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Epiduo and Irritation: What Users Say (Page 2)

Reviews for Epiduo

Commonly mentioned side effects
  • Abi...
  • Taken for less than 1 month
  • August 22, 2017

For Acne "I had fairly mild acne, but when I went to the doctor, it had been flaring up and looked quite bacterial. When I first started using it, I was happy, as it appeared to clear up my spots in less than a week, but after maybe the third use (I was using it once per night), I noticed my skin was very dry, but was not too worried, as this is a known side effect. Unfortunately, the dryness only got worse, even when I used it after moisturizer, and even stopped using it. It got to the point where my skin was so dry and irritated that it was bright red, and I could barely splash water on my face without it stinging. If I used cleanser, my face would sting so badly I cried. It took 3 weeks to clear up, and I was left with chemically burnt skin."

1 / 10
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  • Anonymous
  • January 2, 2010

For Acne "I am in the first week of using it, and I have a lot of irritation, and my skin is very dry. I didn't have much acne before, and I have a lot now. Putting a lot of lotion helps the dryness, but I am in need of the bumps to leave."

1 / 10
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  • Ali...
  • May 16, 2016

For Acne "I am 37 and never had acne until 7 months ago. Pimples on my jawline and forehead with acne scars started to wear on my self-esteem. I've been using Epiduo for 5 days and can already see an improvement. I purchased a mild facial wash, toner, and moisturizer with SPF 20 from Clinique to use while I'm in treatment. No irritation, flaking, or burning, just clearer skin and the scars are starting to fade already. I use my normal skin regimen in the AM and the Epiduo at night. I love this product."

9 / 10
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  • Anonymous
  • January 18, 2011

For Acne "I have been using Epiduo for a month now and have had acne for a few years. It is great at getting rid of the acne, but the side effects are bad on me. It made my eye swell up and go red and cause major irritation. When I go back to my dermatologist, I will ask to be put on something else."

3 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 26, 2015

For Acne "I am a female in her mid-20s. I've always had random breakouts due to hormonal changes and stress. Recently, my acne seemed to be getting out of hand, and none of the at-home treatments I was using helped. I have been using Epiduo for a little over 3 weeks now, and I think my skin is just now getting used to it. At first, it really irritated my skin and caused it to burn, become red, and look swollen. I have not experienced any peeling like most other people have. I have to experiment with it a little bit, though. I just apply it to my forehead and chin, then bring the excess onto my nose. I use Cetaphil daily moisturizer for dry skin on top of the Epiduo. For the past week, my skin has been exceptionally clear and not nearly as irritated."

8 / 10
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  • Eli...
  • February 10, 2015

For Acne "I recommend Epiduo for people with oily skin. For the most part, Epiduo is a very harsh treatment that dries out and irritates the skin. It didn't really help my acne, but it might've if I had oily skin."

6 / 10
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  • Ros...
  • Taken for 1 to 6 months
  • January 1, 2021

For Acne "I am 21 and recently started getting acne breakouts. Looking back on pictures of the first ones I got, they really weren't bad, but I called the doctor as I had heard about Epiduo and got a prescription over the phone (he hadn't actually seen my skin). I have now been using it for about 3 months, and it is now SO bad, so, so, so much worse than it was at the beginning. I know it is supposed to purge your skin, but from reading around, I think if your skin is quite sensitive to it and becomes irritated, it can actually make the acne worse and prevent it from healing. To be honest, I WISH I had never started using this cream in the first place. Won't be the same for everyone, I'm sure, but just be careful with this product!! As I will almost definitely now get acne scarring, and who knows if/when it will clear up."

2 / 10
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  • Kim...
  • Taken for 5 to 10 years
  • May 14, 2016

For Acne "It works!!!! I have been battling with acne for years. I am 35 years old, and I have been using Epiduo for over 6 or more years, and I can say it's a life-saver. A little redness and irritation is nothing to complain about, the results are great."

10 / 10
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  • Mck...
  • January 7, 2017

For Acne "This made my skin incredibly sensitive and irritated all the time, it dried out my cheeks and nose. It didn't get rid of hardly any acne. I have to stop using it after only about 2 months of use due to the sensitivity."

3 / 10
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  • Mol...
  • Taken for 1 to 6 months
  • August 26, 2016

For Acne "At the age of 24, I unfortunately developed severe acne on my lower face. Tried everything the dermo suggested, antibiotics. Some prescribed creams, then Epiduo. Doctor told me I'd have some irritation, dryness, redness and my acne might get worse before it got better for a few weeks. So for 12 weeks, I patiently followed the doctor's directions using the suggested cleanser, moisturizer for the dryness and my nightly pea-sized application of Epiduo. This product, *sigh* made my acne WORSE for 12 weeks! More painful deep zits, bigger pores, more outbreaks. Like I didn't even go out anymore, it was so bad. I quit using it from frustration and oddly my acne cleared up 90%. Maybe I had a reaction? Who knows."

1 / 10
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  • Jes...
  • Taken for 1 to 6 months
  • June 20, 2014

For Acne "I've been using Epiduo for two months now and it doesn't help at all. It burns my skin and dries it out so badly! It gets flaky, red, and very irritated. It feels like a horrible sunburn and it looks like you take horrible care of your skin. It stings to put anything on it, even water. It does do its job though, dries out the acne. But I still see the redness or dark brownness of the acne. It's so annoying, ugh."

5 / 10
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  • Raf...
  • October 16, 2011

For Acne "My skin got really better, got some irritation earlier, stopped using it and resumed the treatment again. Works!"

9 / 10
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  • Van...
  • August 20, 2017

For Acne "Definitely, this helped me treat my acne. It cleared out the skin gradually, and I didn't have any irritation or redness with it."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.