Generic Name: Mipomersen (mi poe MER sen)
Brand Name: Kynamro
- This medicine may cause liver problems in some patients. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You can only get mipomersen through the Kynamro REMS Program.
Uses of Mipomersen:
- It is used to lower cholesterol.
What do I need to tell my doctor BEFORE I take Mipomersen?
- If you have an allergy to mipomersen or any other part of this medicine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have liver disease.
This is not a list of all drugs or health problems that interact with mipomersen.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Mipomersen?
- Tell all of your health care providers that you take mipomersen. This includes your doctors, nurses, pharmacists, and dentists.
- Talk with your doctor before you drink alcohol.
- If you are 65 or older, use this medicine with care. You could have more side effects.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- Use birth control that you can trust to prevent pregnancy while taking mipomersen.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Mipomersen) best taken?
Use mipomersen as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Keep taking this medicine as you have been told by your doctor or other health care provider, even if you feel well.
- To gain the most benefit, do not miss doses.
- It is given as a shot into the fatty part of the skin.
- Your doctor may teach you how to give the shot.
- Follow how to use carefully.
- Before giving the shot, let it come to room temperature. Do not heat mipomersen.
- Give on the same day each week.
- Give this medicine into clean, dry, healthy skin on the belly, upper leg, or upper arm.
- Do not give into red or irritated skin.
- Do not give into skin that is tattooed or scarred.
- Wash your hands before and after use.
- Move the site where you give the shot with each shot.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- If it is 3 or more days to the time of your next dose, take the missed dose as soon as you think about it and go back to your normal day.
- If it is 1 or 2 days to the time of your next dose, skip the missed dose and go back to your normal day.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Chest pain.
- A heartbeat that does not feel normal.
- Swelling in the arms or legs.
- Very bad headache.
- Very bad irritation where the shot was given.
What are some other side effects of Mipomersen?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach.
- Feeling tired or weak.
- Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating.
- Irritation or swelling where the shot was given.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Mipomersen?
- Store in a refrigerator. Do not freeze.
- Protect from light.
- This medicine may be stored at room temperature for up to 2 weeks before use.
- Protect from heat.
- Throw away any part not used after use.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time mipomersen is refilled. If you have any questions about this medicine, please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take mipomersen or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to mipomersen. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Review Date: October 4, 2017
More about mipomersen
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
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- Drug class: miscellaneous antihyperlipidemic agents
Other brands: Kynamro