Medically reviewed on April 4, 2018.
Uses of Ziana:
What do I need to tell my doctor BEFORE I take Ziana?
- If you have an allergy to clindamycin, tretinoin, or any other part of Ziana (clindamycin and tretinoin).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are using any products that have erythromycin.
- If you have any of these health problems: History of Crohn's disease, regional enteritis, ulcerative colitis, or very loose stools called antibiotic-associated colitis.
This is not a list of all drugs or health problems that interact with Ziana (clindamycin and tretinoin).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Ziana (clindamycin and tretinoin) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Ziana?
- Tell all of your health care providers that you take Ziana (clindamycin and tretinoin). This includes your doctors, nurses, pharmacists, and dentists.
- Do not put on sunburned skin.
- Do not put on cuts, scrapes, or damaged skin.
- Skin may look worse before it looks better.
- It may take several weeks to see the full effects.
- Use other pimple (acne) drugs with care. More skin irritation may happen.
- Talk with your doctor before you use other drugs or products on your skin.
- Practice good skin care and avoid the sun.
- You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
- Some weather conditions may irritate the skin. Talk with the doctor.
- Diarrhea, bloody diarrhea, and a certain bowel problem (colitis) have happened with Ziana (clindamycin and tretinoin). Very bad colitis may lead to death. Call your doctor right away if you have stomach pain or cramps, very bad or watery diarrhea, or bloody diarrhea. Do not try to treat diarrhea without first checking with your doctor.
- It is common to have skin irritation with Ziana (clindamycin and tretinoin). These reactions may include burning, dry skin, itching, peeling, redness, and scaling. Call your doctor if you have skin irritation that is very bad, bothers you, or does not go away.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Ziana (clindamycin and tretinoin) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Ziana) best taken?
Use Ziana (clindamycin and tretinoin) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Do not take Ziana (clindamycin and tretinoin) by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
- Put on at bedtime.
- Wash your hands before and after use.
- Clean affected part before use. Make sure to dry well.
- Put a thin layer on the affected skin and rub in gently.
- To gain the most benefit, do not miss doses.
What do I do if I miss a dose?
- Put on a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not put on 2 doses or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Very bad irritation where Ziana (clindamycin and tretinoin) is used.
What are some other side effects of Ziana?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Ziana?
- Store at room temperature. Do not freeze.
- Protect from heat.
- Protect from light.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Ziana (clindamycin and tretinoin), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Ziana (clindamycin / tretinoin topical)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 68 Reviews – Add your own review/rating
- Generic Availability
- Drug class: topical acne agents
Other brands: Veltin