Generic Name: prednisolone sodium phosphate (pred-NIS-oh-lone)
Brand Name: Orapred ODT
Orapred ODT is used for:
Treating severe inflammatory conditions including allergies, arthritis, asthma, or skin reactions. It may also be used to treat certain blood, adrenal gland, eye, respiratory, or bowel conditions. It may also be used for other conditions as determined by your doctor.
Orapred ODT is a corticosteroid. It works by modifying the body's immune response to various conditions and decreasing inflammation.
Do NOT use Orapred ODT if:
- you are allergic to any ingredient in Orapred ODT
- you have a systemic fungal infection, a malaria infection of the brain, inflammation of the optic nerve, or a herpes infection of the eye
- you are scheduled to have a live or attenuated live vaccination (eg, smallpox)
- you are taking mifepristone
Contact your doctor or health care provider right away if any of these apply to you.
Before using Orapred ODT:
Some medical conditions may interact with Orapred ODT. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of heart problems (eg, congestive heart failure), heart attack, high blood pressure, kidney problems, liver problems (eg, cirrhosis), diabetes, seizures, an underactive or overactive thyroid, adrenal gland problems, or any mental or mood problems (eg, depression, psychosis)
- if you have or have recently had a fungal or bacterial infection, viral infection (eg, chickenpox, measles, shingles), yeast infection, threadworm infection, or any other type of infection
- if you have a herpes infection of the eye or increased pressure in the eye
- if you have HIV infection or tuberculosis (TB) infection, or if you have had ever had a positive TB skin test
- if you have any stomach problems (eg, ulcers), bowel problems (eg, blockage, perforation, or infection; diverticulitis; ulcerative colitis), recent intestinal surgery, or inflammation of the esophagus
- if you are postmenopausal or have weak bones (eg, osteoporosis) or muscle problems (eg, myasthenia gravis)
- if you have had a recent vaccination (eg, smallpox)
- if you have unexplained diarrhea or have recently traveled out of the country (eg, tropical areas)
- if you have low blood calcium or potassium levels or are experiencing stress (eg, illness, surgery)
Some MEDICINES MAY INTERACT with Orapred ODT. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Barbiturates (eg, phenobarbital), carbamazepine, ephedrine, hydantoins (eg, phenytoin), or rifampin because they may decrease Orapred ODT's effectiveness
- Certain anticholinesterases (eg, neostigmine) because severe muscle weakness in patients who have myasthenia gravis could occur
- Clarithromycin, cyclosporine, estrogens (eg, estradiol), oral contraceptives (eg, birth control pills), or pancuronium because they may increase the risk of Orapred ODT's side effects
- Amphotericin B, anticholinesterases (eg, pyridostigmine), digitalis glycosides (eg, digoxin), diuretics, (eg, hydrochlorothiazide), furosemide, live or attenuated live vaccines, methotrexate, mifepristone, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), ritodrine, or salicylates (eg, aspirin) because the risk of their side effects may be increased by Orapred ODT
- Anticoagulants (eg, warfarin) or killed or inactivated vaccines because their effectiveness may be decreased by Orapred ODT
This may not be a complete list of all interactions that may occur. Ask your health care provider if Orapred ODT may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Orapred ODT:
Use Orapred ODT as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Orapred ODT by mouth with food.
- Swallow Orapred ODT whole. Do not break, crush, or chew before swallowing. Do not use partial tablets.
- Do not remove the blister from the outer pouch until you are ready to take Orapred ODT. Make sure that your hands are dry when you open the blister pack. Do not push the tablet through the foil. Peel back the foil on the blister pack and place the tablet on your tongue. The tablet dissolves quickly and can be swallowed with saliva. The medicine may be taken with or without water. Take the tablet immediately after opening the blister pack. Do not store the removed tablet for future use.
- If you miss a dose of Orapred ODT, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Orapred ODT.
Important safety information:
- Orapred ODT may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
- Orapred ODT may interfere with skin allergy tests. If you are scheduled for a skin test, talk to you doctor. You may need to stop taking Orapred ODT for a few days before the tests.
- Do not receive a live vaccine (eg, measles, mumps) while you are taking Orapred ODT. Talk with your doctor before you receive any vaccine.
- Tell your doctor or dentist that you take Orapred ODT before you receive any medical or dental care, emergency care, or surgery.
- Orapred ODT is a corticosteroid. Before you start any new medicine, check the label to see if it has a corticosteroid in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Diabetes patients - Orapred ODT may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Lab tests, including adrenal function tests, may be performed while you use Orapred ODT. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Orapred ODT with caution in the ELDERLY; they may be more sensitive to its effects, especially an increased risk of bone weakness or fracture.
- Caution is advised when using Orapred ODT in CHILDREN; they may be more sensitive to its effects.
- Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they take Orapred ODT.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Orapred ODT while you are pregnant. Orapred ODT is found in breast milk. If you are or will be breast-feeding while you use Orapred ODT, check with your doctor. Discuss any possible risks to your baby.
If you stop taking Orapred ODT suddenly, you may have WITHDRAWAL symptoms. These may include fever, vomiting, appetite loss, diarrhea, nausea, dizziness, weight loss, weakness, general body discomfort, or joint or muscle pain.
Possible side effects of Orapred ODT:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; facial flushing; headache; increased appetite; increased sweating; lightheadedness; nausea; nervousness; upset stomach.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; changes in body fat; changes in menstrual period; changes in skin color; depression; fever, chills, or sore throat; lesions in the mouth or throat; mental or mood changes; muscle pain or weakness; seizures; severe nausea or vomiting; severe stomach or back pain; sudden severe dizziness or headache; swelling of the ankles, feet, or hands; tendon or bone pain; thinning of skin; trouble sleeping; unusual weight gain; vision changes or other eye problems; vomit that looks like coffee grounds.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Orapred ODT:
Store Orapred ODT at room temperature, between 68 and 77 degrees F (20 to 25 degrees C). Store in the original packaging until just before use. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Orapred ODT out of the reach of children and away from pets.
- If you have any questions about Orapred ODT, please talk with your doctor, pharmacist, or other health care provider.
- Orapred ODT is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Orapred ODT or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Orapred ODT. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Orapred ODT. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Orapred ODT.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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- Drug class: glucocorticoids