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Zazole Cream

Generic Name: terconazole (ter-KON-a-zole)
Brand Name: Terazol

Zazole Cream is used for:

Treating vaginal yeast infections in women. It may also be used for certain conditions as determined by your doctor.

Zazole Cream is an antifungal agent. It works by weakening the fungal cell membrane, thereby killing sensitive fungi that cause yeast infections.

Do NOT use Zazole Cream if:

  • you are allergic to any ingredient in Zazole Cream

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zazole Cream:

Some medical conditions may interact with Zazole Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of liver disease

Some MEDICINES MAY INTERACT with Zazole Cream. However, no specific interactions with Zazole Cream are known at this time.

Ask your health care provider if Zazole Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zazole Cream:

Use Zazole Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Zazole Cream. Talk to your pharmacist if you have questions about this information.
  • Remove the cap from the tube. Reverse the cap and place the puncture tip onto the tube. Push the cap firmly until the tube end is punctured.
  • Screw the applicator onto the tube. Hold the tube with the attached applicator up. Squeeze the tube from the bottom and fill the applicator until the plunger stops. Remove the applicator from the tube.
  • Lie on your back with knees drawn up toward your chest. Hold the filled applicator by the barrel and gently insert it into the vagina as far as it will go comfortably. Slowly press the plunger to release the medicine into the vagina. While keeping the plunger depressed, remove the applicator from the vagina.
  • After each use, pull applicator apart and wash with soap and warm water. An unclean applicator may not function properly. Thoroughly clean the applicator after each use.
  • To clear up your infection completely, use Zazole Cream for the full course of treatment. Keep using it even if you feel better in a few days.
  • If you miss a dose of Zazole Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Zazole Cream.

Important safety information:

  • If your sexual partner has any penile itching, redness, or discomfort, he should consult his health care provider and mention that you are being treated for a yeast infection.
  • You can use Zazole Cream even if you are having your menstrual period. However, you should not use tampons because they may absorb the medicine. Instead, use external pads or napkins until you have finished therapy with Zazole Cream. You may also wish to wear a sanitary napkin if the vaginal medicine leaks.
  • Dry the genital area thoroughly after showering, bathing, or swimming. Change out of a wet bathing suit or damp exercise clothes as soon as possible. A dry environment is less likely to encourage the growth of yeast.
  • Wipe from front to rear (away from the vagina) after a bowel movement.
  • Do not douche unless your doctor specifically tells you to do so. Douching may disturb the vaginal balance.
  • Do not scratch the affected area if you can avoid it. Scratching can cause more irritation and spread the infection.
  • Avoid sexual intercourse while you are using Zazole Cream, unless your doctor tells you otherwise.
  • If your condition does not get better or if it gets worse, check with your doctor.
  • Be sure to use Zazole Cream for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • A very bad skin reaction (toxic epidermal necrolysis) has happened with Zazole Cream. It can cause very bad health problems that may not go away and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
  • Zazole Cream should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zazole Cream while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Zazole Cream.

Possible side effects of Zazole Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Body pain; burning or itching of the vagina; mild headache; painful menstruation; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chills; flu-like symptoms (eg, headache, tiredness, muscle or joint aches, fever, nausea, vomiting); vaginal sensitivity or irritation; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Zazole Cream:

Store Zazole Cream at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zazole Cream out of the reach of children and away from pets.

General information:

  • If you have any questions about Zazole Cream, please talk with your doctor, pharmacist, or other health care provider.
  • Zazole Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Zazole Cream or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Zazole Cream. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Zazole Cream. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Zazole Cream.

Issue Date: June 3, 2015