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Absorption Systems to Present at the Combined 2010 American Association of Pharmaceutical Scientists and Pharmaceutical Sciences World Congress Meeting

Absorption Systems Sponsoring Forum Discussing BCS and BDDCS in Biowaivers in Addition to Presenting Nine Posters

EXTON, Pa.--(BUSINESS WIRE)--Nov 9, 2010 - Absorption Systems, a leader in testing drugs for ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity), today announced that the company will be presenting nine posters during this year's combined Pharmaceutical Sciences World Congress (PSWC) and American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition being held November 14-18, 2010 in New Orleans, Louisiana. This is the first time that these meetings will be held together with the theme “Improving Global Health Through Advances in Pharmaceutical Sciences.”

In addition to the nine poster presentations, Absorption Systems will be sponsoring an open forum entitled, “The BCS, BDDCS and Regulatory Guidances,” on Thursday, November 18, 2010 from 1:30 to 5:00 p.m. The open forum will provide current thinking on and better understanding of the regulatory application of the Biopharmaceutics Classification System (BCS) and the Biopharmaceutics and Drug Disposition Classification System (BDDCS) in biowaivers.

“AAPS and PSWC are regarded as the premier forums in pharmaceutical sciences,” said Patrick M. Dentinger, President and CEO of Absorption Systems. “We are excited to be a part of this historic combined meeting as both a presenter and sponsor. We are also pleased to share our research with the scientific community highlighting the significant progress we are making in understanding the ADMET properties of small-molecule drugs.”

The poster presentations and dates/times are as follows:

Monday, November 15th from 1 p.m. - 5 p.m.:
Poly(alkylcyanacrylate) Nanocapsules with Silica Core (Poster #M1349)
Author: Svitlana Silchenko, et al.

Tuesday, November 16th from 8 a.m. - 12 p.m.:
In Vitro and In Vivo Rabbit Models of Ocular Drug Absorption (Poster #T2086)
Author: Fany Guerra, et al.

Evaluation of Corneal Orbs Created from Human Stem Cells as an In Vitro Model for Studying Ocular Drug Absorption (Poster #T2085)
Author: Fany Guerra, et al.

Tuesday, November 16th from 1 p.m. - 5 p.m.:
Use of Caco-2 Knockdown Cells to Investigate Transporter-Mediated Efflux of Statin Drugs (Poster #T3371)
Author: Donna Volpe, et al.

Induction of Breast Cancer Resistance Protein (BCRP) and Enhanced Transport of Estrone-3-sulfate and Pheophorbide A Across Caco-2 Cell Monolayers (Poster #T3408)
Author: Wei Zhang, et al.

Determination of Substrate Specificity and Relative Activity of Uptake and Efflux Transporters in a New Cell Line: OATP1B1-Transfected MDR1-MDCK Cells (Poster #T3407)
Author: Wei Zhang, et al.

Determination of BCRP Activity and Evaluation of Potential BCRP-Mediated Drug-Drug Interactions in Caco-2 Cells Using the Fluorescent Substrate Pheophorbide A (Poster #T2392)
Author: Ying Wang, et al.

Wednesday, November 17th from 8 a.m. - 12 p.m.:
Determination of Red Blood Cell Partitioning and Whole Blood to Plasma Ratio Using Human, Rat, and Mouse Blood: Methods, Model Compounds and Species Differences (Poster #W4305)
Author: Zhiming Wen, et al.

Enzyme Kinetics of UGT Probe Substrates and Inhibitory Profile of Known Chemical Inhibitors for Six Major UGT Enzyme Activities Using Recombinant Human UGT Enzymes (Poster #W4306)
Author: Zhiming Wen, et al.

About Absorption Systems

Absorption Systems, founded in 1996, assists pharmaceutical, biotechnology and medical device companies in identifying and overcoming ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) barriers in the development of drugs, biologics and medical devices. The company's mission is to continually develop innovative research tools that can be used to accurately predict human outcomes or to explain unanticipated human outcomes when they occur. The CellPort Technologies® platform, a suite of human cell-based tests systems for drug transporter characterization, exemplifies Absorption Systems' commitment to innovation and is soon to be an industry assay standard for in vitro drug interaction assessment. Absorption Systems has facilities near Philadelphia, PA, and in San Diego, CA, and serves customers throughout the world. For information on the company's comprehensive contract services and applied research programs, please visit


Contact: Absorption Systems
Audrey Sarsfield, 1-610-280-1452
Schwartz Communications
Brianne Donahue or Wendy Mejia, 1-781-684-0770


Posted: November 2010