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Acetaminophen / hydrocodone and Drowsiness: What Users Say (Page 2)

Brand names: Xodol Zyfrel

Reviews for Acetaminophen / hydrocodone

Commonly mentioned side effects
  • Mar...
  • Taken for 1 to 2 years
  • July 31, 2019

For Pain "Like others mentioned, all 10/325s are not the same. Mallinckrodt M367 helps somewhat with pain, but just one tab keeps me so groggy I don't feel like getting up and doing anything. Almost like it has a sleeping ingredient in it. Unfortunately, that's all my big chain pharmacy carries. Seems like all of them carry this garbage. I can't recall the brand, but yellow oblong ones, Z on one side, some numbers on the other side worked great. Little side effects. Pharmacy those came from switched to another, but it's not Mallinckrodt, so maybe it will be better."

2 / 10
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  • Anonymous
  • October 19, 2020

Acetaminophen / hydrocodone for Back Pain "I was on Norco over 10 years, seems all it began to do was make me sleep. Dr. switched me to Percocet 10 mg, better at alleviating pain but still causes sleepiness. He switched me to oxycodone 10 mg, seems to work better for me."

7 / 10
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19 Report
  • Rac...
  • Taken for 1 to 6 months
  • January 18, 2021

For Pain "I've been taking this hydrocodone 10 for over 12 years now, and last month, my pharmacy gave me a generic brand made by a company called West. This didn't do anything to help with my pain, but I can tell you what it caused. I started to have gallbladder and liver issues. I also couldn't move my bowels almost all month. Not to mention the constant sick feeling and falling asleep all day and night. Two days ago, I went for my refill, and I got the same kind I used to get before this last time, and within the last two days, my liver and gallbladder are no longer hurting, I don't have that sick feeling, and I can stay awake all day now."

1 / 10
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16 Report
  • lyn...
  • Taken for less than 1 month
  • March 1, 2016

Acetaminophen / hydrocodone for Pain "This medication did not help my pain post-surgery. My doctor had to change me to Percocet after 2 weeks. I even tried taking 2 at a time, with no relief. It was like there was no effect at all; I did not get drowsy, so it did not help me sleep. It did not give me the jitters or a 'high' feeling. I cannot see how anyone would take these for recreational use or get addicted. They do absolutely nothing."

2 / 10
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39 Report
  • Lim...
  • Taken for less than 1 month
  • October 17, 2019

For Pain "I just had hip replacement surgery a few days ago, and they prescribed hydro/acetam 7.5/325. I was hoping for some real pain relief as it's a pretty invasive surgery. These were generic and came from 'Aurobindo.' Initially, it provided a little relief, but I mostly took it because it made me drowsy and helped me sleep. It never really helped with the pain, and after a few days, didn't even make me drowsy. I took 2 on a Sunday night, and it was a nightmare. No reason to take it if it didn't help, so I stopped cold turkey, and that was a nightmare after only 6 days. This was supposed to be a powerful pain reliever, so I was just taking 1 every few hours, but there was no noticeable relief. My hip has always hurt, so I just grunted through the pain knowing it would improve. Jelly beans would have been as effective."

1 / 10
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  • Wil...
  • February 17, 2017

Acetaminophen / hydrocodone for Pain "I was prescribed Norco 5/325 to manage post-operative pain from a tooth extraction. The first time I took it, I took one pill, became really nauseous, and didn't feel any pain relief. The second time I took 2 pills. I didn't develop nausea, which was good, but I also didn't experience any pain relief or drowsiness. It was like I hadn't taken anything at all."

1 / 10
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  • Jay...
  • Taken for 1 to 6 months
  • April 28, 2017

For Back Pain "I take 5/325 for lower back pain caused by degenerative disk disease. The hydrocodone/acetaminophen mix works wonderfully, but I find that the pain relief only lasts an hour or two before it begins to come back with a vengeance. It's great to have around for quick pain relief, it is not addictive, despite what a lot of doctors say. I take two a day to control my lower back pain, and I've never had a problem stopping immediately for any reason. I also take tramadol 50 mg to help relax the muscles, but the tramadol makes me really groggy, whereas the hydrocodone does not. The hydrocodone does cause me to be up at night, but I am able to manage that, and it is worth the pain relief. Highly recommend. Hard to get, however, doctors don't like prescribing."

6 / 10
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  • Anonymous
  • March 24, 2009

Acetaminophen / hydrocodone for Pain "I had 2 foot surgeries within 9 months of each other that took me over 2 years to heal and was given Vicodin for the pain. At first, it was awesome, it took care of the pain, but I slept all the time. After a while, I ended up taking more to relieve the pain, which scared me. So I would go off of it for a month or so and live in agony to prove I was not addicted. It detaches you from what's going on around you. I finally figured out that I would rather be in some pain than be so depressed as that drug made me feel. I just stick to ibuprofen now."

6 / 10
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  • Bru...
  • December 5, 2009

Acetaminophen / hydrocodone for Pain "This is a good pain medication, however, there are side effects. As with any opiate, the drug can and usually does cause dependency. Long period use is extremely hard on the liver due to the high levels of acetaminophen. Some people experience drowsiness, while others experience insomnia. On a scale of 1 to 10, the pain in my personal experiences will be reduced from a 10 to a 5 in approximately 30 minutes. I recommend speaking with your doctor about alternatives if you are going to be treated in the long term."

7 / 10
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  • zen...
  • August 22, 2013

Acetaminophen / hydrocodone for Back Pain "Fractured and wedged connecting vertebrae put on the 5s for many years. Now, with another injury to the back, moved to the 7s. The first time taking the 5s made me drowsy for a couple of weeks, but nothing since. Does its job."

9 / 10
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  • rho...
  • October 5, 2009

Acetaminophen / hydrocodone for Pain "I took this for degenerative disc disease when Percocet stopped working. It helped me as much as Percocet. It was slightly more sedating than Percocet, but at the same time, it helped me rest better. I am not currently on pain pills, but if I had to have any, and had an option, it would probably be Lortab 10."

9 / 10
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  • sop...
  • Taken for less than 1 month
  • December 25, 2016

For Pain "I suffer from chronic pain and take an extended, longer-acting opiate pain med (methadone 10 mg). However, I had a dental abscess on the 23rd and was RX'd hydrocodone/acet 10-325 in the emergency room, and it worked wonderfully. The methadone works well for chronic everyday pain, but when sharp, acute pain such as a toothache, earache, or any kind of acute pain occurs, the Norco (hydrocodone 10/325) knocks the edge right off of it. No tiredness, grogginess, just fast pain relief. I was also RX'd hydrocodone 7.5/650 (Vicodin ES) a long time ago, and I remember it worked well then too."

10 / 10
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  • Sin...
  • May 3, 2009

Acetaminophen / hydrocodone for Pain "I've just recently had 19 teeth pulled all at once and absolutely couldn't sleep at night. I was given 750 mg of Vicodin (Hydrocodone), and now I can sleep. It takes the pain away but only lasts for 3 hours at the most. I sometimes get a headache from it and have suffered from constipation. All in all, the relief you feel from severe pain is well worth it. Do not drive while taking this medication. It makes some people sleepy and slows down your reaction time."

7 / 10
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  • Anonymous
  • December 2, 2009

Acetaminophen / hydrocodone for Pain "I have been taking this drug for the last couple of months for severe shoulder pain, neck pain, and upper back pain... due to a recent auto accident... I had whiplash, a pinched nerve in my neck, and nerve damage in my shoulder, and it seems to work amazingly to ease pain that is sometimes so unbearable it hurts to move my head. I haven't experienced any bad side effects except for the occasional drowsiness and loopy feeling, but the benefits definitely outweigh that, and I'd recommend this medicine to anyone in severe pain. As everyone else has said, use with caution and take only as needed per doctor's orders. Don't know how I would have or would be functioning now without this drug and Zanaflex."

9 / 10
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  • Anonymous
  • July 27, 2010

Acetaminophen / hydrocodone for Pain "I was prescribed Vicodin to control pain when I got my wisdom teeth taken out, and thank goodness I was. This medicine literally takes away all of my pain, which is unusual because I am very sensitive towards teeth/mouth pain. My only complaint is that about 20 minutes after I take the pill, I literally cannot do anything. I have to lay with my eyes closed because I am literally incapable of doing anything else. But if this side effect is the worst that I get (which is so far the only side effect), it is a small price to pay for all of my mouth pain to be gone. I would recommend this."

10 / 10
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  • roo...
  • Taken for 1 to 6 months
  • August 3, 2012

For Pain "I have two fractured vertebrae from a car wreck. At first, my Dr. prescribed me Percocet 5/325, it worked, but for me, the side effects (nausea, itching, and sleeplessness) were awful. He then switched me to Lortab 7.5/500, and wow! Not only is the pain-killing effectiveness just as strong (if not stronger) than the Percocet, but I have experienced NOT ONE negative side effect."

9 / 10
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  • kri...
  • February 5, 2010

Acetaminophen / hydrocodone for Pain "Had back surgery in May 2009, and due to scar tissue, I have chronic pain. Working now with a pain management specialist and taking Lortab. It does help alleviate the pain, but I only take it when I have to. The only side effect for me is a little sleepiness."

9 / 10
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7 Report
  • roo...
  • Taken for 1 to 6 months
  • August 2, 2012

For Back Pain "I fractured two vertebrae in a car accident last month. At first, I was prescribed Percocet 5/325, but for me, the side effects (nausea, itching, sleeplessness) were not worth it. So my Dr. switched me to Vicodin 7.5/500, and wow! There were no negative side effects, and the pain relief was good."

8 / 10
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3 Report
  • Anonymous
  • October 30, 2008

For Pain "After having maxed out on the highest dose of tramadol (Ultram), my doctor offered me this. It is good for my spinal arthritis pain. I am doing more daily tasks than in a long time. But in 1 week now, I sometimes have to fight grogginess most of the day and would only consider driving if I absolutely had to. Half a tablet makes me feel stoned, and I take the smallest dose. I did take this after my gallbladder surgery, and it was very good."

8 / 10
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3 Report
  • Anonymous
  • October 30, 2008

For Pain "After having maxed out on the highest dose of tramadol (Ultram), my doctor offered me this. It is good for my spinal arthritis pain. I am doing more daily tasks than in a long time. But in 1 week now, I sometimes have to fight grogginess most of the day and would only consider driving if I absolutely had to. Half a tablet makes me feel stoned, and I take the smallest dose. I did take this after my gallbladder surgery, and it was very good."

8 / 10
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3 Report
  • Anonymous
  • January 29, 2013

For Pain "I have no history of 'bad health,' and being a 20-year-old female, I was shocked to find I had kidney stones. The pain was horrible and unbearable! I was given hydrocodone-acetaminophen, and literally within 8 to 10 minutes, the pain was no longer there! You do feel a bit drowsy in my case, but pain-free."

9 / 10
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6 Report
  • Anonymous
  • February 12, 2009

Acetaminophen / hydrocodone for Pain "I was prescribed Lortab for pain due to an infected tooth. I do not feel it helped the pain at all. The only thing that it definitely does is help me fall asleep. I am still in pain waiting for the antibiotics to clear up the infection so I can get a root canal. I haven't got the same results as the people who consider this magical. I really wish it was like that for me."

2 / 10
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10 Report
  • Anonymous
  • December 1, 2009

Acetaminophen / hydrocodone for Pain "Diagnosed with carpal tunnel syndrome, my physician prescribed two Vicodin a day for pain relief. For the first couple of days, I was drowsy after the noon tablet, but now my body seems to have acclimated itself to the drug, and I'm no longer drowsy, and I'm reasonably pain-free. It isn't perfect, but I gave it an eight out of a possible ten! I don't expect to be on it long enough to worry about addiction."

8 / 10
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  • hom...
  • Taken for less than 1 month
  • March 29, 2017

For Pain "In my travels, I keep a couple of combo acetaminophen/codeine derivative pills available, in the case of either diarrhea or sleeplessness. I use it very sparingly and never combine it with alcoholic drinks. Quite satisfactory--worth toting around. Long shelf life, apparently."

8 / 10
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  • Sus...
  • Taken for 6 months to 1 year
  • August 9, 2019

For Pain "I have been taking Norco 10/325 1-2 tabs (generic) for about a year. I have had great results in controlling my pain. Being an RN, I already knew that this medication has the side effect of causing drowsiness. I usually take it at bedtime to control pain so I can sleep. This is not categorized as a sleeping agent, however, any drug like this that has a narcotic in it can make one drowsy."

10 / 10
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14 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.