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Pseudoephedrine/ methscopolamine sustained-release tablets

Generic Name: pseudoephedrine/methscopolamine (SOO-doe-e-FED-rin/METH-skoe-POL-a-meen with KLOR-fen-IR-a-meen/METH-skoe-POL-a-meen)
Brand Name: VisRx

Pseudoephedrine/ methscopolamine sustained-release tablets are used for:

Relieving congestion, sneezing, runny nose, and itchy, watery eyes caused by allergies or the common cold. It may also be used for other conditions as determined by your doctor.

Pseudoephedrine/methscopolamine sustained-release tablets are a combination pack containing a morning dose and an evening dose. The morning dose has a decongestant and an anticholinergic medicine. The evening dose has an antihistamine and an anticholinergic medicine. The decongestant works by shrinking swollen tissue in the nose. The antihistamine works by blocking histamine, a substance in the body that causes sneezing, runny nose, and watery eyes. The anticholinergic works by drying mucous membranes in the nose and chest.

Do NOT use pseudoephedrine/ methscopolamine sustained-release tablets if:

  • you are allergic to any ingredient in pseudoephedrine/methscopolamine sustained-release tablets
  • you are breast-feeding
  • you are taking droxidopa, furazolidone, a phosphodiesterase inhibitor (eg, sildenafil), sodium oxybate (GHB), or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), or if you have taken an MAOI within the past 14 days
  • you have severe heart blood vessel problems, severe high blood pressure, narrow-angle glaucoma, difficulty urinating, or peptic ulcer
  • you are having an asthma attack

Contact your doctor or health care provider right away if any of these apply to you.

Before using pseudoephedrine/ methscopolamine sustained-release tablets:

Some medical conditions may interact with pseudoephedrine/methscopolamine sustained-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are taking or have taken medicine for high blood pressure or depression in the last 14 days
  • if you have a bladder blockage, an enlarged prostate, or trouble urinating
  • if you have blood vessel problems (eg, hardening of the arteries), diabetes, glaucoma, heart problems (eg, irregular heartbeat, heart failure), high blood pressure, kidney problems, liver problems, lung or breathing problems (eg asthma, sleep apnea), a hiatal hernia, an adrenal gland tumor (pheochromocytoma), myasthenia gravis (muscle weakness), nerve problems (eg, neuropathy), stomach or bowel problems (eg, constipation, ulcerative colitis, motility problems, blockage), trouble sleeping, or an overactive thyroid
  • if you have a history of alcohol abuse
  • if you take potassium chloride tablets or capsules

Some MEDICINES MAY INTERACT with pseudoephedrine/methscopolamine sustained-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Droxidopa or sodium oxybate (GHB) because the risk of severe drowsiness, breathing problems, seizures, irregular heartbeat, or heart attack may be increased
  • Alkalinizers (eg, sodium bicarbonate), anticholinergics (eg, benztropine, dicyclomine), antipsychotics (eg, chlorpromazine), beta-blockers (eg, propranolol), carbonic anhydrase inhibitors (eg, acetazolamide), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, MAOIs (eg, phenelzine), phosphodiesterase inhibitors (eg, sildenafil), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of pseudoephedrine/methscopolamine sustained-release tablets's side effects
  • Bromocriptine or digoxin because the risk of their side effects may be increased by pseudoephedrine/methscopolamine sustained-release tablets
  • Guanadrel, guanethidine, mecamylamine, methyldopa, reserpine, or other medicines for high blood pressure because their effectiveness may be decreased by pseudoephedrine/methscopolamine sustained-release tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if pseudoephedrine/methscopolamine sustained-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use pseudoephedrine/ methscopolamine sustained-release tablets:

Use pseudoephedrine/methscopolamine sustained-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take pseudoephedrine/methscopolamine sustained-release tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Swallow pseudoephedrine/methscopolamine sustained-release tablets whole. Do not break, crush, or chew before swallowing.
  • This product contains 2 different tablets: one for the morning and one for the evening. Be sure you understand how to take pseudoephedrine/methscopolamine sustained-release tablets. Check with your doctor or pharmacist if you are not sure which tablet to take in the morning or in the evening.
  • Do not take pseudoephedrine/methscopolamine sustained-release tablets at the same time as antacids, certain medicines for diarrhea (eg, kaolin, pectin, attapulgite, bismuth), or ketoconazole. Take these medicines 2 or 3 hours before or after taking pseudoephedrine/methscopolamine sustained-release tablets.
  • If you miss a dose of pseudoephedrine/methscopolamine sustained-release tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use pseudoephedrine/methscopolamine sustained-release tablets.

Important safety information:

  • Pseudoephedrine/methscopolamine sustained-release tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use pseudoephedrine/methscopolamine sustained-release tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using pseudoephedrine/methscopolamine sustained-release tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Pseudoephedrine/methscopolamine sustained-release tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking pseudoephedrine/methscopolamine sustained-release tablets.
  • Pseudoephedrine/methscopolamine sustained-release tablets may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking pseudoephedrine/methscopolamine sustained-release tablets for a few days before the tests.
  • Pseudoephedrine/methscopolamine sustained-release tablets may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
  • Pseudoephedrine/methscopolamine sustained-release tablets may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
  • Pseudoephedrine/methscopolamine sustained-release tablets may reduce sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • Pseudoephedrine/methscopolamine sustained-release tablets contains the stimulant pseudoephedrine. Do not take diet or appetite control medicines while you are taking pseudoephedrine/methscopolamine sustained-release tablets without checking with your doctor.
  • Pseudoephedrine/methscopolamine sustained-release tablets has a decongestant and an antihistamine in it. Before you start any new medicine, check the label to see if it has a decongestant or an antihistamine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Diabetes patients - Pseudoephedrine/methscopolamine sustained-release tablets may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Use pseudoephedrine/methscopolamine sustained-release tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Pseudoephedrine/methscopolamine sustained-release tablets should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if pseudoephedrine/methscopolamine sustained-release tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using pseudoephedrine/methscopolamine sustained-release tablets while you are pregnant. Pseudoephedrine/methscopolamine sustained-release tablets are found in breast milk. Do not breast-feed while taking pseudoephedrine/methscopolamine sustained-release tablets.

When used for long periods of time, pseudoephedrine/methscopolamine sustained-release tablets may not work as well. This is known as TOLERANCE. Increasing the dose may cause toxic side effects to occur.

If you suddenly stop taking pseudoephedrine/methscopolamine sustained-release tablets, WITHDRAWAL symptoms, including worsening of congestion, may occur.

Possible side effects of pseudoephedrine/ methscopolamine sustained-release tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; dizziness; drowsiness; dry mouth, nose, or throat; excitability or irritability (especially in children); headache; lack of energy; lightheadedness; nausea; nervousness; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast or irregular heartbeat; flushing; hallucinations; mental or mood changes (eg, anxiety); seizures; severe or persistent drowsiness or dizziness; tremor; trouble urinating; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include deep sleep or loss of consciousness; hot or cool skin; fast or irregular heartbeat; large pupils; seizures; severe irritability, anxiety, or panicked feeling; slowed or shallow breathing; vomiting.

Proper storage of pseudoephedrine/methscopolamine sustained-release tablets:

Store pseudoephedrine/methscopolamine sustained-release tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep pseudoephedrine/methscopolamine sustained-release tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about pseudoephedrine/methscopolamine sustained-release tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Pseudoephedrine/methscopolamine sustained-release tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take pseudoephedrine/methscopolamine sustained-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pseudoephedrine/methscopolamine sustained-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pseudoephedrine/methscopolamine sustained-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pseudoephedrine/methscopolamine sustained-release tablets.

Issue Date: June 3, 2015

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.