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Pomalyst

Generic Name: Pomalidomide (poe ma LID oh mide)
Brand Name: Pomalyst

  • Do not take Pomalyst (pomalidomide) if you are pregnant. Use during pregnancy may cause birth defects or loss of the unborn baby. If you get pregnant while taking this medicine or within 4 weeks after care ends, call your doctor right away.
  • You must have 2 pregnancy tests that show you are NOT pregnant before starting Pomalyst. You must have pregnancy tests done while taking this medicine. Talk with your doctor.
  • Use 2 kinds of birth control that you can trust for at least 4 weeks before care begins, during care, and for at least 4 weeks after care ends.
  • The chance of blood clots may be raised with Pomalyst in certain patients. This may be blood clots in the arms, legs, or lungs; heart attack; or stroke. Your doctor may have you take a blood thinner to prevent blood clots. Follow what your doctor has told you to do. Call your doctor right away if you have any chest pain or pressure; coughing up blood; shortness of breath; or pain, warmth, or swelling of the legs or arms. Call your doctor right away if you have signs of heart attack like chest pain that may spread to the arms, neck, jaw, back, or stomach; sweating that is not normal; or feeling sick or throwing up. Call your doctor right away if you have signs of stroke like change in strength on 1 side is greater than the other; eyesight, speech, or balance problems; change in thinking clearly and with logic; or very bad headache.
  • You may only get this medicine through a special program. Talk with your doctor.

Uses of Pomalyst:

  • It is used to treat multiple myeloma.

What do I need to tell my doctor BEFORE I take Pomalyst?

  • If you have an allergy to pomalidomide or any other part of Pomalyst.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are of childbearing age, but are not using 2 kinds of birth control or if you are planning to get pregnant during your care or within 4 weeks after care has ended.
  • If you are breast-feeding. Do not breast-feed while you take this medicine.

This is not a list of all drugs or health problems that interact with Pomalyst.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Pomalyst?

  • Tell all of your health care providers that you take Pomalyst. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine affects you.
  • Do not donate blood while using Pomalyst and for 1 month after stopping.
  • If you smoke, talk with your doctor.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
  • If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
  • Patients with cancer who take this medicine may be at a greater risk of getting a bad health problem called tumor lysis syndrome (TLS). Sometimes, this has been deadly. Call your doctor right away if you have a fast heartbeat or a heartbeat that does not feel normal; any passing out; trouble passing urine; muscle weakness or cramps; upset stomach, throwing up, loose stools, or not able to eat; or feel sluggish.
  • This medicine may add to the chance of getting some types of cancer. Talk with the doctor.
  • If you are 65 or older, use Pomalyst (pomalidomide) with care. You could have more side effects.
  • This medicine may cause you to not be able to get pregnant. Talk with the doctor.
  • If you have sex without using 2 kinds of birth control that you can trust, if you think you may be pregnant, or if you miss your period, call your doctor right away.
  • If you are a man and have sex with a pregnant female or a female who can get pregnant, always use a latex or synthetic condom during sex. Do this even if you have had a vasectomy. Use a latex or synthetic condom during care, during any breaks in care, and for at least 4 weeks after care ends.
  • If you are a man and have unprotected sex with a female who is or could get pregnant, or your female partner gets pregnant within 4 weeks of your last dose, call your doctor right away.
  • If you are a man, do not donate sperm while using this medicine and for 1 month after stopping.

How is this medicine (Pomalyst) best taken?

Use Pomalyst as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food.
  • Take with a full glass of water.
  • Take this medicine at the same time of day.
  • Swallow whole. Do not chew, break, or crush.
  • Do not open the capsules.
  • If you touch a broken capsule, or the drug inside the capsule, wash the area with soap and water.
  • If a broken capsule or the drug inside the capsule touches your eyes, rinse your eyes right away with water.
  • If you are on dialysis and are taking Pomalyst on the day you get dialysis, take it after your dialysis. If you have questions, talk with your doctor.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it and go back to your normal time.
  • If it has been 12 hours or more since the missed dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
  • Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
  • Signs of lung or breathing problems like shortness of breath or other trouble breathing, cough, or fever.
  • A burning, numbness, or tingling feeling that is not normal.
  • Feeling very tired or weak.
  • Feeling confused.
  • Swelling in the arms or legs.
  • Chest pain.
  • Shakiness.
  • Very bad and sometimes deadly liver problems have happened with this medicine. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

What are some other side effects of Pomalyst?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling tired or weak.
  • Hard stools (constipation).
  • Loose stools (diarrhea).
  • Upset stomach or throwing up.
  • Back pain.
  • Dizziness.
  • Bone or joint pain.
  • Muscle pain or weakness.
  • Muscle spasm.
  • Not hungry.
  • Headache.
  • Weight loss.
  • Anxiety.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Pomalyst?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Pomalyst is refilled. If you have any questions about this medicine, please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Pomalyst or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Pomalyst. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

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