel better. I have no energy and tire easily. If anyone knows if cancer stops this drug from working, I'd like to know. Thanks."

8 / 10
Was this helpful?YesNo
7 Report
  • Jos...
  • Taken for less than 1 month
  • January 3, 2021

For Weight Loss (Obesity/Overweight) "The nausea, the headache, and very lethargic. I worked since I have significantly less craving, but I can't tolerate being in this horrible condition. This is not worth it. Every day when the medication wears off in the late afternoon, I will have a bad episode of nausea for around 1-2 hours, exactly 6 hours from my second dose daily, and it didn't get better after 2 weeks, so I decided to stop."

2 / 10
Was this helpful?YesNo
5 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.