Medroxyprogesterone injectable suspensionPronunciation
Generic Name: medroxyprogesterone (med-ROX-ee-proe-JES-ter-one)
Brand Name: Depo-Provera
Medroxyprogesterone injectable suspension may cause you to lose calcium from your bones. This could reduce bone strength. This effect is greater if you use medroxyprogesterone injectable suspension for a long time. Your bones may not recover completely after you stop using it. If you use medroxyprogesterone injectable suspension continuously for more than 2 years, you may have an increased risk for weak, porous bones (osteoporosis). This could increase the risk of broken bones, especially after menopause. It is not known if the risk of developing weak bones is greater in teenagers or young adults who use medroxyprogesterone injectable suspension.
Medroxyprogesterone injectable suspension should not be used as a long-term birth control method (longer than 2 years) unless other birth control methods are not right for you. Talk with your doctor for more information.
Medroxyprogesterone injectable suspension is used for:
Preventing pregnancy. It may also be used for certain conditions as determined by your doctor.
Medroxyprogesterone injectable suspension is a progestin hormone. It works by inhibiting chemicals released from the brain that normally stimulate the ovaries to produce eggs. It also alters the lining of the uterus so it is less likely to accept a fertilized egg. These effects work together to reduce the chance of pregnancy occurring after intercourse.
Do NOT use medroxyprogesterone injectable suspension if:
- you are allergic to any ingredient in medroxyprogesterone injectable suspension
- you have a history of bleeding in the brain or a stroke, brain blood vessel problems, breast cancer, liver problems, undiagnosed vaginal bleeding, or blood clots
- you are pregnant or think you may be pregnant
Contact your doctor or health care provider right away if any of these apply to you.
Before using medroxyprogesterone injectable suspension:
Some medical conditions may interact with medroxyprogesterone injectable suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of an abnormal mammogram, fibrocystic breast disease, lumps in the breast, bleeding from your nipples, kidney problems, heart problems (eg, congestive heart failure), high blood pressure, menstrual changes (eg, irregular or lighter periods), migraine headaches, asthma, seizures, diabetes, or mental or mood problems (eg, depression)
- if you have a family history of breast cancer
- if you have bone problems (eg, weak bones, osteoporosis), a certain eating disorder (anorexia nervosa), or if a family member has had bone problems (eg, osteoporosis)
- if you drink alcohol or use tobacco regularly
- if you are taking medicines that can weaken the bones, such as anticonvulsants (eg, phenytoin) or corticosteroids (eg, prednisone)
Some MEDICINES MAY INTERACT with medroxyprogesterone injectable suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Aprepitant, barbiturates (eg, phenobarbital), bosentan, carbamazepine, felbamate, griseofulvin, HIV protease inhibitors (eg, ritonavir), nonnucleoside reverse transcriptase inhibitors (NNRTIs) (eg, nevirapine), oxcarbazepine, phenytoin, rifamycins (eg, rifampin), St. John's wort, or topiramate because they may decrease medroxyprogesterone injectable suspension's effectiveness and side effects, and menstrual irregularities (spotting, breakthrough bleeding) and/or pregnancy may occur. You will need to use another form of birth control (eg, condoms) if you take any of these medicines while using medroxyprogesterone injectable suspension
This may not be a complete list of all interactions that may occur. Ask your health care provider if medroxyprogesterone injectable suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use medroxyprogesterone injectable suspension:
Use medroxyprogesterone injectable suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with medroxyprogesterone injectable suspension. Talk to your pharmacist if you have questions about this information.
- Medroxyprogesterone injectable suspension is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using medroxyprogesterone injectable suspension at home, a health care provider will teach you how to use it. Be sure you understand how to use medroxyprogesterone injectable suspension. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Do not use medroxyprogesterone injectable suspension if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Be sure you know when you should begin using medroxyprogesterone injectable suspension according to your doctor's instructions. Discuss any questions or concerns with your doctor.
- Medroxyprogesterone injectable suspension is given every 3 months. It is very important that you return to your doctor's office for your next injection promptly at the end of the 3-month interval.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of medroxyprogesterone injectable suspension, contact your doctor right away.
Ask your health care provider any questions you may have about how to use medroxyprogesterone injectable suspension.
Important safety information:
- Medroxyprogesterone injectable suspension may cause drowsiness, dizziness, light-headedness, or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use medroxyprogesterone injectable suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Medroxyprogesterone injectable suspension may cause dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or protective clothing when exposed to the sun, sunlamps, or tanning booths.
- Medroxyprogesterone injectable suspension may cause a decrease in the amount of calcium in your bones and make your bones weaker. This effect is of most concern during adolescence (teenage years) and early adulthood. If you need to use medroxyprogesterone injectable suspension as a long-term birth control method (more than 2 years), your health care provider may test you for weak bones. Discuss any questions or concerns with your doctor.
- Check with your doctor to see whether you should take a calcium and vitamin D supplement while you use medroxyprogesterone injectable suspension.
- You may experience menstrual cycle changes while using medroxyprogesterone injectable suspension, including irregular or unpredictable bleeding or spotting, or an increase or decrease in menstrual bleeding. Contact your doctor right away if you experience unusually heavy or continuous bleeding, or any other severe or persistent menstrual changes.
- You may skip a menstrual period or your menstrual periods may stop completely while you use medroxyprogesterone injectable suspension. If you have been receiving medroxyprogesterone injectable suspension regularly every 3 months, you are probably not pregnant. However, if you think you may be pregnant, contact your doctor right away.
- Medroxyprogesterone injectable suspension may take time to wear off after your last dose. You may not be able to become pregnant for several months after stopping medroxyprogesterone injectable suspension. Discuss any questions or concerns with your doctor.
- Diabetes patients - Medroxyprogesterone injectable suspension may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Medroxyprogesterone injectable suspension does not stop the spread of HIV or sexually transmitted diseases (STDs) to others through blood or sexual contact. Use barrier methods of birth control (eg, condoms) if you have an HIV infection or an STD. Do not share needles, injection supplies, or items like toothbrushes or razors.
- Medroxyprogesterone injectable suspension may interfere with certain lab tests, including urinary steroid levels, gonadotropin and other hormone levels, thyroid function, blood clotting, liver function, and blood cholesterol. Be sure your doctor and lab personnel know you are using medroxyprogesterone injectable suspension.
- Lab tests, including bone density and blood pressure checks, may be performed while you use medroxyprogesterone injectable suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Medroxyprogesterone injectable suspension should not be used in CHILDREN who have not had their first menstrual period; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Do not use medroxyprogesterone injectable suspension if you are pregnant. If you think you may be pregnant, contact your doctor right away. Medroxyprogesterone injectable suspension is found in breast milk. If you are or will be breast-feeding while you use medroxyprogesterone injectable suspension, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of medroxyprogesterone injectable suspension:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Acne; breast pain or tenderness; changes in menstrual flow, including breakthrough bleeding, spotting, or missed periods; decreased sexual desire; dizziness; drowsiness; headache; hot flashes; leg cramps; nausea; nervousness; stomach pain or discomfort; tiredness; trouble sleeping; weakness; weight gain.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); breast lumps or nipple bleeding; burning, numbness, or tingling; calf or leg pain, swelling, or tenderness; chest pain; coughing up blood; dark urine; fast heartbeat; fever; mental or mood changes (eg, depression); pale stools; pain, pus, or bleeding at the injection site; partial or complete loss of vision or other changes in vision (eg, double vision); persistent loss of appetite; severe dizziness or fainting; severe stomach pain or tenderness; seizures; shortness of breath; slurred speech; sudden loss of coordination; sudden or severe headache or vomiting; swelling of the hands, ankles or feet; unusual tiredness or weakness; unusually heavy or persistent vaginal bleeding; weakness, numbness, or pain in the arms or legs; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of medroxyprogesterone injectable suspension:
Store medroxyprogesterone injectable suspension at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep medroxyprogesterone injectable suspension out of the reach of children and away from pets.
- If you have any questions about medroxyprogesterone injectable suspension, please talk with your doctor, pharmacist, or other health care provider.
- Medroxyprogesterone injectable suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take medroxyprogesterone injectable suspension or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about medroxyprogesterone injectable suspension. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to medroxyprogesterone injectable suspension. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using medroxyprogesterone injectable suspension.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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