Generic Name: Linezolid Injection (lin AYZ oh lid)
Brand Name: Zyvox
Medically reviewed on Sep 5, 2018
Uses of Zyvox:
- It is used to treat bacterial infections.
What do I need to tell my doctor BEFORE I take Zyvox?
- If you have an allergy to linezolid or any other part of Zyvox (linezolid injection).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have an adrenal gland tumor called pheochromocytoma.
- If you have overactive thyroid disease.
- If you have high blood pressure.
- If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days. Taking Zyvox (linezolid injection) within 14 days of those drugs can cause very bad high blood pressure.
This is not a list of all drugs or health problems that interact with Zyvox (linezolid injection).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Zyvox (linezolid injection) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Zyvox?
- Tell all of your health care providers that you take Zyvox (linezolid injection). This includes your doctors, nurses, pharmacists, and dentists.
- This medicine may stop your bone marrow from making some of the cells that your body needs. You will be closely watched by your doctor. Tell your doctor right away about any fever, sore throat, signs of infection, bleeding, shortness of breath, or feeling tired.
- Do not use longer than you have been told. A second infection may happen.
- High blood pressure has happened with Zyvox (linezolid injection). Have your blood pressure checked as you have been told by your doctor.
- Talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Very bad eye problems have happened with Zyvox (linezolid injection), mainly in people taking Zyvox (linezolid injection) for longer than 28 days. Some people who took this drug for longer than 28 days had loss of eyesight. Have your eyesight checked as you were told by your doctor. Talk with your doctor.
- If you have high blood sugar (diabetes), talk with your doctor. This medicine may lower blood sugar. High blood sugar drugs may need to be changed.
- Check your blood sugar as you have been told by your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Zyvox (linezolid injection) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Zyvox) best taken?
Use Zyvox (linezolid injection) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Some foods and drinks like cheese and red wine, when taken with Zyvox (linezolid injection), may cause very risky effects such as sudden high blood pressure. To avoid these problems, get a list of foods to avoid.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps.
- Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating.
- A burning, numbness, or tingling feeling that is not normal.
- Change in eyesight.
- Feeling very tired or weak.
- It is common to have diarrhea when taking Zyvox (linezolid injection). Rarely, a very bad form of diarrhea called Clostridium difficile (C diff)–associated diarrhea (CDAD) may occur. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen while you are taking Zyvox (linezolid injection) or within a few months after you stop taking it. Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with your doctor.
- A very bad and sometimes deadly health problem called serotonin syndrome may happen. The risk may be greater if you take Zyvox (linezolid injection) with drugs for depression, migraines, or certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; very bad diarrhea, upset stomach, or throwing up; or very bad headache.
What are some other side effects of Zyvox?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Loose stools (diarrhea).
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Zyvox?
- If you need to store Zyvox (linezolid injection) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Zyvox (linezolid injection), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Zyvox (linezolid)
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