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Generic Name: phenazopyridine/butabarbital/hyoscyamine (fen-AY-zoe-PIR-i-deen/BUE-ta-BAR-bi-tal/HYE-oh-SYE-a-meen)
Brand Name: Examples include PhenazoForte Plus and Urelief Plus
Urelief Plus is used for:
Relieving pain, burning, urgency, frequent urination, and discomfort caused by irritation of the lower urinary tract. It may also be used for other conditions as determined by your doctor.
Urelief Plus is an analgesic, anticholinergic, and antianxiety combination. It works by decreasing the motion of muscles in the stomach, intestines, and bladder. It also decreases the production of stomach acid.
Do NOT use Urelief Plus if:
- you are allergic to any ingredient in Urelief Plus
- you have the blood disease porphyria; decreased liver or kidney function; severe esophagus problems (eg, irritation, narrowing); a blockage of the stomach, bowel, or bladder; bowel motility problems; or severe bowel problems (eg, severe ulcerative colitis, toxic megacolon)
- you have glaucoma, myasthenia gravis, or heart problems caused by severe bleeding
- you are taking sodium oxybate (GHB)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Urelief Plus:
Some medical conditions may interact with Urelief Plus. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have nerve problems, prostate problems, esophagus problems (eg, reflux), stomach or bowel problems, heart or blood vessel problems (eg, fast or irregular heartbeat, heart failure, coronary heart disease), lung or breathing problems, hiatal hernia, kidney or liver problems, an overactive thyroid, high blood pressure, urinary problems, paralysis, or brain damage, or if you are at risk for glaucoma
- if you have diarrhea or fever, have been very ill, or are in poor health
- if you have an enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency, a family history of this deficiency, or a history of certain blood problems (eg, hemolysis)
- if you have a history of substance abuse or dependence, mental or mood problems (eg, depression), or suicidal thoughts or behavior
Some MEDICINES MAY INTERACT with Urelief Plus. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Amantadine, antihistamines (eg, diphenhydramine), haloperidol, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), other anticholinergics (eg, scopolamine), phenothiazines (eg, thioridazine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Urelief Plus's side effects
- Narcotic pain medicines (eg, codeine) or potassium chloride because the risk of their side effects may be increased by Urelief Plus
- Beta-blockers (eg, atenolol), clozapine, corticosteroids (eg, prednisone), doxycycline, estrogens (eg, micronized estradiol), griseofulvin, ketoconazole, metronidazole, oral contraceptives (birth control pills), phenytoin, quinidine, theophylline, or valproic acid because their effectiveness may be decreased by Urelief Plus
This may not be a complete list of all interactions that may occur. Ask your health care provider if Urelief Plus may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Urelief Plus:
Use Urelief Plus as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Urelief Plus by mouth after meals.
- Taking Urelief Plus at the same time(s) each day will help you remember to take it.
- If you miss a dose of Urelief Plus, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Urelief Plus.
Important safety information:
- Urelief Plus may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Urelief Plus with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Urelief Plus; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Do NOT take more than the recommended dose or use for longer than 2 days without checking with your doctor.
- Urelief Plus may change the color of your urine to orange or red. It may also stain fabric. This is normal and not a cause for concern.
- Do not wear soft contact lenses while taking Urelief Plus; permanent staining of the lenses may occur.
- Do not become overheated or dehydrated in hot weather or while you are being active; heatstroke may occur.
- Urelief Plus may cause dry mouth. To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.
- Hormonal birth control (eg, birth control pills) may not work as well while you are using Urelief Plus. To prevent pregnancy, use an extra form of birth control (eg, condoms).
- Urelief Plus may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
- Tell your doctor or dentist that you take Urelief Plus before you receive any medical or dental care, emergency care, or surgery.
- Do not use Urelief Plus for future urinary tract problems without first checking with your doctor.
- Urelief Plus may interfere with certain lab tests, including urinalysis. Be sure your doctor and lab personnel know you are taking Urelief Plus.
- Use Urelief Plus with caution in the ELDERLY; they may be more sensitive to its effects, agitation, confusion, drowsiness, dry mouth, especially constipation, excitability, memory problems, or trouble urinating.
- PREGNANCY AND BREAST-FEEDING: It is not known if Urelief Plus can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Urelief Plus while you are pregnant. Urelief Plus is found in breast milk. If you are or will be breast-feeding while taking Urelief Plus, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Urelief Plus:
All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Bloated feeling; blurred vision; clumsiness; constipation; decreased sweating; dizziness; drowsiness; dry mouth; enlarged pupils; excessive daytime drowsiness; excitability; headache; lightheadedness; nausea; trouble sleeping; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; blue or purple skin color; confusion; decreased urination; disorientation; fainting; fast or irregular heartbeat; hallucinations; loss of consciousness; loss of coordination; mental or mood changes (eg, agitation, unusual behavior changes); shortness of breath; unusual tiredness or weakness; vision changes (eg, trouble focusing eyes); yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blue or purple skin color; disorientation; excessive thirst or excitability; fever; hot, dry skin; seizures; severe dry mouth; severe or persistent blurred vision, dizziness, headache, nausea, or vomiting; trouble breathing or swallowing; unusual fatigue.Proper storage of Urelief Plus:
Store Urelief Plus at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Urelief Plus out of the reach of children and away from pets.
- If you have any questions about Urelief Plus, please talk with your doctor, pharmacist, or other health care provider.
- Urelief Plus is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Urelief Plus or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Urelief Plus. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Urelief Plus. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Urelief Plus.