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Bupropion / naltrexone and Nausea: What Users Say (Page 4)

Brand names: Contrave

Reviews for Bupropion / naltrexone

Commonly mentioned side effects
  • JoM...
  • June 3, 2015

For Weight Loss (Obesity/Overweight) "I have been on Contrave since Jan. 15. The side effects can be horrible the first 2 weeks as your body adjusts to the meds. It does get better and it is so worth pushing through them. Bonine is awesome for the nausea, extra-strength Excedrin Migraine works wonders for the headaches, and Phillips products are the best cramp-free choice for constipation. I am down 35 pounds and 5 pounds away from my goal weight. Contrave has stopped me from binge eating and it gives me the strength to turn down junk food without feeling deprived. I know I am responsible for me and the choices I make, Contrave is just a tool to help me. Contrave doesn't curb my appetite but it gives me resolve to make better choices. I can't do it without Contrave!"

10 / 10
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  • luu...
  • Taken for less than 1 month
  • June 3, 2023

For Weight Loss (Obesity/Overweight) "The worst side effects I ever experienced. Since the first pill, I had dizziness, nausea, I vomited several times, I can't eat anything because I feel so sick. I can't believe a doctor prescribed this to me. I want this to work, but I have literally spent 5 days in bed because I can't do anything. This thing is poison. Today is my last day taking this."

1 / 10
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  • Mel...
  • June 22, 2015

For Weight Loss (Obesity/Overweight) "I am so thrilled with Contrave. I am 40, female, 5'4", weighed 268 when I started the meds about 12 weeks ago. I am now 240! 28 lbs in 3 months! This is the easiest weight loss that I have ever had. Trust me, I have lost and gained probably 350 lbs over the last 20 years. And I always suffered. This Rx has changed everything. I don't obsess over food anymore. I don't binge. I know when to say when. It's like the switch got turned back on between my brain and my stomach. I have very few or lasting side effects. I have had some slight nausea and tummy discomfort, but I always have had that, so not a big deal. The only lasting effect that I have noticed is hand trembling. It's annoying, but so worth it."

10 / 10
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Frequently asked questions

  • Deb...
  • December 21, 2017

For Weight Loss (Obesity/Overweight) "I started taking Contrave in the middle of October 2017. I just went back to the doctor in the middle of December 2017. I have lost 25 lb in about 9 weeks. I'm absolutely thrilled with this medication, it has taken all my cravings away, and I'm not hungry. I actually have to force myself to eat. The side effects for me are I get nauseous sometimes, and there is a heavy feeling after I eat. I usually can only eat about 5 or 6 bites of something, and I'm completely full. My cravings for certain foods are completely gone. I am now going to incorporate going to the gym and riding a bike four to five times a week, and I may even get better results. I'm very excited to continue on this medicine and continue on my weight-loss journey."

10 / 10
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  • Tri...
  • August 9, 2016

For Weight Loss (Obesity/Overweight) "So I went back and forth about starting Contrave, weighing 275, and nothing was really working for any length of time long term. I decided to try. I started in May, and it's now August, I'm currently 245. It's been quite some time since I've been here. All that said, I will say the first week sucked... I was nauseated, had stomach cramps, felt like crap. Every day I debated with myself if I was going to continue taking it, but I wanted to try, even though I felt bad. I'd say for the first month I wasn't hungry, and I couldn't finish all of whatever I put on my plate. I didn't have a desire for sweets or fried anything. Now, those cravings have slowly come back, but I'm still eating smaller portions. Keep an eye on your blood pressure and don't drink alcohol."

8 / 10
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  • Bec...
  • August 7, 2019

For Weight Loss (Obesity/Overweight) "Do your research, please. Side effects are not precautionary, they are severe. If you read other reviews, it’s clear that 70% have debilitating side effects. You won’t find a lot of journeys on YouTube or blogs because people discontinue use - that’s the first clue. Despite this, I gave it a go. Day 1 was all I could tolerate. I felt drunk, dizzy, and nauseated. Walking down the hall, I fell into the wall suddenly from a huge bout of dizziness. That was it for me. I don’t doubt you will lose weight, but I do doubt it’s good for you. People have reported constant nausea, hair loss, rapid heartbeats, ear ringing, dizziness, BP increases, headaches, side effects after months of use, and sudden bouts of anger/depression. Heart studies have not been fully done as well, which should be noted. It depends on how desperate you are to lose weight. All I have to say is research and calculate your own statistics. This medication is clearly harsh and messes with your body/mind. Good luck!"

1 / 10
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  • Bec...
  • August 7, 2019

For Weight Loss (Obesity/Overweight) "Do your research, please. Side effects are not precautionary, they are severe. If you read other reviews, it’s clear that 70% have debilitating side effects. You won’t find a lot of journeys on YouTube or blogs because people discontinue use - that’s the first clue. Despite this, I gave it a go. Day 1 was all I could tolerate. I felt drunk, dizzy, and nauseated. Walking down the hall, I fell into the wall suddenly from a huge bout of dizziness. That was it for me. I don’t doubt you will lose weight, but I do doubt it’s good for you. People have reported constant nausea, hair loss, rapid heartbeats, ear ringing, dizziness, BP increases, headaches, side effects after months of use, and sudden bouts of anger/depression. Heart studies have not been fully done as well, which should be noted. It depends on how desperate you are to lose weight. All I have to say is research and calculate your own statistics. This medication is clearly harsh and messes with your body/mind. Good luck!"

1 / 10
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  • Bas...
  • March 28, 2016

For Weight Loss (Obesity/Overweight) "I'm in the middle of my second week of Contrave. The first day, I had an odd feeling and a bit of nausea, but water and half of a sandwich was a quick fix. I decided to move my dosage up a couple of days early to avoid any issues with weekday work hours, so I increased my dosage on a Sunday. I'm glad I did. The nausea came back on the first day of my dosage increase, so I treated it with water every time I had a sour feeling in my stomach. The water helped, and when it didn't, I would have half of a sandwich or some soup. I started my two in the morning and one at night today. I found myself picking at my Easter dinner and refusing dessert altogether. I've lost eight pounds in 16 days without trying."

9 / 10
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  • She...
  • Taken for less than 1 month
  • February 8, 2016

For Weight Loss (Obesity/Overweight) "I started Contrave at my doctor's request on Jan 14th at 224 pounds. This morning I was 215. I've had virtually no side effects. My doctor said to lose 8 pounds per month, and I've lost 9 pounds in just short of a month. I've noticed that drinking lots of water and spacing out meals and snacks has kept the nausea at bay. I take my 1st dose at 6:30 am with my breakfast. I eat a piece of fruit at 10:30, lunch around 1:30, a Fiber One snack at 3ish, then dinner around 6 with my second dose. High-protein snacks have really helped a lot."

8 / 10
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  • Sas...
  • December 18, 2018

For Weight Loss (Obesity/Overweight) "Today's the beginning of my 4th week/start of full dosage. In 3 weeks, I've lost 7 lbs and haven't exercised... yet. I'm 5'8" & started at 221 lbs. I am a mostly healthy eater, but struggle with portion & snacking. The first 2 days, I felt mild nausea. Constipation began today. I had to be conscious of eating smaller than normal portions. My favorite part is no longer feeling 'hangry' at times. I can feel when I get hungry, but I don't get ravenous if I put it off. I no longer snack at night. I can get the winter blues and think the anti-depressant in this medication has helped that too! Coffee & wine taste was not affected. I think that the official results are supposed to be a 9 lb loss. I really don't understand this by reading through the reviews stating huge losses and my own loss. With the discount card, it's $115 at the pharmacy. If they fill and deliver, it's $100. I understand that about 25% of people will not tolerate side effects, but we're all different."

10 / 10
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  • Kai...
  • Taken for 1 to 6 months
  • February 21, 2017

For Weight Loss (Obesity/Overweight) "I have to say that Contrave works. I have been on this medication since the beginning of December. I didn't have any of the side effects in the beginning. I have lost approximately 20 lbs at this point. I have no more cravings for coffee or sweets. I no longer like the taste of wine, which I recently discovered. I try to take the dosages 12 hours apart and have learned not to take it on an empty stomach. Within the past 2 weeks, I have had bouts of nausea and vomiting. I am fine after that, but absolutely think it has something to do with my stomach not tolerating acidic foods, unusual for me. I have learned to have a different relationship with food. I now eat to live instead of living to eat."

10 / 10
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  • I...
  • Taken for less than 1 month
  • January 11, 2017

For Weight Loss (Obesity/Overweight) "I knew to expect side effects and mentally prepared myself to push through as best I could. But as the constant heaviness in my head, the whole-body dizziness, loss of coordination, blurred vision, constant nausea, and fear of suddenly projectile vomiting at my work desk became harder to cope with, I gave myself permission to quit. As much as I want this medication to work for me, I cannot imagine putting myself through 2 more weeks of titrating my dose up to 4 pills a day, only to then find that my body never adjusted to the dosing and I felt sick nearly every moment of the day for a month only to have to titrate back down over the course of another month. I got up to 2 pills and just couldn't take any more of the unwavering side effects."

2 / 10
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  • Anonymous
  • August 4, 2020

For Weight Loss (Obesity/Overweight) "After 5 days of taking Contrave, I had severe constipation. So bad that after taking a laxative, I was puking and almost passing out. Finally, after a couple of hours, I was able to go. But after being off of Contrave for 3 days, still having issues of constipation and nausea. This pill is not worth this major side effect."

1 / 10
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  • Gra...
  • June 1, 2019

For Weight Loss (Obesity/Overweight) "Summary: this medication does work, but the side effects are absolutely brutal. There is nothing I want to do less than eat. Five hours after taking the medicine for the first time, I'm feeling extremely ill. I've gone from a healthy and productive individual to experiencing the worst lightheadedness of my life, along with nausea, headaches, dizziness, and stomach aches. This is the first and last day I'll be taking this medication. I can barely stand for more than a minute before everything gets fuzzy and I feel lightheaded. I am confident that if I were at work, where I have to stand, I would have passed out within the first 10 minutes of my shift. Right now, I feel fully incapacitated and confined to bed until I can get this medication out of my system. I'll update here how long it takes to get the medication out of my system for anyone in the same boat. I'm 5'5 and 180 lbs for reference."

6 / 10
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  • Hop...
  • Taken for less than 1 month
  • July 18, 2016

For Weight Loss (Obesity/Overweight) "I was hesitant to start Contrave after reading the reviews' side effects. Took my first pill a week ago. Started out at 277, one week later, am at 271. I wasn't expecting certain cravings to be eliminated so quickly, but am super pleased they were. After the second day on Contrave, my 30+ year addiction to coffee and cream just vanished. What? I literally have not gone one day in my adult life without coffee and cream. I am now having tea in the morning. Also, very quickly, other things I really like have gone off the list of things that now gross me out completely: sweets with high fat content and creamy foods: chocolate mousse, ice cream, coconut milk, etc. Will continue to update. Am having weird, vivid dreams, dry mouth, and slight nausea."

10 / 10
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  • In ...
  • Taken for 1 to 6 months
  • July 9, 2021

For Weight Loss (Obesity/Overweight) "I have been on Contrave for just over 8 weeks and have lost 26 lbs. I am using it with the WW purple plan (using the app), and it is doing the trick. I am a 61-year-old female with a long history of obesity that has gotten worse over the years. I have been off and on WW before, and it works, but I don't stick with it. I think the Contrave will help me stay on the plan. At the very beginning, I had some lightheadedness and queasiness, and that came back for a short time each time I ramped up the dose, but I stuck with it and now don't have side effects. The only time I feel bad is when I overeat or eat very rich food, and that is the meds' way of telling me to cut it out. I do not obsess over food anymore and can ignore the doughnuts and other junk food in the breakroom at work. I am paying about $100/mo out of pocket, and it is well worth it! I have a long way to go, but so far, so good."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • March 14, 2022

For Weight Loss (Obesity/Overweight) "This medicine is very good at helping you lose weight. So far, in about 3 months, I lost 42 pounds not exercising regularly or dieting. It cuts your appetite. It made me nauseous at first until I got used to it after a month or so, and when I had to stop, I kept the weight off and even lost a little extra. Love it!"

10 / 10
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  • nom...
  • April 18, 2015

For Weight Loss (Obesity/Overweight) "Love this medicine. Have been on it a little over 2 mos and have lost 16 lbs. I have not had any bad side effects, and I take 2 in the morning and 1 in the afternoon. I can still eat on Contrave, I just fill up faster, so I'm eating less. It has helped me to eat smaller portions. When I first started taking 2 in the morning, it made my stomach a little queasy, but that subsides quickly. I plan to continue taking it! I also like the messages I receive every morning when I weigh myself, they encourage and motivate me. The weight loss and better eating habits have rubbed off on my family, and they are eating better and less."

9 / 10
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  • Blu...
  • April 14, 2016

For Weight Loss (Obesity/Overweight) "Day 1 was full of side effects. Day 2 they subsided. I became very lethargic. A slight headache. Dizziness and overall, wasn't feeling well. I take something for the nausea and go to sleep. I take my pill with 16 oz of water DURING my meal to help alleviate stomach upset. I have so much more energy. I weigh in soon. Mentally, I have clarity and feel positive. Because of the depression, it was hard for me to get up or complete tasks. After 5 days, I am working out every day. My body doesn't ache. I don't 'feel depressed.' The side effects are worth my sanity and beat suffering from obesity. I see this as the tool I've needed to help me get my life back. Depression/obesity is a disease, and this is helping with my treatment."

8 / 10
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  • Cur...
  • Taken for less than 1 month
  • August 5, 2017

For Weight Loss (Obesity/Overweight) "I just finished my first week of Contrave with metformin, and I have lost 11 lbs already. With PCOS, this is the first time I've seen weight loss like this. I do have some upset tummy and nausea, and I have to force myself to eat because I am not hungry at all anymore. I am really hopeful. Down from 276 to 165. I haven't added exercise yet and am really hopeful. Will update."

10 / 10
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  • Thi...
  • April 22, 2016

For Weight Loss (Obesity/Overweight) "I have been taking Contrave since Feb 2016. Male - 63. I have lost 25 lbs. so far with little to no exercise. 327 down to 302. The only side effect I noticed was a little nausea in the first week, but it went away after that. I have not suffered any other effects as in testimonies from others. This product does block the hunger feeling and the full satisfied feeling. I watch what I eat, reduce portions, and have cut out most carb consumption. I will be taking walks soon now that winter is over. I recommend Contrave, however, as it is stated in the product information, this may not be for everyone. The side effects described concerned me in the beginning, but I have confidence in the product now."

9 / 10
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  • Anonymous
  • February 9, 2017

For Weight Loss (Obesity/Overweight) "I started Contrave in October of 2016 with a starting weight of 159. In the beginning, I didn't notice any changes, I actually felt like I was eating more for the first few weeks. I had a few side effects - headaches, nausea, constipation, hot flashes, but those have since gone away. It's now February 2017, and I'm happy to say that I am down 25 pounds! Very happy with the results."

10 / 10
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  • sse...
  • March 2, 2016

For Weight Loss (Obesity/Overweight) "I have been taking Contrave since October 2015. I have been going to the gym for 2 years, 4 to 5 days a week. My results came to a halt. After starting Contrave, I have lost 25 lbs and continue to see results. I do have some nausea when I don't eat when I should. This just reminds me to eat a snack, which is usually cheese and almonds. Some of us just need a little help. I am 5'4", start weight 179, as of today, 154. Thank you, Contrave! You have truly changed my life."

9 / 10
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  • Glo...
  • Taken for 1 to 6 months
  • August 30, 2017

For Weight Loss (Obesity/Overweight) "Started at 243 lb, I am down to 226 lb. Started about 5 weeks ago. So I was finally on 4 pills a day until the 5th week, but I had two days of extreme stomach ache. I came down to 3 pills, 2 in the morning and 1 at night. The weight has steadily declined about 2 to 3 pounds a week. Truly glad I started the medication. I have had some of the side effects. The nausea, I use peppermint or gum to overcome. Constipation and dry mouth, I drink more water. I do get a jittery feeling, but it does go away. No issues with sleep. Take B12 pills for energy. So far, so good. But I am glad it is working. It was $227 under insurance, but the coupon dropped it down to $99."

7 / 10
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  • LLa...
  • Taken for less than 1 month
  • October 29, 2019

For Weight Loss (Obesity/Overweight) "I purchased Contrave for weight loss and was so excited to try it after reading the reviews. After taking it for 1 week, I started having headaches and was nauseated. I continued taking the medication, hoping the side effects would go away, however, after 3 weeks, they were so bad I couldn't do it any longer. I stopped the medication for 1 week. After two weeks, I started feeling better, so I started back on the medication, but I took it at night hoping for better results. I woke up at 3 a.m. with a horrible headache, nauseated, and could not go to work the next day. I did not lose any weight while taking this medication, only lost time from employment."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.