Generic Name: Posaconazole Injection (poe sa KON a zole)
Brand Name: Noxafil
Medically reviewed by Drugs.com. Last updated on Mar 20, 2019.
Uses of Noxafil:
- It is used to prevent fungal infections.
What do I need to tell my doctor BEFORE I take Noxafil?
- If you have an allergy to posaconazole or any other part of Noxafil (posaconazole injection).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have kidney disease.
- If you have any of these health problems: Low calcium levels, low magnesium levels, or low potassium levels.
- If you are taking any of these drugs: Atorvastatin, dihydroergotamine, ergonovine, ergotamine, lovastatin, methylergonovine, phenytoin, pimozide, quinidine, rifabutin, simvastatin, or sirolimus.
- If you are breast-feeding or plan to breast-feed.
- If the patient is a child. Do not give Noxafil (posaconazole injection) to a child.
This is not a list of all drugs or health problems that interact with Noxafil (posaconazole injection).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Noxafil (posaconazole injection) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Noxafil?
- Tell all of your health care providers that you take Noxafil (posaconazole injection). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Do not use longer than you have been told. A second infection may happen.
- Do not switch between different forms of Noxafil (posaconazole injection) without first talking with the doctor.
- This medicine interacts with many other drugs. The chance of side effects may be raised or how well Noxafil (posaconazole injection) works may be lowered. Check with your doctor and pharmacist to make sure that it is safe for you to take Noxafil (posaconazole injection) with all of your other drugs (prescription or OTC, natural products, vitamins).
- If you are taking vinblastine, vincristine, or vinorelbine, talk with your doctor. Very bad nerve problems like seizures; burning, numbness, and tingling; and a type of bowel block have happened when Noxafil (posaconazole injection) was used with vincristine.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Noxafil (posaconazole injection) while you are pregnant.
How is this medicine (Noxafil) best taken?
Use Noxafil (posaconazole injection) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Shortness of breath.
- Swelling in the arms or legs.
- Fever or chills.
- Sore throat.
- Any unexplained bruising or bleeding.
- Vaginal bleeding that is not normal.
- Feeling very tired or weak.
- A type of abnormal heartbeat (prolonged QT interval) has happened with Noxafil (posaconazole injection). Sometimes, this has led to another type of unsafe abnormal heartbeat (torsades de pointes). Call your doctor right away if you have a fast or abnormal heartbeat, or if you pass out.
- Very bad and sometimes deadly liver problems have happened with Noxafil (posaconazole injection). Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
What are some other side effects of Noxafil?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Stomach pain or diarrhea.
- Upset stomach or throwing up.
- Not hungry.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Noxafil?
- If you need to store Noxafil (posaconazole injection) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Noxafil (posaconazole injection), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Noxafil (posaconazole)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: azole antifungals
- FDA Alerts (1)
- FDA Approval History
- Noxafil (Posaconazole Delayed-Release Tablets)
- Noxafil (Posaconazole Oral Suspension)
- Noxafil (Advanced Reading)
- Noxafil Intravenous (Advanced Reading)