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Tetrahydrozoline solution

Generic Name: tetrahydrozoline (teh-trah-high-DRAHZ-ah-leen)
Brand Name: Tyzine

Tetrahydrozoline solution is used for:

Treating nasal congestion due to colds, hay fever, allergies, or sinusitis. It may also be used to treat other conditions as determined by your doctor.

Tetrahydrozoline solution is a decongestant. It works by shrinking swollen and congested nasal tissues by constricting blood vessels. This improves drainage of mucus and breathing through the nose.

Do NOT use tetrahydrozoline solution if:

  • you are allergic to any ingredient in tetrahydrozoline solution
  • you are currently taking furazolidone or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using tetrahydrozoline solution:

Some medical conditions may interact with tetrahydrozoline solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have high blood pressure, heart disease, an overactive thyroid, or diabetes

Some MEDICINES MAY INTERACT with tetrahydrozoline solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Tricyclic antidepressants (eg, amitriptyline) because the effectiveness of tetrahydrozoline solution may be decreased
  • Furazolidone and MAO inhibitors (eg, phenelzine) because side effects such as headache, high blood pressure, and elevated body temperature may occur
  • Bromocriptine or catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone, St. John's wort) because the actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if tetrahydrozoline solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use tetrahydrozoline solution:

Use tetrahydrozoline solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Gently blow your nose before using tetrahydrozoline solution.
  • To use nose drops: Lie down and tilt your head back. Breathe through your mouth. Insert the dropper tip in the nose no more than 1 3 inch. Try not to touch the dropper tip to the inside of your nose. Place the correct number of drops in your nose. Continue to lie down with your head tilted back for 2 minutes.
  • To use nose spray: Sit down and tilt your head back slightly. Place the tip of the spray container into the nose. Using a finger from your other hand, press against the opposite nostril to close it off. Breathe gently through the open nostril and squeeze the spray container. If you are using more than 1 spray, wait for 1 to 2 minutes between sprays. After using the medicine, rinse the tip of the spray unit in hot water and dry with a clean tissue to prevent contamination.
  • If you miss a dose of tetrahydrozoline solution and you are using it regularly, use it as soon as possible. If it is much more than 1 hour since your missed dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use tetrahydrozoline solution.

Important safety information:

  • Tetrahydrozoline solution may cause drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to tetrahydrozoline solution. Using tetrahydrozoline solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Tetrahydrozoline solution is for nasal use only. Avoid contact with the eyes and mouth. Illness may occur if tetrahydrozoline solution is taken by mouth.
  • Use tetrahydrozoline solution at bedtime to avoid sleep interruption and sleeplessness.
  • Diabetes patients - Tetrahydrozoline solution may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
  • Tetrahydrozoline solution is not recommended for use in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using tetrahydrozoline solution during pregnancy. It is unknown if tetrahydrozoline solution is excreted in breast milk. If you are or will be breast-feeding while you are using tetrahydrozoline solution, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of tetrahydrozoline solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning; dry mouth, nose, or throat; increase in nasal discharge; sneezing; stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); excessive sweating; pale skin color; pounding in the chest; severe drowsiness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include changes in heartbeat; drowsiness; fainting; pale skin color.

Proper storage of tetrahydrozoline solution:

Store tetrahydrozoline solution below 86 degrees F (30 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep tetrahydrozoline solution out of the reach of children and away from pets.

General information:

  • If you have any questions about tetrahydrozoline solution, please talk with your doctor, pharmacist, or other health care provider.
  • Tetrahydrozoline solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take tetrahydrozoline solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about tetrahydrozoline solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to tetrahydrozoline solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using tetrahydrozoline solution.

Review Date: August 8, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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