Generic Name: Vincristine (vin KRIS teen)
Brand Name: Vincasar PFS
Medically reviewed by Drugs.com. Last updated on Apr 29, 2019.
- This medicine is given as a shot into a vein only. If given other ways, this can be deadly. Talk with the doctor.
- This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
Uses of Vincristine:
- It is used to treat cancer.
What do I need to tell my doctor BEFORE I take Vincristine?
- If you have an allergy to vincristine or any other part of vincristine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have Charcot-Marie-Tooth syndrome.
- If you are breast-feeding or plan to breast-feed.
This is not a list of all drugs or health problems that interact with vincristine.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take vincristine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Vincristine?
- Tell all of your health care providers that you take vincristine. This includes your doctors, nurses, pharmacists, and dentists.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- Some side effects may happen up to 2 weeks after the shot. Report them to the doctor.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- If you have upset stomach, throwing up, diarrhea, or are not hungry, talk with your doctor. There may be ways to lower these side effects.
- If you have constipation, talk with your doctor. There may be ways to lower this side effect.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Talk with your doctor before getting any vaccines. Use of some vaccines with vincristine may either raise the chance of an infection or make the vaccine not work as well.
- Use with care in children. Talk with the doctor.
- This medicine may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child. In both men and women, this may go back to normal but sometimes it may not. Talk with your doctor.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- Use birth control that you can trust to prevent pregnancy while taking vincristine.
- If you are pregnant or you get pregnant while taking vincristine, call your doctor right away.
How is this medicine (Vincristine) best taken?
Use vincristine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a vein.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Shortness of breath.
- A burning, numbness, or tingling feeling that is not normal.
- Muscle weakness.
- Trouble walking.
- Change in balance.
- Very bad constipation.
- Very bad belly pain.
- Feeling very tired or weak.
- Change in eyesight.
- Loss of eyesight.
- Not able to control eye movements.
- Change in hearing.
- Hearing loss. This can be long-lasting.
- Any unexplained bruising or bleeding.
- Very bad headache.
- Dizziness or passing out.
- Passing urine more often.
- Pain when passing urine.
- Throat, neck, or jaw pain.
- Very bad and sometimes deadly liver problems have happened with vincristine. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
What are some other side effects of Vincristine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Stomach cramps.
- Weight loss.
- Feeling tired or weak.
- Hair loss.
- Upset stomach or throwing up.
- Not hungry.
- Bone, joint, or muscle pain.
- Back pain.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Vincristine?
- If you need to store vincristine at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about vincristine, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about vincristine
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
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- Drug class: mitotic inhibitors