Acyclovir topical and Blisters: What Users Say

• Ama...
• Taken for 5 to 10 years
• March 2, 2018

Acyclovir topical for Cold Sores "Zovirax cream is amazing. I hardly ever get an actual cold sore anymore because I apply the cream as soon as I feel any tingle, and it prevents the outbreak. Well, 3 days ago, I missed the tingle because I had a huge pimple forming on my chin, just under my lip, and it was so painful that it masked the tingle on my lip. By the time I woke up and realized what was happening, my lip had already swollen quite badly. I was horrified and thought the battle was already lost, but I immediately started applying Zovirax. My lip still swelled up to 3 times its size over the next 36 hours, but then it started to recede and never even blistered! It is now 3 days after it started, and my lip is almost back to normal. I cannot believe it worked when the cold sore had already taken hold and stopped the blisters from erupting. I love this stuff so much! It cost about $80 for a 5g tube the last time I bought it, but it lasts a long time for me. I always carry it in my purse, so I am armed for battle."

• Anonymous
• December 15, 2009

"This medication helps the breakout a lot, makes it smaller, less noticeable. One thing I have noticed though, is when the first lesion is on its scabbing stage, I get little, tiny blisters around or near the first site. Feels like I am starting to get more cold sores. They never seem to go deep or actually scab up. But still, it's annoying when you think your cold sore is going away, then you start feeling more tingles. Just my feedback."

• AW8...
• Taken for less than 1 month
• January 3, 2023

Acyclovir topical for Cold Sores "I have always suffered with cold sores (female, mid-30s, UK) and even as a child, when my mum would buy me Zovirax, I knew it made them feel worse than if I just left well alone. Therefore, I have avoided it for 20 years. However, over Christmas, I caught strep and was very run down and started to get swollen lips (always my first sign). The doctor strongly suggested getting some Zovirax urgently to prevent spread. Within hours of applying, the sores had spread and tripled in size. Cut to a week later, both my nose and bottom lip have blistered like I have touched fire, have filled with pus and scabbed, and feel extremely numb. I will never use the product again. I will be left with scarring."

• d m...
• Taken for less than 1 month
• May 4, 2023

Acyclovir topical for Cold Sores "I am from the UK but was given Zovirax cream for a cold sore while in Spain. This caused the cold sore to blister and spread. The skin surrounding my mouth also burned and blistered. Will never use again. Absolutely awful experience. Skin still not healed a month after use. Will stick with Blistex in the future."