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Tbo-Filgrastim Injection

Generic Name: Tbo-Filgrastim Injection (t b o fil GRA stim)
Brand Name: Granix

Uses of Tbo-Filgrastim Injection:

  • It is used to lower the chance of getting an infection in people with bone marrow problems caused by chemo.
  • It is used to raise the number of white blood cells in certain patients.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Tbo-Filgrastim Injection?

  • If you have an allergy to filgrastim or any other part of tbo-filgrastim injection.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Tbo-Filgrastim Injection?

  • Tell all of your health care providers that you take tbo-filgrastim injection. This includes your doctors, nurses, pharmacists, and dentists.
  • Do not get this medicine at the same time or within 24 hours before or after chemo or radiation treatment. Talk with your doctor.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take tbo-filgrastim injection.
  • This medicine may cause a very bad and sometimes deadly problem called capillary leak syndrome (CLS). CLS may lead to low blood pressure and harm to the body. It may also lead to a heartbeat that is not normal, chest pain or pressure, heart attack, lung or breathing problems, bleeding or lower blood flow in the stomach or bowel, kidney problems, swelling, or feeling confused. Talk with the doctor.
  • Some people with sickle cell disease have had times where the sickle cell disease has gotten worse when taking this medicine. Sometimes, this has been deadly. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using tbo-filgrastim injection while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Tbo-Filgrastim Injection) best taken?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot into the fatty part of the skin.
  • To gain the most benefit, do not miss doses.
  • Keep taking tbo-filgrastim injection as you have been told by your doctor or other health care provider, even if you feel well.
  • If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
  • Follow how to use as you have been told by the doctor or read the package insert.
  • Before using this medicine, take it out of the refrigerator and leave it at room temperature for 30 minutes.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.
  • Do not shake the solution.
  • Wash your hands before and after you give the shot.
  • Do not give into skin that is irritated, bruised, red, infected, or scarred.
  • Move the site where you give the shot with each shot.
  • Throw away any part left over after the dose is given.
  • Throw syringe away after use. Do not use the same syringe more than one time.
  • Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
  • Do not switch between different brands of tbo-filgrastim injection without first talking with the doctor.
  • If you get this medicine on the skin, wash it off right away with soap and water.
  • If you get tbo-filgrastim injection in the eyes, flush right away with cool water and get medical help.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

Dosage Information (comprehensive)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • Dark urine.
  • A fast heartbeat.
  • Dizziness or passing out.
  • Sweating a lot.
  • Shortness of breath.
  • Fast breathing.
  • Fever.
  • Coughing up blood.
  • Feeling very tired or weak.
  • Any unexplained bruising or bleeding.
  • Purple spots or redness of the skin.
  • Very bad headache.
  • Swelling.
  • Enlarged and ruptured spleens have happened with this medicine. Sometimes, ruptured spleens have been deadly. Call your doctor right away if you have left upper stomach pain or left shoulder pain.

What are some other side effects of Tbo-Filgrastim Injection?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Back pain.
  • Bone pain.
  • Joint pain.
  • Cough.
  • Headache.
  • Upset stomach.
  • Feeling tired or weak.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Side Effects (complete list)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Tbo-Filgrastim Injection?

  • Store in a refrigerator. Do not freeze.
  • Store in original container.
  • Protect from light.
  • If needed, tbo-filgrastim injection can be left out at room temperature for up to 5 days. If not used within 5 days of being left out at room temperature, you can return this medicine to the refrigerator. Do not do this more than 1 time.
  • Throw away unopened drug if left at room temperature for more than 5 days.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about tbo-filgrastim injection, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about tbo-filgrastim injection. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using tbo-filgrastim injection.

Review Date: November 1, 2017

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