Bupropion / naltrexone and Anxiety: What Users Say (Page 2)

• She...
• March 24, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I just took my first pill, literally 5 minutes ago. I have to say I'm terrified of the side effects, but at 56 years, only 5'1" and 230 pounds, I'm at my wits' end with my weight. I hope to be able to report back that I've had no side effects and that it's working. Reading all the reviews has helped. Fingers crossed it works! So after one week, I'm done. I can't take the jittery feeling, I almost fell at work yesterday. I was walking like I was drunk. Trying to get a normal sentence out was difficult, my mind was just not right. I lost 3 pounds, but I don't think it was the Contrave that did it. No other side effects though, just feeling like I was higher than a kite :("

• Ash...
• Taken for less than 1 month
• March 15, 2022

For Weight Loss (Obesity/Overweight) "The pandemic took a toll on my physical and mental health and well-being. In consultation with my family doctor, therapist, and weight loss doctor, I started bupropion 100 mg on March 1 and then, on March 8, added approximately 12.5 mg of naltrexone (1/4 of a 50 mg pill), to make the drug “Contrave.” This was given to me to aid in weight loss and also to aid in chronic anxiety/mild depression. Today is 3/15, and I have released 7.2 pounds so far and have a general sense of well-being that I haven’t felt in a while! When just on the Wellbutrin alone, at first I had a ton more energy throughout the day and could focus more but had more anxiety when I initially started it and realized I needed to cut out all caffeine. After cutting caffeine and adding naltrexone, my anxiety has diminished, and I haven’t had to take Xanax, nor have I had irrational thoughts like I was having prior to going on these drugs. I will continue to take the meds and update this accordingly."

• BBa...
• Taken for less than 1 month
• January 11, 2019

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I was rushed to the emergency room after taking Contrave. I experienced heart palpitations, anxiousness, nervousness, mild stomach cramps, and nausea. I was so sick I had to crawl to the door to have a neighbor take me to the hospital. This was not for me and hope that others don’t experience this reaction. I have never been this ill. I was administered medicine for nausea and given a shot that made me sleep drowsy."

• BBa...
• Taken for less than 1 month
• January 11, 2019

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I was rushed to the emergency room after taking Contrave. I experienced heart palpitations, anxiousness, nervousness, mild stomach cramps, and nausea. I was so sick I had to crawl to the door to have a neighbor take me to the hospital. This was not for me and hope that others don’t experience this reaction. I have never been this ill. I was administered medicine for nausea and given a shot that made me sleep drowsy."

• Sho...
• May 16, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I'm 34, started at 168 lbs, and am 5 ft tall. Week one, I had dizziness and really bad anxiety. Day 3 through 5, I thought I was going to pass out at work. I can't stay asleep. Week one, I lost 2 lbs. I'm on week 2. I increased to 2 pills on Saturday. Earlier today (Monday), my coworkers said I was acting weird, and I felt anxious again. I took my 2nd pill at 8 pm. It is now 5:20 am. I woke up at 2:45 feeling dizzy and very anxious, like panic attack anxious. I am tired, nauseated, and dizzy. I don't see how I'm supposed to go to work. I'm seriously considering going off this medicine. Pros: it really did cut out cravings, I eat a lot less, I drink more water, and it's easier to make better choices. Cons: anxiety, lightheadedness, dizziness, nausea, insomnia."

• Jac...
• Taken for 1 to 6 months
• March 6, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "So I have been taking these for 1 and a half months, 4 pills a day. The Good: I have to force myself to eat or I can go all day without eating. I have lost 20 lbs. Contrave has helped curb my alcohol addiction, which is helping with the weight loss. I have no trouble sleeping. The Bad: I've had to throw up a couple of times. I've had a few tummy aches, a little constipation, I have had a few headaches, but nothing too bad. Once I went up to 4 pills a day, I've noticed that I am a little jittery, more depressed, anxious, and for the last few days my chest has been hurting and I got a couple of sharp pains in my heart. So I'm dropping down to 3 pills a day. I don't want to stop taking the pills because they do work. If I don't feel any better, I will drop to 2 pills a day. I feel like I'm dehydrated all day! But this has made me have to drink a lot more water, which is also helping with the weight loss. I am really happy that I'm sleeping well during the night, I do get tired still during the day and have been taking naps."

• Jac...
• Taken for 1 to 6 months
• March 6, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "So I have been taking these for 1 and a half months, 4 pills a day. The Good: I have to force myself to eat or I can go all day without eating. I have lost 20 lbs. Contrave has helped curb my alcohol addiction, which is helping with the weight loss. I have no trouble sleeping. The Bad: I've had to throw up a couple of times. I've had a few tummy aches, a little constipation, I have had a few headaches, but nothing too bad. Once I went up to 4 pills a day, I've noticed that I am a little jittery, more depressed, anxious, and for the last few days my chest has been hurting and I got a couple of sharp pains in my heart. So I'm dropping down to 3 pills a day. I don't want to stop taking the pills because they do work. If I don't feel any better, I will drop to 2 pills a day. I feel like I'm dehydrated all day! But this has made me have to drink a lot more water, which is also helping with the weight loss. I am really happy that I'm sleeping well during the night, I do get tired still during the day and have been taking naps."

• Cyn...
• April 23, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am 33 years old, 5' 2" and weigh 230. I started taking Contrave 3 days ago. I took my first pill in the morning, and shortly after, I felt different. Then my mouth started getting dry. Throughout the day, I drank lots and lots of water, which is a plus because I am not a fan of water, and I felt very sleepy. On the second and third days, it was the same, but now this time I ate less-major plus-but my anxiety level was at my most high, and I just wanted to cry. I felt depressed. I spoke to my husband in regard to my side effects, and I just started to cry. I've read some reviews, and I see that it does work, but I am having second thoughts because I don't want to feel depressed."

• Jes...
• December 4, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I have been taking Contrave since August 18th, and today is December 4th, and I have had great success. If you feel a little funny for the first week or two, it is totally normal. Just a tiny bit jittery and a little constipation at first. It is all gone now. I originally started at 305 pounds and was able to get down to 275 pounds on my own. It took me a long time to lose my first 30 pounds, 6 months to be precise, I began to get discouraged. After talking to my doctor, he thought I would do well on Contrave. With Contrave, I have lost 40 pounds in less than 4 months. I don't have any side effects, and I feel great! This medicine is changing my life, and I am so grateful to have found it!"

• Ral...
• Taken for less than 1 month
• March 7, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Went to my doctor because I needed to lose 40 to 50 pounds. I have been on Contrave for three weeks and have lost six pounds. The only problem is my doc gave me Xanax, as this keeps me calm, as the Contrave makes me anxious. This medicine is not worth it. It makes me feel very wired. I guess I should have known when the Xanax was prescribed."

• Suz...
• Taken for less than 1 month
• April 17, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Just started a week ago and ended up taking 2 instead of one pill the first dose. Aside from being dizzy and jittery that first night, the only side effect I have noted is being very thirsty. My energy level is several times what it used to be, but it is not frantic or jittery. As far as mood, things seem to not be bothering me as much, which is great. I am a diabetic, and my numbers have been great, a couple of lows, but that is my fault for not eating... I have found that I have to force myself to eat, and while I still think about food, my cravings have greatly decreased. So far, down a pound a day."

• TXs...
• Taken for 1 to 6 months
• March 24, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am a 31-year-old female, 5'6" at 248 lbs. I have a thyroid issue and was struggling to lose weight. My doctor prescribed me Contrave to see if it would help kick start my weight loss (lost 15 lbs previously but had plateaued). I had high hopes for Contrave, but after a month and a half, I'm done. It immediately made me feel shaky and jittery. I tried stretching out the increase in pills, but it didn't seem to make a difference. I got up to 4 pills/day, but other than not eating as much, I haven't lost any weight. I actually gained a couple of lbs. However, the worst side effect was the constipation. I tried taking fiber pills, eating lots of vegetables, etc., and nothing helped. I even tried a laxative, which helped some. I felt miserable!"

• soc...
• September 4, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am a 52-year-old female, 5'7", 175 lbs. Ideal weight 135 lbs. 2 years ago, 148 lbs, but it took 4 hours a day in the gym, 6 days a week. Started Contrave 3 weeks ago at 175 lbs. Week 1: horrible taste, very spaced out, up and down sleep. No weight loss. Week 2: bad taste, nose plugged up, making breathing difficult. extreme spaced out, no sleep, increased energy. 2 lbs weight loss. Week 3: I could only follow this dose for 2 days. My nose was better, taste still off, can't sleep, so anxious that I thought I could crawl out of my skin (not kidding). I couldn't even drive to work without feeling like I needed to get out of the car. On the 3rd day of week 3, I went back to 1 pill in the morning and 1 pill in the evening. I'm staying there until my doctor's appointment. This drug is no joke! I wish I could continue the way prescribed. I will update after speaking with my doctor. Good luck to anyone trying this, hope you have a better experience."

• Emi...
• April 23, 2016

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am 2 days shy of the full dose. I've been on Contrave for just about 3 weeks. My take: I've lost 10 lbs so far. My depression is now very well-controlled - I am on Viibryd, which affects serotonin, and to add Contrave's effects on norepinephrine and dopamine means I have felt almost no depression, very serene (most of the time). Some bowel side effects, which Miralax really helped. No craving for fatty, fast food. Almost no alcohol craving. Throwing up if I did combine fatty food and alcohol. Low appetite - only eat when really hungry. Has not helped my anxiety. Bottom line? I feel better than ever, am completely hopeful for continued success on Contrave, and I would recommend it to everyone!!"

• AB8...
• October 28, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "This medication has been miraculous for me so far! Just started 2 days ago. Very mild side effects, only a bit jittery in the morning and felt kinda spacey day 1. I feel in control again. I feel calmer and almost tearful at the hope this continues. I'm no longer obsessed with food. So happy my doctor suggested this. I have a lap band but regained 50 pounds the past 2 years. I feel empowered to get to my goal weight again! I'm eating healthy choices now, loving vegetables and fruit! Was eating 2 candy bars daily... now have 0 cravings for sweets! Buying a really nice bicycle soon and plan to ride 5 times a week! Good luck to everyone!"

• Jul...
• Taken for less than 1 month
• September 6, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am a 38-year-old female with PCOS. Having PCOS has always made losing weight difficult but doable. However, since my last pregnancy with twins, it has been 10x harder. My starting weight is 198.8 as of this morning before breakfast. I am 5'5'' tall. My doctor has me taking one pill once a day for week 1, one pill twice a day week 2, three pills daily-2 morning, 1 night for week 3, and 4 pills daily as 2 morning, 2 night for week 4. I don't take any other medication. I took my first pill this morning after eating breakfast. A couple of minor stomach cramps and a little jittery (getting close to my normal lunchtime), but no other side effects as of now. I will check back in weekly with updates."

• Gra...
• May 31, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I'm a 65-year-old woman, 5'9", and I weighed 193 lb, with very high cholesterol, when I started Contrave about a month ago. My goal weight is 160 lb. So far, I have lost about 12 lbs. Contrave has been very helpful in controlling my cravings for treats. It has been easy to stick with healthy foods, such as salads, yogurt, etc. I am only taking 3 tabs a day. When I took the full 4 a day, it made me a bit jittery. I found when I took 4, it also made my ears ring. So I take one first thing in the am, one at around 11 am, then one at 3:30 pm. This minimizes the side effects. When I eat dinner, halfway through, I suddenly get nauseous, so it makes me literally stop eating. I take this as a sign that I have had enough to eat. Then I really have no interest in eating anything else later, where normally I'd be looking for ice cream. I would recommend trying Contrave... I'm really glad I'm doing this as it is helping me a lot."

• cra...
• Taken for less than 1 month
• March 18, 2017

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am in the middle of week 3. I have lost 11 pounds and am thrilled. I had no side effects except a little constipation. I was feeling great. Then, 2 days ago, I noticed my jaw clenching up. I felt like I was grinding my teeth. Then, the last time I had this happen to me, I was on Bupropion. Same drug in this Contrave. By the next day, I was feeling jittery, clenched jaw, and a little spacey. Not feeling quite right at all. Kind of nervous and almost feeling like I shouldn't be driving. If I was busy, I didn't notice it. But when I was still, it was terrible. I am so sad, I think I am going to have to quit taking it. I have had such good results, and it was really helping me with my cravings. I just was not hungry."

• Gee...
• Taken for less than 1 month
• August 30, 2021

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "Day 1, took with breakfast and literally almost called 911. I had an overwhelming sense of paranoia, extreme anxiety, and trouble breathing, but maybe due to the anxiety. Felt nauseous and a floaty feeling. Nope, not for me."

• Ann...
• Taken for less than 1 month
• April 4, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I’m on day 5 now of taking one pill, and I just cannot tolerate this medication. I feel high as a kite and awful: very anxious, highly medicated, as if I’m on speed, extremely tense, and disoriented. Yes, my appetite is well under control, but I feel barely human at this point. I feel like I’ve been hit with a ton of bricks."

• Ann...
• Taken for less than 1 month
• April 4, 2018

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I’m on day 5 now of taking one pill, and I just cannot tolerate this medication. I feel high as a kite and awful: very anxious, highly medicated, as if I’m on speed, extremely tense, and disoriented. Yes, my appetite is well under control, but I feel barely human at this point. I feel like I’ve been hit with a ton of bricks."

• Sie...
• Taken for 1 to 6 months
• January 2, 2016

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "On for 9 weeks. Started dose gradually as prescribed, 2 days I had constant diarrhea. Immediately, my cravings were gone for sugar and chocolate, but keep reading! At full dose (2 am, 2 pm), I had constipation, got better after taking Colace. I felt fine all day and night, but when the evening dose had worn off by the am, I would wake up shaking and heart racing. Felt better after the next dose, but shaky all day. One day I almost passed out after normal exercise. Then non-stop nausea set in, so now I could not eat and felt like vomiting just from looking at food! Drug made me anxious and jittery, so I stopped it. Lost weight...20 pounds in 9 weeks, mostly because of nausea, but side effects were not worth the weight loss."

• Sie...
• Taken for 1 to 6 months
• January 2, 2016

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "On for 9 weeks. Started dose gradually as prescribed, 2 days I had constant diarrhea. Immediately, my cravings were gone for sugar and chocolate, but keep reading! At full dose (2 am, 2 pm), I had constipation, got better after taking Colace. I felt fine all day and night, but when the evening dose had worn off by the am, I would wake up shaking and heart racing. Felt better after the next dose, but shaky all day. One day I almost passed out after normal exercise. Then non-stop nausea set in, so now I could not eat and felt like vomiting just from looking at food! Drug made me anxious and jittery, so I stopped it. Lost weight...20 pounds in 9 weeks, mostly because of nausea, but side effects were not worth the weight loss."

• Anonymous
• October 18, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I only took 1 tablet for two days and felt tired but jittery, difficulty swallowing, and insomnia. I did lose 2 pounds but stopped taking it because of the way it made me feel. Can anyone tell me if those feelings go away after longer use?"

• Jnb...
• July 6, 2015

Bupropion / naltrexone for Weight Loss (Obesity/Overweight) "I am on week three of Contrave. I've had some side effects with the drug, including feeling short of breath and a little more anxious than normal, not all the time but more than normal. I had nausea the first day. I have had headaches off and on. I have lost 7 pounds, but with the side effects I've been experiencing, I'm no longer going to continue the drug. Feeling anxious and short of breath is just not a good combo. If I wasn't experiencing these things, I would applaud the drug, for it has stopped my appetite."