Prothrombin Complex Conc (Human) [(Factors II, VII, IX, X), Prot C, Prot S]
Generic Name: Prothrombin Complex Conc (Human) [(Factors II, VII, IX, X), Prot C, Prot S] (PRO throm bin KOM pleks KON cen trate HYU man FAK ters too SEV en nyne ten PROE teen cee & PROE teen ess)
Brand Name: Kcentra
- People are treated with drugs to thin the blood when they have health problems that raise the chance of blood clots. This medicine is used to undo the effects of those drugs. Very bad and sometimes deadly blood clots have happened after using prothrombin complex conc (human) [(factors II, VII, IX, X), prot C, prot S]. Talk with your doctor, if you have ever had a blood clot.
- Before you use this medicine, tell your doctor if you have had a heart attack, a blood problem called disseminated intravascular coagulation (DIC), stroke, chest pain, or very bad blood vessel disease within the past 3 months. You will need to talk about the benefits and risks of using prothrombin complex conc.
Uses of Prothrombin Complex Conc:
- It is used to undo the effects of certain blood thinners like warfarin.
What do I need to tell my doctor BEFORE I take Prothrombin Complex Conc?
- If you have an allergy to prothrombin complex, heparin, or any other part of this medicine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have had a low platelet count caused by heparin.
This is not a list of all drugs or health problems that interact with prothrombin complex conc.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Prothrombin Complex Conc?
- Tell all of your health care providers that you take prothrombin complex conc. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine is made from human plasma (part of the blood) and may have viruses that may cause disease. This medicine is screened, tested, and treated to lower the chance that it carries an infection. Talk with the doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Prothrombin Complex Conc) best taken?
Use prothrombin complex conc as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- A fast heartbeat.
- Very upset stomach or throwing up.
- Very bad dizziness or passing out.
- Fast breathing.
- Very bad headache.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Feeling very tired or weak.
- Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.
What are some other side effects of Prothrombin Complex Conc?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Prothrombin Complex Conc?
- If you need to store this medicine at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about prothrombin complex conc, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about prothrombin complex conc. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using prothrombin complex conc (human) [(factors II, VII, IX, X), prot C, prot S].
Review Date: December 6, 2017
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- Drug class: anticoagulant reversal agents
Other brands: Kcentra
- Prothrombin Complex Concentrate (Human) [(Factors II, VII, IX, X), Protein C, and Protein S] (Wolters Kluwer)