Prolastin-C (Alpha-Proteinase Inhibitor Solution for Injection)
Medically reviewed on July 4, 2018
Uses of Prolastin-C:
- It is used to treat emphysema caused by alpha1-antitrypsin deficiency.
What do I need to tell my doctor BEFORE I take Prolastin-C?
- If you have an allergy to alpha1-proteinase inhibitor or any other part of Prolastin-C (alpha-proteinase inhibitor solution for injection).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have IgA deficiency.
This is not a list of all drugs or health problems that interact with Prolastin-C (alpha-proteinase inhibitor solution for injection).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Prolastin-C (alpha-proteinase inhibitor solution for injection) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Prolastin-C?
- Tell all of your health care providers that you take Prolastin-C (alpha-proteinase inhibitor solution for injection). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Check blood pressure and heart rate as the doctor has told you. Talk with the doctor.
- Allergic side effects may rarely happen.
- This medicine is made from human plasma (part of the blood) and may have viruses that may cause disease. This medicine is screened, tested, and treated to lower the chance that it carries an infection. Talk with the doctor.
- Your doctor will give you another drug (epinephrine) to use in case of an allergic reaction. Be sure you know how and when to use it. Certain drugs may make epinephrine not work as well or raise the chance of side effects. This includes some drugs used to treat depression, heart problems, or high blood pressure. There are many drugs that interact with epinephrine. Talk with your doctor or pharmacist to make sure it is safe to take epinephrine with all of your drugs.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Prolastin-C (alpha-proteinase inhibitor solution for injection) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Prolastin-C) best taken?
Use Prolastin-C (alpha-proteinase inhibitor solution for injection) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Wash your hands before use.
- Wear gloves when preparing and giving a dose.
- Before giving the shot, let it come to room temperature. Do not heat Prolastin-C (alpha-proteinase inhibitor solution for injection).
- This product is clear but may contain a few particles. Do not use if the solution is cloudy, leaking, or has more than a few particles.
- This medicine is colorless to yellow-green. Do not use if the solution changes color.
- Do not mix with any other liquid drugs.
- Use within 3 hours of putting a needle into the vial.
- Do not shake.
- Throw away any part not used after use.
- Keep track of each infusion. Write down the product lot number and expiration date. Write down the date, the time the infusion started and ended, where the infusion was used, and any side effects you had.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of certain infections (parvovirus B19, hepatitis A) like fever or chills, feeling very sleepy, runny nose, rash, joint pain, tiredness, poor appetite, upset stomach or throwing up, belly pain, or yellow skin or eyes.
- Chest pain or pressure.
- Very bad dizziness or passing out.
- Shortness of breath.
- Pain when passing urine or blood in urine.
- If your chronic obstructive pulmonary disease (COPD) gets worse or you have a cough or trouble breathing.
What are some other side effects of Prolastin-C?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Signs of a common cold.
- Sinus pain.
- Feeling tired or weak.
- Loose stools (diarrhea).
- Muscle pain.
- Upset stomach.
- Runny nose.
- Irritation where Prolastin-C (alpha-proteinase inhibitor solution for injection) is used.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Prolastin-C?
- Store in a refrigerator or at room temperature. If stored at room temperature, throw away any part not used after 1 month.
- Store in original container.
- Do not freeze.
- Do not put Prolastin-C (alpha-proteinase inhibitor solution for injection) back in the refrigerator after it has been stored at room temperature.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Prolastin-C (alpha-proteinase inhibitor solution for injection), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Prolastin-C (alpha 1-proteinase inhibitor)
- Prolastin-C Side Effects
- During Pregnancy
- Dosage Information
- Compare Alternatives
- Pricing & Coupons
- En Español
- 2 Reviews
- Drug class: miscellaneous respiratory agents
- Prolastin-C (Alpha-Proteinase Inhibitor Powder for Injection)
- Prolastin-C (Advanced Reading)