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Nuzyra (Omadacycline Injection)

Generic Name: Omadacycline Injection (oh MAD a SYE kleen)
Brand Name: Nuzyra

Medically reviewed by Drugs.com. Last updated on Jul 6, 2019.

Uses of Nuzyra:

  • It is used to treat bacterial infections.

What do I need to tell my doctor BEFORE I take Nuzyra?

  • If you have an allergy to Nuzyra (omadacycline injection) or any part of Nuzyra (omadacycline injection).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are taking any of these drugs: Acitretin, isotretinoin, or a penicillin.
  • If you are breast-feeding. Do not breast-feed for at least 4 days after using Nuzyra (omadacycline injection).

This is not a list of all drugs or health problems that interact with Nuzyra (omadacycline injection).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Nuzyra (omadacycline injection) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Nuzyra?

For all patients taking Nuzyra (omadacycline injection):

  • Tell all of your health care providers that you take Nuzyra (omadacycline injection). This includes your doctors, nurses, pharmacists, and dentists.
  • In one study, a slightly higher number of deaths happened in people taking Nuzyra (omadacycline injection) compared to people taking another drug used to treat pneumonia. All people who died were older than 65 years of age and most had other health problems, as well. The cause of these deaths is not known. If you have questions, talk with your doctor.
  • Do not use longer than you have been told. A second infection may happen.
  • This medicine may make you sunburn more easily. Use care if you will be in the sun. Tell your doctor if you sunburn easily while taking this drug.
  • If you are 65 or older, use Nuzyra (omadacycline injection) with care. You could have more side effects.
  • This medicine may cause harm to an unborn baby. Women must use birth control while taking Nuzyra (omadacycline injection). If you get pregnant, call your doctor right away.

Children:

  • This medicine is not approved for use in children younger than 18 years of age. Talk with the doctor.
  • This medicine may cause a change in tooth color to yellow-gray-brown in children younger than 8 years old. If this change of tooth color happens, it will not go away. Talk with the doctor.

How is this medicine (Nuzyra) best taken?

Use Nuzyra (omadacycline injection) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as an infusion into a vein over a period of time.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
  • Signs of too much acid in the blood (acidosis) like confusion; fast breathing; fast heartbeat; a heartbeat that does not feel normal; very bad stomach pain, upset stomach, or throwing up; feeling very sleepy; shortness of breath; or feeling very tired or weak.
  • Not able to pass urine or change in how much urine is passed.
  • Diarrhea is common with antibiotics. Rarely, a severe form called C diff–associated diarrhea (CDAD) may happen. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen during or a few months after taking antibiotics. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools. Check with your doctor before treating diarrhea.
  • Raised pressure in the brain has happened with drugs like this one. Most of the time, this went back to normal after the drug was stopped. Sometimes, loss of eyesight happened and did not go away even after the drug was stopped. Call your doctor right away if you have a headache or eyesight problems like blurred eyesight, seeing double, or loss of eyesight.
  • Pain and irritation where Nuzyra (omadacycline injection) goes into the body.

What are some other side effects of Nuzyra?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Upset stomach or throwing up.
  • Diarrhea.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Nuzyra?

  • If you need to store Nuzyra (omadacycline injection) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Nuzyra (omadacycline injection), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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