Treprostinil Extended-Release Tablets
Generic name: Treprostinil Extended-Release Tablets (tre PROST in il)
Brand name: Orenitram
Drug class: Agents for pulmonary hypertension
Medically reviewed by Drugs.com. Last updated on Oct 14, 2020.
Uses of Treprostinil Extended-Release Tablets:
- It is used to treat high blood pressure in the lungs.
What do I need to tell my doctor BEFORE I take Treprostinil Extended-Release Tablets?
- If you are allergic to this medicine (treprostinil extended-release tablets); any part of this medicine (treprostinil extended-release tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have liver disease.
This is not a list of all drugs or health problems that interact with this medicine (treprostinil extended-release tablets).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (treprostinil extended-release tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Treprostinil Extended-Release Tablets?
- Tell all of your health care providers that you take this medicine (treprostinil extended-release tablets). This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (treprostinil extended-release tablets) affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Do not stop taking this medicine (treprostinil extended-release tablets) all of a sudden without calling your doctor. Signs of high pressure in the lungs like shortness of breath, dizziness, or weakness may get worse. Talk with your doctor.
- The tablet shell does not dissolve. If you have a certain bowel problem (diverticulosis), this may be a problem. Talk with your doctor.
- If you are 65 or older, use this medicine (treprostinil extended-release tablets) with care. You could have more side effects.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Treprostinil Extended-Release Tablets) best taken?
Use this medicine (treprostinil extended-release tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take this medicine (treprostinil extended-release tablets) with food.
- Do not swallow whole. Do not chew, break, or crush.
- Do not take chipped or broken tablets.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it, with food.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you miss 2 doses, call your doctor.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of bleeding like throwing up or coughing up blood; vomit that looks like coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a cause or that get bigger; or bleeding you cannot stop.
- Very bad dizziness or passing out.
- Shortness of breath, a big weight gain, or swelling in the arms or legs.
- Trouble breathing that is new or worse.
- Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal.
What are some other side effects of Treprostinil Extended-Release Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Dizziness or headache.
- Jaw pain.
- Upset stomach or throwing up.
- Pain in arms or legs.
- Stomach pain.
- You may see the tablet shell in your stool. This is normal and not a cause for concern.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Treprostinil Extended-Release Tablets?
- Store at room temperature in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (treprostinil extended-release tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.
More about treprostinil
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- 16 Reviews
- Drug class: agents for pulmonary hypertension
- Drug Information
- Treprostinil inhalation
- Treprostinil injection
- Treprostinil (Advanced Reading)
- Treprostinil Inhalation (Advanced Reading)
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.