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Generic Name: IncobotulinumtoxinA (in kuh BOT yoo lin num TOKS in aye)
Brand Name: Xeomin

Medically reviewed by Last updated on Aug 23, 2020.


  • Very bad side effects have happened when Xeomin (incobotulinumtoxinA) has spread from where it is being used. These signs can happen within hours up to weeks after the shot. Swallowing and breathing problems can cause death. The risk is greatest in children with current muscle problems. Call your doctor right away if you have blurred eyesight, change in voice, drooping eyelids, or loss of strength or weakness all over the body. Call your doctor right away if you are not able to control your bladder, are seeing double, or have trouble breathing, speaking, or swallowing.

Uses of Xeomin:

  • It is used to treat muscle problems that lead to spasms.
  • It is used to treat muscle problems around the eye.
  • It is used to treat spasms of the neck.
  • It is used to lower the number of lines and wrinkles of the face.
  • It is used to reduce drooling.

What do I need to tell my doctor BEFORE I take Xeomin?

  • If you have an allergy to incobotulinumtoxinA, albumin, or any other part of Xeomin (incobotulinumtoxinA).
  • If you are allergic to Xeomin (incobotulinumtoxinA); any part of Xeomin (incobotulinumtoxinA); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have an infection where the shot will be given.

This is not a list of all drugs or health problems that interact with Xeomin (incobotulinumtoxinA).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Xeomin (incobotulinumtoxinA) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Xeomin?

  • Tell all of your health care providers that you take Xeomin (incobotulinumtoxinA). This includes your doctors, nurses, pharmacists, and dentists.
  • Talk with your doctor if you have had a botulinum toxin product in the last 3 or 4 months.
  • Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how Xeomin (incobotulinumtoxinA) affects you.
  • This medicine is made from human plasma (part of the blood) and may have viruses that may cause disease. This medicine is screened, tested, and treated to lower the chance that it carries an infection. Talk with the doctor.
  • If you are 65 or older, use Xeomin (incobotulinumtoxinA) with care. You could have more side effects.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Xeomin) best taken?

Use Xeomin (incobotulinumtoxinA) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot.

What do I do if I miss a dose?

  • Call the doctor for an office visit.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
  • Eye pain.
  • Eye irritation.
  • Dizziness or passing out.
  • Seizures.

What are some other side effects of Xeomin?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Pain where the shot was given.
  • Headache.
  • Neck pain.
  • Dry mouth.
  • Less blinking.
  • Dry eyes.
  • Feeling tired or weak.
  • Diarrhea.
  • Tooth pain.
  • Muscle pain.
  • Bone pain.
  • Nose or throat irritation.
  • Signs of a common cold.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Xeomin?

  • If you need to store Xeomin (incobotulinumtoxinA) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Xeomin (incobotulinumtoxinA) is refilled. If you have any questions about Xeomin (incobotulinumtoxinA), please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Frequently Asked Questions