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Chinese Study Finds No Association between BPA and Diabetes in Large Scale Clinical Trial

NAMPA Lauds Latest Research on BPA and Diabetes; Study Refutes Previous Science in Several Key Areas

WASHINGTON--(BUSINESS WIRE)--Oct 27, 2011 - A new, large-scale study of human exposure to bisphenol A (BPA) -- Relationship of Urinary Bisphenol A Concentration to Risk for Prevalent Type 2 Diabetes in Chinese Adults (Ning et al., 2011) -- did not find an association between urinary levels and type 2 diabetes. The latest study analyzed urine samples from 3,423 Chinese residents using multivariable analyses and found no association between BPA levels and type 2 diabetes.

“This robust, cross-sectional study set out to confirm a previously reported association -- yet the data showed that there was no such association. The work by Ning refutes the findings by Lang, the only study that showed an association between BPA exposure and risk of diabetes,” said Dr. John M. Rost, chairman of the North American Metal Packaging Alliance, Inc. (NAMPA). “The Ning research is a more scientifically robust study, in design and population. Once again we see that when certain findings on BPA are subject to more robust clinical studies, we learn that those supposed health effects cannot be replicated. This is critical when regulatory agencies are considering the safety of BPA.”

“It is my hope that the results of the Ning study will prompt a more reasoned and thoughtful look at BPA, instead of a rush to judgment based solely on emotion,” Dr. Rost continued. “What this research tells us is that it is not enough to rely on one-time analysis and parental questionnaires to assess the impact of BPA; such studies are severely limited and their findings often do not hold up under the scrutiny of clinical testing.”

The conduct of the Ning study differed in two important ways from the previous, hypothesis-driven study. The Ning study's larger study population minimized bias in epidemiological analysis -- a concern with Lang and other studies that have utilized the National Health and Nutrition Examination Survey (NHANES) data. The Ning study also uncovered a flawed assumption used in the data analysis of the Lang study, which incorrectly indicated a relationship between BPA and the risk for diabetes.

The full study is available at


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Contact: North American Metal Packaging Alliance, Inc.
Michelle Lancaster, 202-223-4933



Posted: October 2011