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Generic Name: bromfenac (BROME-fen-ak)
Brand Name: Examples include Bromday and Xibrom

Xibrom is used for:

Treating eye pain and swelling in patients who have recently had surgery to remove cataracts. It may also be used for other conditions as determined by your doctor.

Xibrom is a nonsteroidal anti-inflammatory drug (NSAID) eye drop. It works by blocking the production of prostaglandin, a substance that causes inflammation (eg, redness, swelling, irritation).

Do NOT use Xibrom if:

  • you are allergic to any ingredient in Xibrom
  • you are in late pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xibrom:

Some medical conditions may interact with Xibrom. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to sulfites, aspirin or any medicine containing aspirin, an NSAID (eg, ibuprofen), or a phenylacetic acid derivative
  • if you have asthma, diabetes, bleeding problems, or rheumatoid arthritis
  • if you have other eye problems (eg, dry eye syndrome, cornea problems), have had complicated eye surgery, or have had repeated eye surgeries within a short period of time

Some MEDICINES MAY INTERACT with Xibrom. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin) or heparin because the risk of bleeding may be increased
  • Corticosteroids (eg, prednisolone) because healing may be slowed or delayed

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xibrom may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xibrom:

Use Xibrom as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • To use Xibrom, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
  • If you will be using Xibrom to treat both eyes after surgery, do not use the same bottle for both eyes. Doing so may increase the risk of passing an infection from one eye to the other.
  • Soft contact lenses may absorb a chemical in Xibrom. Remove contact lenses before you use Xibrom. Ask your doctor how to use your contact lenses while using Xibrom.
  • If you are using another medicine that you put in your eye, use Xibrom at least 5 minutes before or after using the other medicine.
  • If you miss a dose of Xibrom, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Xibrom.

Important safety information:

  • Do not exceed the recommended dose or use Xibrom for longer than prescribed without checking with your doctor.
  • If your symptoms do not improve within 14 days or if they become worse, check with your doctor.
  • Check with your doctor if you have an eye wound or irritation that does not heal.
  • Xibrom contains sulfites, which can cause allergic reactions in certain individuals. Asthma patients may be at higher risk of these allergic reactions. If you have previously had allergic reactions to sulfites, contact your doctor or pharmacist before using Xibrom.
  • Xibrom should be used with caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Xibrom may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Xibrom while you are pregnant. Avoid use of Xibrom during late pregnancy. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use Xibrom, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Xibrom:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Eye burning, irritation, itching, pain, redness, stinging, or swelling; headache; unusual feeling in the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe eye burning, irritation, itching, redness, stinging, or swelling; unusual bleeding of the eye; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Xibrom:

Store Xibrom between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Xibrom out of the reach of children and away from pets.

General information:

  • If you have any questions about Xibrom, please talk with your doctor, pharmacist, or other health care provider.
  • Xibrom is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Xibrom or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Xibrom. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Xibrom. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Xibrom.

Issue Date: June 3, 2015

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.