Generic Name: Palbociclib (pal boe SYE klib)
Brand Name: Ibrance
Medically reviewed on Sep 5, 2018
Uses of Palbociclib:
- It is used to treat breast cancer.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Palbociclib?
- If you have an allergy to palbociclib or any part of palbociclib.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are taking any of these drugs: Carbamazepine, enzalutamide, phenytoin, rifampin, or St. John's wort.
- If you are breast-feeding. Do not breast-feed while you take palbociclib and for 3 weeks after your last dose.
This is not a list of all drugs or health problems that interact with palbociclib.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take palbociclib with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Palbociclib?
- Tell all of your health care providers that you take palbociclib. This includes your doctors, nurses, pharmacists, and dentists.
- You may have more of a chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Some infections have been very bad and even deadly.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking palbociclib with your other drugs.
- This medicine is taken with other drugs. Be sure you know about the warnings, benefits, and risks of these other drugs. Talk with the doctor if you have questions or concerns about any of the drugs.
- This medicine may affect being able to father a child. Talk with the doctor.
- If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for 3 months after care ends. Use birth control that you can trust.
- If you are a man and your sex partner gets pregnant while you take palbociclib or within 3 months after your last dose, call your doctor right away.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting palbociclib. Talk with your doctor.
- Use birth control that you can trust to prevent pregnancy while taking palbociclib and for at least 3 weeks after your last dose.
- If you get pregnant while taking palbociclib or within 3 weeks after your last dose, call your doctor right away.
How is this medicine (Palbociclib) best taken?
Use palbociclib as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Follow how to take palbociclib as you have been told by your doctor. Do not use more than you were told to use.
- Take palbociclib with food.
- Swallow whole. Do not chew, open, or crush.
- Do not take capsules that are broken, cracked, or look damaged.
- Avoid grapefruit and grapefruit juice.
- Avoid pomegranate, Seville oranges, and star fruit.
- Take palbociclib at the same time of day.
- To gain the most benefit, do not miss doses.
- Keep taking palbociclib as you have been told by your doctor or other health care provider, even if you feel well.
- If you throw up after taking a dose, do not repeat the dose. Take your next dose at your normal time.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Any unexplained bruising or bleeding.
- Shortness of breath.
- Feeling very tired or weak.
What are some other side effects of Palbociclib?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Not hungry.
- Loose stools (diarrhea).
- Hair thinning.
- Hair loss.
- Mouth irritation or mouth sores.
- Upset stomach or throwing up.
- Feeling tired or weak.
- Dry skin.
- Change in taste.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Palbociclib?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about palbociclib, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about palbociclib
- Palbociclib Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- 36 Reviews
- Drug class: CDK 4/6 inhibitors
Other brands: Ibrance