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Rebetol (Oral Solution)

Generic Name: Ribavirin Oral Solution (rye ba VYE rin)
Brand Name: Rebetol

Medically reviewed by Drugs.com. Last updated on Apr 18, 2019.

Warning

  • Do not take Rebetol (ribavirin oral solution) alone to treat hepatitis C infection.
  • A severe blood problem called hemolytic anemia has happened with Rebetol (ribavirin oral solution). This can make heart disease worse and lead to heart attacks, which can be deadly. Tell your doctor if you have ever had heart problems. Get medical help right away if you have chest pain while taking Rebetol (ribavirin oral solution).
  • Do not take if you are pregnant. Use during pregnancy may cause birth defects or loss of the unborn baby. If you get pregnant or plan on getting pregnant while taking Rebetol (ribavirin oral solution), call your doctor right away.
  • Use 2 kinds of birth control that you can trust while using Rebetol (ribavirin oral solution) and for 6 months after stopping Rebetol (ribavirin oral solution).
  • Do not take Rebetol (ribavirin oral solution) if you are a man with a sex partner who is pregnant.
  • If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during treatment and for 6 months after your last dose. Use 2 kinds of birth control.
  • If you or your sex partner gets pregnant while taking Rebetol (ribavirin oral solution) or within 6 months after stopping Rebetol (ribavirin oral solution), call your doctor right away.

Uses of Rebetol:

  • It is used to treat hepatitis C infection.
  • This medicine may be used along with interferon or peginterferon. If you are using one of these drugs, read the patient fact sheet that comes with it.

What do I need to tell my doctor BEFORE I take Rebetol?

  • If you have an allergy to ribavirin or any other part of Rebetol (ribavirin oral solution).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Autoimmune hepatitis, liver problems other than hepatitis C, kidney disease, sickle cell anemia, or thalassemia major.
  • If you are taking didanosine.
  • If you are of childbearing age, but are not using 2 kinds of birth control or if you are planning to get pregnant during your treatment or within 6 months after your last dose.

This is not a list of all drugs or health problems that interact with Rebetol (ribavirin oral solution).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Rebetol (ribavirin oral solution) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Rebetol?

  • Tell all of your health care providers that you take Rebetol (ribavirin oral solution). This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • You may need to have an ECG checked before starting Rebetol (ribavirin oral solution) and while taking it. Talk with your doctor.
  • Have your lung function checked as you have been told by your doctor. Talk with your doctor.
  • This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors.
  • Watch for gout attacks.
  • Avoid drinking alcohol. Alcohol may make liver disease worse.
  • Take good care of your teeth. See a dentist often.
  • If you throw up, rinse your mouth out well.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
  • This medicine may affect growth in children and teens in some cases. They may need regular growth checks. Talk with the doctor.
  • If giving Rebetol (ribavirin oral solution) to your child and your child's weight changes, talk with the doctor. The dose of Rebetol (ribavirin oral solution) may need to be changed.
  • This medicine may affect being able to father a child. Talk with the doctor.
  • If you are a woman of childbearing age, take a pregnancy test each month while you take Rebetol (ribavirin oral solution) and for 6 months after care ends.
  • If you are a man with a female sex partner who may get pregnant, she will need a pregnancy test each month during your treatment and for 6 months after your last dose.
  • If you have sex without using 2 kinds of birth control that you can trust, if you think you may be pregnant, or if you miss your period, call your doctor right away.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Rebetol) best taken?

Use Rebetol (ribavirin oral solution) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with food.
  • Measure liquid doses carefully. Use the measuring device that comes with Rebetol (ribavirin oral solution). If there is none, ask the pharmacist for a device to measure Rebetol (ribavirin oral solution).
  • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
  • Keep taking Rebetol (ribavirin oral solution) as you have been told by your doctor or other health care provider, even if you feel well.
  • It is important that you do not miss or skip a dose of Rebetol (ribavirin oral solution) during treatment.
  • Do not take Rebetol (ribavirin oral solution) for longer than you were told by your doctor.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • If you are not sure what to do if you miss a dose, call your doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
  • Change in eyesight.
  • Loss of eyesight.
  • Pale skin.
  • Feeling confused.
  • Not able to focus.
  • Period (menstrual) changes.
  • Drugs like this one have raised the chance of suicidal thoughts or actions in children and young adults. The risk may be greater in people who have had these thoughts or actions in the past. All people who take Rebetol (ribavirin oral solution) need to be watched closely. Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur.
  • Low blood cell counts have happened with Rebetol (ribavirin oral solution). If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Call your doctor right away if you have signs of infection like fever, chills, or sore throat; any unexplained bruising or bleeding; or if you feel very tired or weak.
  • Some people have had lung problems with Rebetol (ribavirin oral solution). Sometimes, this has been deadly. Call your doctor right away if you have signs of lung problems like shortness of breath or other trouble breathing, cough that is new or worse, or fever.

What are some other side effects of Rebetol?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Rebetol?

  • Store liquid (solution) at room temperature or in a refrigerator. Do not freeze.
  • Store in a dry place. Do not store in a bathroom.
  • Keep lid tightly closed.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Rebetol (ribavirin oral solution) is refilled. If you have any questions about Rebetol (ribavirin oral solution), please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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