Generic Name: Elosulfase Alfa (el oh SUL fase AL fa)
Brand Name: Vimizim
Medically reviewed on April 4, 2018.
- Very bad and sometimes deadly allergic side effects have happened during infusion of Vimizim (elosulfase alfa). You will be watched closely during and after the infusion. Tell your doctor right away if you have a cough, skin redness, tightness in the throat, itching, flushing, blue skin, very bad dizziness or passing out, rash, shortness of breath, chest pain, upset stomach or throwing up, or stomach pain during the infusion.
- If you have lung or breathing problems, the chance of them getting worse may be raised. The chance may also be raised if you have a fever. These effects may be life-threatening. Talk with your doctor.
Uses of Vimizim:
- It is used to treat mucopolysaccharidosis type IVA (MPS IVA or Morquio A syndrome).
What do I need to tell my doctor BEFORE I take Vimizim?
- If you have an allergy to elosulfase alfa or any other part of Vimizim (elosulfase alfa).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Vimizim (elosulfase alfa) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Vimizim?
- Tell all of your health care providers that you take Vimizim (elosulfase alfa). This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how Vimizim (elosulfase alfa) affects you.
- Other drugs may be given to help with infusion side effects.
- You may need to use birth control to prevent pregnancy while taking Vimizim (elosulfase alfa). Talk with your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Vimizim (elosulfase alfa) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Vimizim) best taken?
Use Vimizim (elosulfase alfa) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Swelling in the arms or legs.
- Neck pain.
- Back pain.
- Weakness, numbness, or tingling.
- Not able to move.
- Not able to control stools or urine.
- Fever or chills.
What are some other side effects of Vimizim?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Vimizim?
- If you need to store Vimizim (elosulfase alfa) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Vimizim (elosulfase alfa), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
- This information should not be used to decide whether or not to take Vimizim (elosulfase alfa) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Vimizim (elosulfase alfa). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Vimizim (elosulfase alfa). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using Vimizim (elosulfase alfa).
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Vimizim (elosulfase alfa)
- Side Effects
- During Pregnancy
- Dosage Information
- Support Group
- Pricing & Coupons
- En Español
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- Drug class: lysosomal enzymes