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Papain/ urea/ chlorophyllin spray

Generic Name: papain/urea/chlorophyllin (pap-ANE/you-REE-ah/KLOR-oh-FILL-in)
Brand Name: Panafil

Papain/ urea/ chlorophyllin spray is used for:

Removing dead tissue and thinning the pus in lesions such as ulcers, burns, wounds, and carbuncles.

Papain/urea/chlorophyllin spray is a debriding agent. It works by helping the breakdown of dead skin and pus, which helps improve the recovery time of open wounds. It also helps to control wound inflammation and odor.

Do NOT use papain/ urea/ chlorophyllin spray if:

  • you are allergic to any ingredient in papain/urea/chlorophyllin spray

Contact your doctor or health care provider right away if any of these apply to you.

Before using papain/ urea/ chlorophyllin spray:

Some medical conditions may interact with papain/urea/chlorophyllin spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with papain/urea/chlorophyllin spray. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Medicines containing silver, lead, or mercury because they may decrease papain/urea/chlorophyllin spray's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if papain/urea/chlorophyllin spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use papain/ urea/ chlorophyllin spray:

Use papain/urea/chlorophyllin spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Papain/urea/chlorophyllin spray is for external use only.
  • Before each use of papain/urea/chlorophyllin spray, clean the affected area with saline or another mild wound cleansing solution. Do not use hydrogen peroxide.
  • The first time papain/urea/chlorophyllin spray is used, prime the pump by holding the spray bottle upright directly over the wound and pumping 8 to 12 times.
  • Shake well before each use.
  • Hold the spray bottle about 1 to 2 inches from the wound and use even, firm pressure to spray the medicine. When sprayed, the medicine should cover an area about the size of a nickel. Completely cover the wound with medicine. The wound should not be visible under the medicine. Cover with appropriate dressing (eg, bandages) and secure into place. Wash the lesion each time the dressing is changed.
  • Wipe the nozzle with clean gauze after each use.
  • Change wound dressings according to the schedule set by your doctor.
  • If irritation occurs, talk with your doctor about changing the dressings more often.
  • If you miss a dose of papain/urea/chlorophyllin spray, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use papain/urea/chlorophyllin spray.

Important safety information:

  • Papain/urea/chlorophyllin spray is for external use only. Do not get it in the eyes or mouth. If you get papain/urea/chlorophyllin spray in the eyes, rinse them immediately with a generous amount of cool water.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using papain/urea/chlorophyllin spray while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use papain/urea/chlorophyllin spray, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of papain/ urea/ chlorophyllin spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild skin irritation; temporary burning sensation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of papain/urea/chlorophyllin spray:

Store papain/urea/chlorophyllin spray at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep papain/urea/chlorophyllin spray out of the reach of children and away from pets.

General information:

  • If you have any questions about papain/urea/chlorophyllin spray, please talk with your doctor, pharmacist, or other health care provider.
  • Papain/urea/chlorophyllin spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take papain/urea/chlorophyllin spray or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about papain/urea/chlorophyllin spray. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to papain/urea/chlorophyllin spray. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using papain/urea/chlorophyllin spray.

Issue Date: June 3, 2015

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.