Generic Name: silodosin (sye-LOE-doe-sin)
Brand Name: Rapaflo
Silodosin is used for:
Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).
Silodosin is an alpha-blocker. It works by relaxing muscles in the prostate and bladder, which helps to improve urine flow and reduce symptoms of BPH.
Do NOT use silodosin if:
- you are allergic to any ingredient in silodosin
- you have severe kidney or liver problems
- you are taking ketoconazole, boceprevir, clarithromycin, cobicistat, cyclosporine, itraconazole, nefazodone, posaconazole, ritonavir, telaprevir, or telithromycin
- you are taking another alpha-blocker (eg, prazosin)
Contact your doctor or health care provider right away if any of these apply to you.
Before using silodosin:
Some medical conditions may interact with silodosin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of blood pressure problems
- if you have a history of prostate cancer
- if you have kidney or liver problems
- if you will be having eye surgery (eg, cataract surgery)
Some MEDICINES MAY INTERACT with silodosin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Alpha-blockers (eg, prazosin), phosphodiesterase inhibitors (eg, sildenafil), or medicines for high blood pressure because symptoms of low blood pressure (eg, severe dizziness, light-headedness, fainting) may occur
- Azole antifungals (eg, fluconazole, itraconazole, ketoconazole), clarithromycin, cobicistat, cyclosporine, diltiazem, erythromycin, nefazodone, probenecid, protease inhibitors (eg, boceprevir, ritonavir), telithromycin, valproic acid, or verapamil because they may increase the risk of silodosin's side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if silodosin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use silodosin:
Use silodosin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take silodosin by mouth with a meal.
- Swallow silodosin whole. Do not break, crush, or chew before swallowing. If you cannot swallow the capsule whole, you may open it and sprinkle the contents over a spoonful of applesauce. Mix the medicine with the applesauce and swallow the mixture right away, followed by a glass of water. Do not crush or chew the medicine before swallowing. Do not store the mixture for future use.
- If you miss a dose of silodosin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use silodosin.
Important safety information:
- Silodosin may cause dizziness, light-headedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use silodosin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Silodosin may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Tell your doctor or dentist that you take silodosin before you receive any medical or dental care, emergency care, or surgery.
- Silodosin may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
- Lab tests, including kidney or liver function, may be performed while you use silodosin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Silodosin should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: It is not known if silodosin can cause harm to the fetus. It is not known if this medicine is found in breast milk. Silodosin is not approved for use in women.
Possible side effects of silodosin:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Decreased sexual ability; dizziness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine; fainting; prolonged, painful erection; severe or persistent dizziness; unusual bruising; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fainting; severe or persistent dizziness or light-headedness.Proper storage of silodosin:
Store silodosin at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep silodosin out of the reach of children and away from pets.
- If you have any questions about silodosin, please talk with your doctor, pharmacist, or other health care provider.
- Silodosin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take silodosin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about silodosin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to silodosin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using silodosin.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about silodosin
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 96 Reviews – Add your own review/rating
- Drug class: antiadrenergic agents, peripherally acting
Other brands: Rapaflo