Medically reviewed by Drugs.com. Last updated on Dec 20, 2020.
- Very bad and sometimes deadly liver problems have happened with Promacta (eltrombopag tablets). Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- This medicine may raise the risk of liver failure when taken with interferon and ribavirin in patients with hepatitis C. If your doctor tells you to stop taking interferon and ribavirin, you will also need to stop taking Promacta (eltrombopag tablets).
Uses of Promacta:
- It is used to raise platelet counts.
- It is used to treat immune thrombocytopenia (ITP).
- It is used to treat aplastic anemia.
What do I need to tell my doctor BEFORE I take Promacta?
- If you have an allergy to eltrombopag or any other part of Promacta (eltrombopag tablets).
- If you are allergic to Promacta (eltrombopag tablets); any part of Promacta (eltrombopag tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have a low platelet count caused by some other health problems.
- If you are breast-feeding. Do not breast-feed while you take Promacta (eltrombopag tablets).
This is not a list of all drugs or health problems that interact with Promacta (eltrombopag tablets).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Promacta (eltrombopag tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Promacta?
- Tell all of your health care providers that you take Promacta (eltrombopag tablets). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Do not stop taking Promacta (eltrombopag tablets) without calling your doctor. You may have a greater risk of very low platelets and bleeding. If you need to stop Promacta (eltrombopag tablets), talk with your doctor.
- This medicine may make cataracts worse or may raise the chance of new cataracts. Talk with the doctor.
- Have an eye exam as you have been told by your doctor.
- If you are of East Asian descent, talk with your doctor.
- Blood clots have happened with Promacta (eltrombopag tablets). Sometimes, blood clots like heart attack and stroke have been deadly. Talk with the doctor.
- Use care to prevent injury and avoid falls or crashes.
- This medicine is not for use in people with a certain bone marrow problem called myelodysplastic syndrome (MDS). If you have MDS and you take Promacta (eltrombopag tablets), MDS may get worse and turn into a type of blood cancer called acute myelogenous leukemia (AML). If MDS turns into AML, you could die sooner from AML. If you have MDS, talk with your doctor.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- Women must use birth control while taking Promacta (eltrombopag tablets) and for some time after the last dose. Ask your doctor how long to use birth control. If you get pregnant, call your doctor right away.
How is this medicine (Promacta) best taken?
Use Promacta (eltrombopag tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take on an empty stomach. Take 1 hour before or 2 hours after meals.
- Take Promacta (eltrombopag tablets) at least 2 hours before or 4 hours after any antacids; dairy products or other foods with calcium in them; or products that have calcium, iron, aluminum, magnesium, selenium, or zinc.
- Swallow whole. Do not chew, break, or crush.
- Do not mix with food or drinks.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
- Feeling very tired or weak.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Change in eyesight, eye pain, or very bad eye irritation.
- Any bruising or bleeding while you take and after you stop taking Promacta (eltrombopag tablets).
- Feeling confused.
- Swelling of belly.
- Swelling in the arms or legs.
- Fever or chills.
- Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.
What are some other side effects of Promacta?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Trouble sleeping.
- Not hungry.
- Flu-like signs.
- Upset stomach or throwing up.
- Stomach pain or diarrhea.
- Feeling dizzy, tired, or weak.
- Muscle or joint pain.
- Signs of a common cold.
- Hair loss.
- Muscle spasm.
- Nose or throat irritation.
- Mouth pain.
- Tooth pain.
- Change in color of skin.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Promacta?
- Store at room temperature.
- Store in the original container. Do not take out the antimoisture cube or packet.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Promacta (eltrombopag tablets) is refilled. If you have any questions about Promacta (eltrombopag tablets), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
More about Promacta (eltrombopag)
- Side Effects
- During Pregnancy
- Dosage Information
- Patient Tips
- Drug Images
- Drug Interactions
- Compare Alternatives
- Pricing & Coupons
- En Español
- 9 Reviews
- Drug class: platelet-stimulating agents
- FDA Approval History
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