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Pseudoephedrine/ brompheniramine/ dextromethorphan drops

Generic Name: pseudoephedrine/brompheniramine/dextromethorphan (SOO-doe-e-FED-rin/BROME-fen-IR-a-meen/DEX-troe-meth-OR-fan)
Brand Name: Resperal-DM Drops

Pseudoephedrine/ brompheniramine/ dextromethorphan drops are used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Pseudoephedrine/brompheniramine/dextromethorphan drops are a decongestant, antihistamine, and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing, while the cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use pseudoephedrine/ brompheniramine/ dextromethorphan drops if:

  • you are allergic to any ingredient in pseudoephedrine/brompheniramine/dextromethorphan drops
  • you have severe high blood pressure, severe heart blood vessel disease, or severe heart problems
  • you have narrow-angle glaucoma, ulcers, severe lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD)
  • you are unable to urinate or are having an asthma attack
  • you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using pseudoephedrine/ brompheniramine/ dextromethorphan drops:

Some medical conditions may interact with pseudoephedrine/brompheniramine/dextromethorphan drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat
  • if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma or increased pressure in the eye; a blockage of your stomach, bladder, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid
  • if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), COPD, or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with pseudoephedrine/brompheniramine/dextromethorphan drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attacks may be increased
  • Furazolidone, linezolid, or MAOIs (eg, phenelzine) because severe high blood pressure and fever may occur
  • Barbiturates (eg, phenobarbital), beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, MAOIs (eg, phenelzine), sodium oxybate (GHB), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, potassium citrate) because they may increase the risk of pseudoephedrine/brompheniramine/dextromethorphan drops's side effects, including severe drowsiness and trouble breathing
  • Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by pseudoephedrine/brompheniramine/dextromethorphan drops
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by pseudoephedrine/brompheniramine/dextromethorphan drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if pseudoephedrine/brompheniramine/dextromethorphan drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use pseudoephedrine/ brompheniramine/ dextromethorphan drops:

Use pseudoephedrine/brompheniramine/dextromethorphan drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take pseudoephedrine/brompheniramine/dextromethorphan drops by mouth with or without food.
  • Use the dropper that comes with pseudoephedrine/brompheniramine/dextromethorphan drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of pseudoephedrine/brompheniramine/dextromethorphan drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use pseudoephedrine/brompheniramine/dextromethorphan drops.

Important safety information:

  • Pseudoephedrine/brompheniramine/dextromethorphan drops may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use pseudoephedrine/brompheniramine/dextromethorphan drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not take diet or appetite control medicines while you are taking pseudoephedrine/brompheniramine/dextromethorphan drops without checking with your doctor.
  • Pseudoephedrine/brompheniramine/dextromethorphan drops has pseudoephedrine, dextromethorphan, and brompheniramine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine, dextromethorphan, or brompheniramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.
  • If you are scheduled for allergy skin testing, do not take pseudoephedrine/brompheniramine/dextromethorphan drops for several days before the test because it may decrease your response to the skin tests.
  • Tell your doctor or dentist that you take pseudoephedrine/brompheniramine/dextromethorphan drops before you receive any medical or dental care, emergency care, or surgery.
  • Use pseudoephedrine/brompheniramine/dextromethorphan drops with caution in CHILDREN and in the ELDERLY; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using pseudoephedrine/brompheniramine/dextromethorphan drops while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking pseudoephedrine/brompheniramine/dextromethorphan drops.

Possible side effects of pseudoephedrine/ brompheniramine/ dextromethorphan drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of pseudoephedrine/brompheniramine/dextromethorphan drops:

Store pseudoephedrine/brompheniramine/dextromethorphan drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep pseudoephedrine/brompheniramine/dextromethorphan drops out of the reach of children and away from pets.

General information:

  • If you have any questions about pseudoephedrine/brompheniramine/dextromethorphan drops, please talk with your doctor, pharmacist, or other health care provider.
  • Pseudoephedrine/brompheniramine/dextromethorphan drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take pseudoephedrine/brompheniramine/dextromethorphan drops or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pseudoephedrine/brompheniramine/dextromethorphan drops. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pseudoephedrine/brompheniramine/dextromethorphan drops. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pseudoephedrine/brompheniramine/dextromethorphan drops.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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