Protox To Present Interim Prostate Cancer Data at AUA Conference
VANCOUVER, British Columbia, Sept. 6, 2007 /CNW/ - Protox
Therapeutics Inc. (TSX-V:PRX) today announced that interim
data from the recently completed Phase 1 clinical study
testing PRX302 in patients with locally recurrent prostate cancer
following radiation failure will be presented at the American
Urological Association ("AUA") South Central Section Annual
Meeting. The conference will take place at the Broadmoor Hotel
in Colarado Springs,
Scott Coffield, M.D., Principal Investigator from the lead site at Scott and White Memorial Hospital, will present the data on Friday, September 7, 2007. The presentation, entitled "Interim Results of a Phase 1 Clinical Study for the Transperineal Intraprostatic Administration of PRX302 (PSA-PAH1) in Patients with Locally Recurrent Prostate Cancer" indicates that PRX302 is safe and well tolerated in patients and that it shows encouraging signs of therapeutic activity.
PRX302 is rationally designed to kill prostate cancer and hyperplastic cells that over-produce the enzyme prostate specific antigen (PSA). Patient enrollment has been completed for this Phase 1 study and top-line results were released in July indicating that PRX302 is safe and well tolerated and that a maximum tolerated dose was not reached in the study while encouraging signs of therapeutic activity were observed. Plans are currently underway to commence a Phase 2 study before the end of the year.
Protox Therapeutics is a leader in advancing novel, targeted protein toxin therapeutics for the treatment of cancer and other proliferative diseases. The company is actively developing two distinct but complementary platforms, INxin(TM) and PORxin(TM), and currently has four clinical programs in development. A Phase 2a clinical trial into the use of PRX321 (INxin) for the treatment of primary brain cancer has been completed and the drug has received Fast Track Designation and Orphan Drug Status from the US FDA. In addition, a Phase 1 trial has been completed for PRX321 to treat patients with renal cell carcinoma and non-small cell lung cancer. Patient enrollment has been completed for a Phase 1 clinical trial into the use of PRX302 (PORxin) for the treatment of localized prostate cancer. A Phase 1 clinical study of PRX302 for the treatment of benign prostatic hyperplasia (enlarged prostate) is ongoing.
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unknown risks, uncertainties and other factors that may cause
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therefore these statements should not be read as guarantees of
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relate to, among other things, anticipated financial
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events or otherwise.
For further information: James Beesley, Director, Investor Relations, Protox Therapeutics, (604) 688-0199, firstname.lastname@example.org; Michael Moore, Investor Relations, Equicom Group, (416) 815-0700 x 241, email@example.com
Posted: September 2007