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Pentetate zinc trisodium (Zn-DTPA)

Generic Name: pentetate zinc trisodium (zn-dtpa) (PEN-teh-tate zingk try-SO-dee-uhm)
Brand Name: Generic only. No brands available.

Pentetate zinc trisodium (Zn-DTPA) is used for:

Treating certain kinds of radiation contamination.

Pentetate zinc trisodium (Zn-DTPA) is a chelating agent. It works by removing certain radioactive chemicals from the body. This lowers the risk of possible future side effects, such as cancer, which may occur years after exposure.

Do NOT use pentetate zinc trisodium (Zn-DTPA) if:

  • you are allergic to any ingredient in pentetate zinc trisodium (Zn-DTPA)

Contact your doctor or health care provider right away if any of these apply to you.

Before using pentetate zinc trisodium (Zn-DTPA):

Some medical conditions may interact with pentetate zinc trisodium (Zn-DTPA). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have asthma, kidney problems, or low magnesium or manganese levels in the blood

Some MEDICINES MAY INTERACT with pentetate zinc trisodium (Zn-DTPA). However, no specific interactions with pentetate zinc trisodium (Zn-DTPA) are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if pentetate zinc trisodium (Zn-DTPA) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use pentetate zinc trisodium (Zn-DTPA):

Use pentetate zinc trisodium (Zn-DTPA) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Pentetate zinc trisodium (Zn-DTPA) is usually administered at your doctor's office, hospital, or clinic.
  • Pentetate zinc trisodium (Zn-DTPA) is usually given as an injection but it may also be given by the inhalation route. If pentetate zinc trisodium (Zn-DTPA) is taken by the inhalation route, coughing and wheezing may occur.
  • Drink plenty of fluids and urinate often.
  • If you miss a dose of pentetate zinc trisodium (Zn-DTPA), contact your doctor immediately.

Ask your health care provider any questions you may have about how to use pentetate zinc trisodium (Zn-DTPA).

Important safety information:

  • Radioactive materials are removed in urine, feces, and breast milk. Pentetate zinc trisodium (Zn-DTPA) helps to remove radioactive chemicals from the urine. Practice safety measures to avoid contaminating other people.
  • Use a toilet instead of a urinal, and flush it several times after each use. Clean spilled urine or feces completely and wash your hands well. If blood or urine touches clothing or linens, wash them separately.
  • If you are coughing, dispose of any mucus carefully. If possible, avoid swallowing mucus. Talk to your doctor if you are coughing.
  • Parents or child caregivers - Be very careful in handling the urine, feces, and mucus of children to avoid any extra exposure to either you or the child.
  • LAB TESTS, including complete blood cell counts, urinalysis, kidney function, and blood electrolyte and essential metal counts, will be required to monitor your progress before and during treatment. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant or think you may be pregnant, tell your doctor before using pentetate zinc trisodium (Zn-DTPA). Women who have or may have been exposed to radioactive chemicals should not breast-feed, whether or not they are receiving this treatment with medicine. Take extra care in disposing of breast milk.

Possible side effects of pentetate zinc trisodium (Zn-DTPA):

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Coughing; headache; lightheadedness; pelvic pain; wheezing.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of pentetate zinc trisodium (Zn-DTPA):

Pentetate zinc trisodium (Zn-DTPA) is usually handled and stored by a health care provider. If you are using pentetate zinc trisodium (Zn-DTPA) at home, store pentetate zinc trisodium (Zn-DTPA) as directed by your pharmacist or health care provider. Keep pentetate zinc trisodium (Zn-DTPA) out of the reach of children and away from pets.

General information:

  • If you have any questions about pentetate zinc trisodium (Zn-DTPA), please talk with your doctor, pharmacist, or other health care provider.
  • Pentetate zinc trisodium (Zn-DTPA) is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take pentetate zinc trisodium (Zn-DTPA) or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pentetate zinc trisodium (Zn-DTPA). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pentetate zinc trisodium (Zn-DTPA). This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pentetate zinc trisodium (Zn-DTPA).

Issue Date: June 3, 2015

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.