Generic Name: tbo-filgrastim (TBO-fil-GRA-stim)
Brand Name: Granix
Neutroval is used for:
Decreasing the amount of time that the number of certain white blood cells (neutrophils) are very low. It is used in certain cancer patients who are receiving chemotherapy. It may also be used for other conditions as determined by your doctor.
Neutroval is a hematopoietic agent. It works by stimulating the production of neutrophils by bone marrow.
Do NOT use Neutroval if:
- you are allergic to any ingredient in Neutroval, to filgrastim, or to pegfilgrastim
Contact your doctor or health care provider right away if any of these apply to you.
Before using Neutroval:
Some medical conditions may interact with Neutroval. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are able to become pregnant
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you are receiving radiation therapy
- if you have leukemia, sickle cell anemia, or other blood disorders (eg, myelodysplastic syndrome)
- if you have kidney or liver problems, spleen problems, lung or breathing problems, or a blood or tissue infection
Some MEDICINES MAY INTERACT with Neutroval. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Lithium because it may increase the risk of Neutroval's side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if Neutroval may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Neutroval:
Use Neutroval as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Neutroval. Talk to your pharmacist if you have questions about this information.
- Do not shake Neutroval. Shaking may damage Neutroval. If the syringe has been shaken, the solution may appear foamy and should not be used.
- Neutroval is usually given at your doctor's office, hospital, or clinic. If you will be using Neutroval at home, a health care provider will teach you how to use it. Be sure you understand how to use Neutroval. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into muscle or a vein.
- Before giving the injection, let it come to room temperature for 30 minutes. Do not heat Neutroval.
- Your first dose of Neutroval will be given at least 24 hours after you receive your chemotherapy. Do not use Neutroval within 24 hours before any chemotherapy treatment.
- Do not use Neutroval if it contains particles, is cloudy or discolored, or if the syringe is cracked or damaged.
- Use only the provided syringe and needle. Use the syringe and needle only 1 time. Dispose of them in a puncture-proof container as instructed by your health care provider.
- Choose a new site each time you inject Neutroval. Do not inject into an area that is tender, red, bruised, hard, swollen, or has scars or stretch marks.
- Discard any unused portion of medicine left in the syringe.
- Continue to use Neutroval for the full course of treatment. Do not miss any doses.
- Neutroval works best if it is used at the same time each day.
- If you get Neutroval on your skin, wash the area with soap and water.
- If you get Neutroval in your eyes, flush your eyes with water and call your doctor right away.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Neutroval, call your doctor to find out what to do.
Ask your health care provider any questions you may have about how to use Neutroval.
Important safety information:
- Tell your doctor or dentist that you take Neutroval before you receive any medical or dental care, emergency care, or surgery.
- Neutroval may reduce the chance of infection, but it does not prevent all infections. Contact your doctor right away if you develop signs of an infection (eg, fever; chills; sore throat; diarrhea; pain, redness, or swelling around a cut or sore).
- You may experience bone aches while you use Neutroval. These symptoms can usually be relieved by a non-aspirin pain reliever (eg, acetaminophen; nonsteroidal anti-inflammatory drugs [NSAIDs] such as ibuprofen) as directed by your doctor.
- Serious and sometimes fatal spleen problems (including spleen rupture) have been reported in patients using Neutroval. Contact your doctor right away if pain occurs in the stomach (especially in the left upper stomach area) or left shoulder area.
- A serious lung problem called acute respiratory distress syndrome (ARDS) has been reported in patients who use Neutroval. Contact your doctor if you have shortness of breath or trouble breathing after receiving Neutroval.
- Neutroval may interfere with certain lab tests, including certain bone scans or tests. Be sure your doctor and lab personnel know you are taking Neutroval.
- Lab tests, including complete blood cell counts, may be performed while you use Neutroval. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- PREGNANCY and BREAST-FEEDING: Neutroval may cause harm to the fetus. Do not become pregnant while you are using Neutroval. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Neutroval while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use Neutroval, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Neutroval:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Mild bone pain.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, eyes, or tongue; dizziness; fast heartbeat; sudden increased sweating); fainting; fast breathing; fever; left shoulder pain; severe or persistent bone pain; shortness of breath; stomach pain (especially in the left upper stomach area); swelling; trouble breathing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Neutroval:
Store Neutroval in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Neutroval may be stored at room temperature for up to 5 days. If not used within 5 days of being stored at room temperature, you can return Neutroval to the refrigerator. Do not do this more than 1 time. If stored at room temperature for more than 5 days, throw Neutroval away. Store the syringes in the carton to protect from light. Keep Neutroval out of the reach of children and away from pets.
- If you have any questions about Neutroval, please talk with your doctor, pharmacist, or other health care provider.
- Neutroval is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Neutroval or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Neutroval. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Neutroval. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Neutroval.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about tbo-filgrastim
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Other brands: Granix