Generic Name: omeprazole (oh-MEP-ra-zole)
Brand Name: First-Omeprazole
Omeprazole suspension is used for:
Treating heartburn or irritation of the esophagus caused by gastroesophageal reflux disease (GERD). It may also be used for short-term treatment of ulcers of the stomach or small intestine. It may also be used with certain antibiotics to treat ulcers of the small intestines and to help prevent them from coming back. It may also be used to treat conditions that cause your body to make too much stomach acid (eg, Zollinger-Ellison syndrome). It may also be used for other conditions as determined by your doctor.
Omeprazole suspension is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced in the stomach.
Do NOT use omeprazole suspension if:
- you are allergic to any ingredient in omeprazole suspension or to any other PPI (eg, esomeprazole)
- you are taking clopidogrel, dasatinib, certain HIV protease inhibitors (eg, atazanavir, nelfinavir), rifampin, rilpivirine, or St. John's wort
Contact your doctor or health care provider right away if any of these apply to you.
Before using omeprazole suspension:
Some medical conditions may interact with omeprazole suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have low blood potassium or magnesium levels, low blood vitamin B12 levels or vitamin B12 deficiency, liver problems, or stomach or bowel cancer
- if you have osteoporosis (weak bones), a family history of osteoporosis, or other risk factors of osteoporosis (eg, smoking, poor nutrition)
Some MEDICINES MAY INTERACT with omeprazole suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood magnesium levels may be increased
- Voriconazole because it may increase the risk of omeprazole suspension's side effects
- Ginkgo biloba, rifampin, or St. John's wort because they may decrease omeprazole suspension's effectiveness
- Anticoagulants (eg, warfarin), benzodiazepines (eg, diazepam), cilostazol, citalopram, cyclosporine, digoxin, disulfiram, escitalopram, hydantoins (eg, phenytoin), methotrexate, saquinavir, or tacrolimus because the risk of their side effects may be increased by omeprazole suspension
- Ampicillins, azole antifungals (eg, ketoconazole), clopidogrel, certain HIV protease inhibitors (eg, atazanavir, nelfinavir), iron, mycophenolate, rilpivirine, or tyrosine kinase inhibitors (eg, dasatinib, erlotinib) because their effectiveness may be decreased by omeprazole suspension
This may not be a complete list of all interactions that may occur. Ask your health care provider if omeprazole suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use omeprazole suspension:
Use omeprazole suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take omeprazole suspension by mouth on an empty stomach before eating.
- Your pharmacist will prepare omeprazole suspension for you before you receive it. Contact your pharmacist if you have any questions.
- Shake well before each use.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- You may see small clumps of omeprazole suspension after it has been prepared. These clumps will disappear after a brief time.
- You may take antacids while you are taking omeprazole suspension if you are directed to do so by your doctor.
- Continue to take omeprazole suspension even if you feel well. Do not miss any doses.
- If you miss a dose of omeprazole suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use omeprazole suspension.
Important safety information:
- Omeprazole suspension may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use omeprazole suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
- Omeprazole suspension may increase the risk of hip, wrist, and spine fractures in patients with weak bones (osteoporosis). The risk may be greater if you take omeprazole suspension in high doses, for longer than a year, or if you are older than 50 years old. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Contact your doctor if you have any questions about this information.
- Low blood magnesium levels have been reported rarely in patients taking PPIs for at least 3 months. In most cases, this effect was seen after a year of treatment. If you will be taking omeprazole suspension for a long time, or if you take certain other medicines (eg, digoxin, diuretics), your doctor may perform lab tests to check for low blood magnesium levels. Seek medical attention right away if you experience symptoms of low blood magnesium levels (eg, dizziness; fast or irregular heartbeat; involuntary muscle movements; jitteriness or tremors; muscle aches, cramps, pain, spasms, or weakness; seizures).
- Long-term treatment (eg, longer than 3 years) with medicines like this one has rarely caused low vitamin B12 levels. Discuss any questions or concerns with your doctor.
- Check with your doctor to see whether you should take a calcium and vitamin D supplement while you take omeprazole suspension.
- Omeprazole suspension may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking omeprazole suspension.
- Omeprazole suspension should be used with caution in Asian patients; the risk of side effects may be increased in these patients.
- Use omeprazole suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially hip, wrist, and spine fractures.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking omeprazole suspension while you are pregnant. Omeprazole suspension is found in breast milk. Do not breast-feed while taking omeprazole suspension.
Possible side effects of omeprazole suspension:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; gas; headache; nausea; stomach pain; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; bone pain; chest pain; dark urine; fast, slow, or irregular heartbeat; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; severe diarrhea; severe stomach pain or cramps; swelling of the hands, ankles, or feet; symptoms of kidney problems (eg, not able to pass urine, change in the amount of urine produced, blood in the urine, a big weight gain); unusual bruising or bleeding; unusual tiredness; vision changes; yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of omeprazole suspension:
Store omeprazole suspension in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Keep omeprazole suspension out of the reach of children and away from pets.
- If you have any questions about omeprazole suspension, please talk with your doctor, pharmacist, or other health care provider.
- Omeprazole suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take omeprazole suspension or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about omeprazole suspension. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to omeprazole suspension. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using omeprazole suspension.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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