Skip to Content

Prolex DM

Generic Name: dextromethorphan/potassium guaiacolsulfonate (DEX-troe-meth-OR-fan/poe-TASS-ee-um gywe-a-kole-SUL-foe-nate)
Brand Name: Examples include Guiadex DM and Prolex DM

Prolex DM is used for:

Temporarily relieving cough due to minor throat and airway irritation associated with upper respiratory tract infections or inhaled irritants.

Prolex DM is a combination of an expectorant and a cough suppressant. It works by loosening mucus and lung secretions in the chest and making coughs more productive.

Do NOT use Prolex DM if:

  • you are allergic to any ingredient in Prolex DM
  • you have taken a monoamine oxidase (MAO) inhibitor (eg, selegiline) within the last 14 days
  • you are taking a selective serotonin reuptake inhibitor (SSRI) (eg, fluoxetine)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Prolex DM:

Some medical conditions may interact with Prolex DM. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have chronic cough, chronic bronchitis, or any breathing problems, such as asthma, emphysema, or chronic obstructive pulmonary disease (COPD)

Some MEDICINES MAY INTERACT with Prolex DM. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • MAO inhibitors (eg, selegiline) and SSRIs (eg, fluoxetine) because the risk of toxic side effects may be increased by Prolex DM

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prolex DM may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Prolex DM:

Use Prolex DM as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Prolex DM may be taken with or without food. Take with food if stomach upset occurs.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure this dose.
  • To help Prolex DM work, drink plenty of extra fluids while taking Prolex DM, unless your health care provider instructed otherwise.
  • If you miss a dose of Prolex DM and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Prolex DM.

Important safety information:

  • Prolex DM may cause drowsiness, dizziness, blurred vision, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Prolex DM. Using Prolex DM alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • If your cough lasts for more than 1 week or comes back, or if you also have a fever, rash, or persistent headache, contact your health care provider. A persistent cough could be a sign of a serious condition.
  • Prolex DM contains dextromethorphan. Before you being taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains dextromethorphan. If it does or if you are not sure, contact your health care provider or pharmacist.
  • Diabetes patients - Some brands of Prolex DM may contain sugar and affect your blood sugar level. Read the label carefully before using Prolex DM.
  • Prolex DM is not recommended for use in CHILDREN younger than 3 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Prolex DM, discuss with your doctor the benefits and risks of using Prolex DM during pregnancy. It is unknown if Prolex DM is excreted in breast milk. If you are or will be breast-feeding while you are using Prolex DM, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Prolex DM:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; excitement; hallucinations; slowed breathing.

Proper storage of Prolex DM:

Store Prolex DM at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Prolex DM out of the reach of children and away from pets.

General information:

  • If you have any questions about Prolex DM, please talk with your doctor, pharmacist, or other health care provider.
  • Prolex DM is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Prolex DM or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Prolex DM. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Prolex DM. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Prolex DM.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

More about Prolex DM (dextromethorphan / potassium guaiacolsulfonate)

Consumer resources

Hide