Pasireotide Extended-Release Injection
Generic Name: Pasireotide Extended-Release Injection (pas i REE oh tide)
Brand Name: Signifor
Medically reviewed by Drugs.com. Last updated on July 3, 2020.
Uses of Pasireotide Extended-Release Injection:
- It is used to treat Cushing's disease.
- It is used to treat acromegaly.
What do I need to tell my doctor BEFORE I take Pasireotide Extended-Release Injection?
- If you have an allergy to pasireotide or any other part of pasireotide extended-release injection.
- If you are allergic to pasireotide extended-release injection; any part of pasireotide extended-release injection; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have any of these health problems: Low potassium or magnesium levels.
- If you have high blood sugar (diabetes).
- If you have liver disease.
- If you are breast-feeding or plan to breast-feed.
This is not a list of all drugs or health problems that interact with pasireotide extended-release injection.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take pasireotide extended-release injection with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Pasireotide Extended-Release Injection?
- Tell all of your health care providers that you take pasireotide extended-release injection. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You will need an ECG before starting pasireotide extended-release injection. You may also need to have an ECG while using pasireotide extended-release injection. Talk with your doctor.
- High blood sugar has happened with pasireotide extended-release injection. This includes diabetes that is new or worse.
- Check your blood sugar as you have been told by your doctor.
- Tell your doctor if you have signs of high or low blood sugar like breath that smells like fruit, dizziness, fast breathing, fast heartbeat, feeling confused, feeling sleepy, feeling weak, flushing, headache, more thirsty or hungry, passing urine more often, shaking, or sweating.
- Gallbladder problems have happened. Sometimes, people had to be treated in the hospital. In some cases the gallbladder had to be removed. Discuss any questions with the doctor.
- If you have not been through menopause and are able to get pregnant, talk with your doctor. The use of pasireotide extended-release injection may lead to being more fertile or unplanned pregnancy.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking pasireotide extended-release injection, call your doctor right away.
How is this medicine (Pasireotide Extended-Release Injection) best taken?
Use pasireotide extended-release injection as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a muscle.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of gallbladder problems like pain in the upper right belly area, right shoulder area, or between the shoulder blades; yellow skin or eyes; fever with chills; bloating; or very upset stomach or throwing up.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Slow heartbeat.
- Swelling of belly.
- Swelling in the arms or legs.
- This medicine may lower the amount of certain hormones in your body. Call your doctor right away if you have abnormal diarrhea, dizziness, feeling tired or weak, nausea, not hungry, passing out, throwing up, or weight loss.
- A type of abnormal heartbeat (prolonged QT interval) can happen with pasireotide extended-release injection. Call your doctor right away if you have a fast heartbeat, a heartbeat that does not feel normal, or if you pass out.
What are some other side effects of Pasireotide Extended-Release Injection?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Stomach pain or diarrhea.
- Hair loss.
- Nose or throat irritation.
- Irritation where the shot is given.
- Muscle or joint pain.
- Flu-like signs.
- Signs of a common cold.
- Back pain.
- Pain in arms or legs.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Pasireotide Extended-Release Injection?
- If you need to store pasireotide extended-release injection at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about pasireotide extended-release injection, please talk with your doctor, nurse, pharmacist, or other health care provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about pasireotide
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- En Español
- Drug class: somatostatin and somatostatin analogs