Pseudoephedrine/ chlorpheniramine/ dextromethorphan tablets
Generic Name: pseudoephedrine/chlorpheniramine/dextromethorphan (SOO-doe-e-FED-rin/KLOR-fen-IR-a-meen/DEX-troe-meth-OR-fan)
Brand Name: Maxichlor PSE DM
Pseudoephedrine/ chlorpheniramine/ dextromethorphan tablets is used for:
Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.
Pseudoephedrine/chlorpheniramine/dextromethorphan tablets is a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.
Do NOT use pseudoephedrine/ chlorpheniramine/ dextromethorphan tablets if:
- you are allergic to any ingredient in pseudoephedrine/chlorpheniramine/dextromethorphan tablets
- you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, severe heart problems, stomach ulcer, or narrow-angle glaucoma
- you are unable to urinate or are having an asthma attack
- you are taking droxidopa or sodium oxybate (GHB), or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using pseudoephedrine/ chlorpheniramine/ dextromethorphan tablets:
Some medical conditions may interact with pseudoephedrine/chlorpheniramine/dextromethorphan tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a fast, slow, or irregular heartbeat
- if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your stomach, bladder, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; sleep apnea; mental or mood problems (eg, depression); or an overactive thyroid
- if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
- if you have a history of alcohol abuse, are in poor heath, are very overweight, or are confined to a bed
Some MEDICINES MAY INTERACT with pseudoephedrine/chlorpheniramine/dextromethorphan tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of pseudoephedrine/chlorpheniramine/dextromethorphan tablets's side effects
- Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
- Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by pseudoephedrine/chlorpheniramine/dextromethorphan tablets
- Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by pseudoephedrine/chlorpheniramine/dextromethorphan tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if pseudoephedrine/chlorpheniramine/dextromethorphan tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use pseudoephedrine/ chlorpheniramine/ dextromethorphan tablets:
Use pseudoephedrine/chlorpheniramine/dextromethorphan tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take pseudoephedrine/chlorpheniramine/dextromethorphan tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Take pseudoephedrine/chlorpheniramine/dextromethorphan tablets with a full glass of water (8 oz/240 mL).
- If you miss a dose of pseudoephedrine/chlorpheniramine/dextromethorphan tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use pseudoephedrine/chlorpheniramine/dextromethorphan tablets.
Important safety information:
- Pseudoephedrine/chlorpheniramine/dextromethorphan tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use pseudoephedrine/chlorpheniramine/dextromethorphan tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using pseudoephedrine/chlorpheniramine/dextromethorphan tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Do not take diet or appetite control medicines while you take pseudoephedrine/chlorpheniramine/dextromethorphan tablets without checking with your doctor.
- Pseudoephedrine/chlorpheniramine/dextromethorphan tablets has pseudoephedrine, chlorpheniramine, and dextromethorphan in it. Before you start any new medicine, check the label to see if it has pseudoephedrine, chlorpheniramine, or dextromethorphan in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Do not use pseudoephedrine/chlorpheniramine/dextromethorphan tablets for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.
- Contact your doctor if you have a sore throat that is severe, lasts more than 2 days, or occurs with fever, rash, headache, nausea, or vomiting.
- Tell your doctor if you have a fever that lasts more than 3 days or becomes worse.
- Contact your doctor if you have a cough that lasts more than 7 days or occurs with fever, rash, or persistent headache.
- Pseudoephedrine/chlorpheniramine/dextromethorphan tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to pseudoephedrine/chlorpheniramine/dextromethorphan tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Pseudoephedrine/chlorpheniramine/dextromethorphan tablets may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking pseudoephedrine/chlorpheniramine/dextromethorphan tablets for a few days before the tests.
- Pseudoephedrine/chlorpheniramine/dextromethorphan tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking pseudoephedrine/chlorpheniramine/dextromethorphan tablets.
- Tell your doctor or dentist that you take pseudoephedrine/chlorpheniramine/dextromethorphan tablets before you receive any medical or dental care, emergency care, or surgery.
- Use pseudoephedrine/chlorpheniramine/dextromethorphan tablets with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, drowsiness, dizziness, dry mouth, nervousness, sleeplessness, and trouble urinating.
- Caution is advised when using pseudoephedrine/chlorpheniramine/dextromethorphan tablets in CHILDREN; they may be more sensitive to its effects, especially excitability.
- Pseudoephedrine/chlorpheniramine/dextromethorphan tablets should not be used in CHILDREN younger than 6 years old without first checking with the child's doctor; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using pseudoephedrine/chlorpheniramine/dextromethorphan tablets while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking pseudoephedrine/chlorpheniramine/dextromethorphan tablets.
When used for long periods of time or at high doses, pseudoephedrine/chlorpheniramine/dextromethorphan tablets may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if pseudoephedrine/chlorpheniramine/dextromethorphan tablets stops working well. Do not take more than prescribed.
Some people who use pseudoephedrine/chlorpheniramine/dextromethorphan tablets for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.
If you stop taking pseudoephedrine/chlorpheniramine/dextromethorphan tablets suddenly, you may have WITHDRAWAL symptoms. These may include mental or mood changes (eg, depression).
Possible side effects of pseudoephedrine/ chlorpheniramine/ dextromethorphan tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; increased sweating; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest tightness; clumsiness or unsteadiness; difficulty urinating or inability to urinate; fast or irregular heartbeat; fever, chills, or sore throat; flushing or redness of the face; hallucinations; mental or mood changes; numbness or tingling; seizures; severe dizziness, drowsiness, lightheadedness, or headache; severe dryness of mouth, nose, and throat; severe or persistent trouble sleeping; shortness of breath; tremor; unusual bruising or bleeding; vision problems (eg, double vision, severe or persistent blurred vision).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; mental or mood changes; muscle spasms; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; trouble breathing; unusual eye movements; unusually fast, slow, or irregular heartbeat; vomiting.Proper storage of pseudoephedrine/chlorpheniramine/dextromethorphan tablets:
Store pseudoephedrine/chlorpheniramine/dextromethorphan tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep pseudoephedrine/chlorpheniramine/dextromethorphan tablets out of the reach of children and away from pets.
- If you have any questions about pseudoephedrine/chlorpheniramine/dextromethorphan tablets, please talk with your doctor, pharmacist, or other health care provider.
- Pseudoephedrine/chlorpheniramine/dextromethorphan tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take pseudoephedrine/chlorpheniramine/dextromethorphan tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pseudoephedrine/chlorpheniramine/dextromethorphan tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pseudoephedrine/chlorpheniramine/dextromethorphan tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pseudoephedrine/chlorpheniramine/dextromethorphan tablets.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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