Generic Name: pegfilgrastim (PEG-fil-GRA-stim)
Brand Name: Neulasta
Neulasta is used for:
Decreasing the incidence of infection in certain cancer patients undergoing myelosuppressive cancer treatments.
Neulasta is an amino acid. It works by stimulating bone marrow to produce white blood cells, which fight infection.
Do NOT use Neulasta if:
- you are allergic to any ingredient in Neulasta, filgrastim, or Escherichia coli-derived proteins
Contact your doctor or health care provider right away if any of these apply to you.
Before using Neulasta:
Some medical conditions may interact with Neulasta. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances (eg, latex, acrylics)
- if you have other blood problems (eg, sickle cell anemia), bone marrow leukemia, spleen problems, lung or breathing problems, or a blood or tissue infection
- if you are or will be undergoing chemotherapy or radiation therapy
Some MEDICINES MAY INTERACT with Neulasta. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Lithium because it may increase the risk of Neulasta's side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if Neulasta may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Neulasta:
Use Neulasta as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Neulasta. Talk to your pharmacist if you have questions about this information.
- Neulasta is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Neulasta at home, a health care provider will teach you how to use it. Be sure you understand how to use Neulasta. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Do not shake Neulasta.
- Do not use Neulasta if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Neulasta, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Neulasta.
Important safety information:
- Tell your doctor or dentist that you take Neulasta before you receive any medical or dental care, emergency care, or surgery.
- Serious and sometimes fatal spleen problems (including spleen rupture) have been reported in patients using Neulasta. Notify your doctor immediately if you experience left-sided upper stomach pain and/or shoulder tip pain.
- Neulasta may reduce the chance of infection, but it does not prevent all infection. Tell your doctor right away if you notice symptoms of infection (eg, fever; chills; sore throat; diarrhea; redness, swelling, or pain around a cut or sore) while you take Neulasta.
- Some people with sickle cell disease have had times where the sickle cell disease has gotten worse when taking this drug. Sometimes, this has been fatal. Talk with the doctor.
- Tell your doctor if you develop a lump, swelling, or bruising at the injection site that does not go away.
- Neulasta may cause a serious and sometimes fatal problem called capillary leak syndrome (CLS). CLS may lead to low blood pressure and harm to the organs. It may also lead to bleeding or lower blood flow in the stomach or bowel, chest pain or pressure, confusion, heart attack, irregular heartbeat, kidney problems, lung or breathing problems, or swelling. Discuss any questions of concerns with your doctor.
- If you are using the On-Body Injector: Do not travel, drive, or do other tasks or actions that require alertness during hours 26 through 29 after the Injector is put on. Be sure you understand how the injector works, what tasks and actions to avoid, and when to avoid them. Be sure you know how to tell if all of the drug has been given, or if there has been a problem with the injector. Talk with your doctor.
- Lab tests may be performed while you use Neulasta. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Neulasta while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use Neulasta, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Neulasta:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Bone or joint pain; constipation; muscle pain.
Severe allergic reactions (rash; hives; itching; difficulty breathing; dizziness; fast heartbeat; increased sweating; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); change in how much urine is passed; fainting; fast breathing; feeling full; fever; left-sided shoulder tip pain; left-sided upper stomach pain; lump, swelling, or bruising at the injection site; severe or persistent bone, chest, joint, or stomach pain; shortness of breath; swelling (eg, of your stomach): unusual tiredness or weakness; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Neulasta:
Store Neulasta in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C), and in the original carton. Do not freeze. If accidentally frozen, allow the medicine to thaw in the refrigerator. If frozen more than once, the medicine should be thrown away. If Neulasta is left at room temperature for more than 48 hours, it should be discarded. Protect from light. Keep Neulasta, as well as needles and syringes, out of the reach of children and away from pets.
- If you have any questions about Neulasta, please talk with your doctor, pharmacist, or other health care provider.
- Neulasta is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Neulasta or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Neulasta. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Neulasta. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Neulasta.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.