Generic Name: Pertuzumab (per TU zoo mab)
Brand Name: Perjeta
Medically reviewed on Sep 5, 2018
- This medicine may cause heart failure. You will need to have your heart function checked while taking pertuzumab. Call your doctor right away if you have signs of heart problems like a cough or shortness of breath that is new or worse, swelling of the ankles or legs, a heartbeat that does not feel normal, weight gain of more than 5 pounds in 24 hours, dizziness, or passing out.
- This medicine with trastuzumab may cause harm to the unborn baby or loss of the unborn baby if used during pregnancy or within 7 months after the last dose.
- Use birth control that you can trust to prevent pregnancy while taking pertuzumab and for at least 7 months after stopping pertuzumab.
- If you get pregnant while taking pertuzumab or within 7 months after your last dose, call your doctor right away.
Uses of Pertuzumab:
- It is used to treat breast cancer.
What do I need to tell my doctor BEFORE I take Pertuzumab?
- If you have an allergy to pertuzumab or any other part of pertuzumab.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are breast-feeding. Do not breast-feed while you take pertuzumab. You will also need to avoid breast-feeding after you stop pertuzumab until there is no more of pertuzumab in your body. Talk with your doctor to see how long you need to avoid breast-feeding after you stop this drug.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take pertuzumab with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Pertuzumab?
- Tell all of your health care providers that you take pertuzumab. This includes your doctors, nurses, pharmacists, and dentists.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
- Some patients have very bad side effects during the infusion. Tell your doctor if you have any bad effects during the infusion.
- This medicine may raise the chance of a very bad and sometimes deadly heart problem (myocarditis). The chance may be higher if you are getting certain other chemo drugs. Talk with your doctor.
- You will need to have heart function tests while taking pertuzumab. Talk with the doctor.
- If you are 65 or older, use pertuzumab with care. You could have more side effects.
- If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting pertuzumab. Talk with your doctor.
How is this medicine (Pertuzumab) best taken?
Use pertuzumab as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Chest pain or pressure or a fast heartbeat.
- Very bad headache.
- Very upset stomach or throwing up.
- Very loose stools (diarrhea).
- Any unexplained bruising or bleeding.
- Feeling very tired or weak.
- A burning, numbness, or tingling feeling that is not normal.
What are some other side effects of Pertuzumab?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Loose stools (diarrhea).
- Upset stomach or throwing up.
- Belly pain.
- Mouth irritation or mouth sores.
- Not hungry.
- Bad taste in your mouth.
- Dry skin.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Pertuzumab?
- If you need to store pertuzumab at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about pertuzumab, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about pertuzumab
- Pertuzumab Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- Drug class: HER2 inhibitors
Other brands: Perjeta