Medically reviewed by Drugs.com. Last updated on Jan 5, 2021.
Uses of Mayzent Starter Pack:
- It is used to treat MS (multiple sclerosis).
What do I need to tell my doctor BEFORE I take Mayzent Starter Pack?
- If you are allergic to Mayzent Starter Pack (siponimod); any part of Mayzent Starter Pack (siponimod); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have any of these health problems: Brain blood vessel disease, high blood pressure, an infection, sleep apnea, or slow heartbeat.
- If you have ever had any of these health problems: Certain types of abnormal heartbeats (heart block, sick sinus syndrome, long QT on ECG), chest pain (angina), heart attack, heart failure, transient ischemic attack (TIA), or stroke.
- If you have had the varicella vaccine in the past month.
- If you have recently had a live vaccine
- If you have taken alemtuzumab.
- If you are taking any of these drugs: Efavirenz, fluconazole, or modafinil.
- If you are taking or have recently taken any drugs that can cause a slow heartbeat, a certain type of abnormal heartbeat (prolonged QT interval), or suppress your immune system. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
This is not a list of all drugs or health problems that interact with Mayzent Starter Pack (siponimod).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Mayzent Starter Pack (siponimod) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Mayzent Starter Pack?
- Tell all of your health care providers that you take Mayzent Starter Pack (siponimod). This includes your doctors, nurses, pharmacists, and dentists.
- You will need to be tested for a gene type called CYP2C9*3/*3 before starting Mayzent Starter Pack (siponimod). If you are not sure if you have been tested for this gene type, talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have an eye exam as you have been told by your doctor.
- If you have not had chickenpox or a chickenpox vaccine, talk with your doctor.
- Slow or abnormal heartbeat may happen with Mayzent Starter Pack (siponimod), especially after your first dose. People with certain heart problems will need to be watched closely for 6 hours after the first dose of Mayzent Starter Pack (siponimod). Before starting Mayzent Starter Pack (siponimod), tell your doctor about all of your other drugs and health problems. Call your doctor right away if you have dizziness, slow heartbeat or a heartbeat that does not feel normal, or tiredness.
- You will need an ECG before starting Mayzent Starter Pack (siponimod) and during treatment. Talk with your doctor.
- You may have more of a chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Some infections have been very bad and even deadly.
- Talk with your doctor before getting any vaccines while using Mayzent Starter Pack (siponimod) and for at least 4 weeks after stopping it. Use with Mayzent Starter Pack (siponimod) may either raise the chance of an infection or make the vaccine not work as well.
- High blood pressure has happened with Mayzent Starter Pack (siponimod). Have your blood pressure checked as you have been told by your doctor.
- When Mayzent Starter Pack (siponimod) is stopped, MS signs can come back and may be worse than before or during treatment. If you stop Mayzent Starter Pack (siponimod) and your MS signs get worse, call your doctor right away.
- Do not stop taking Mayzent Starter Pack (siponimod) without calling the doctor who ordered it for you.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- Use birth control to prevent pregnancy during treatment and for 10 days after your last dose.
- If you get pregnant while taking Mayzent Starter Pack (siponimod) or within 10 days after your last dose, call your doctor right away.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Mayzent Starter Pack) best taken?
Use Mayzent Starter Pack (siponimod) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- Keep taking Mayzent Starter Pack (siponimod) as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of meningitis like headache with fever, stiff neck, upset stomach, confusion, or if lights bother the eyes.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Shortness of breath.
- Trouble breathing that is new or worse.
- Change in eyesight.
- Swelling in the arms or legs.
- A very bad and sometimes deadly brain problem called posterior reversible encephalopathy syndrome (PRES) has happened with Mayzent Starter Pack (siponimod). Call your doctor right away if you have signs like feeling confused, lowered alertness, change in eyesight, loss of eyesight, seizures, or very bad headache.
- A very bad brain problem called progressive multifocal leukoencephalopathy (PML) may happen with Mayzent Starter Pack (siponimod). It may cause disability or can be deadly. Tell your doctor right away if you have signs like confusion, memory problems, low mood (depression), change in the way you act, change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or change in eyesight.
What are some other side effects of Mayzent Starter Pack?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach.
- Pain in arms or legs.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Mayzent Starter Pack?
- Store unopened containers in a refrigerator. Do not freeze.
- After opening, store at room temperature.
- Store in original container.
- Be sure you know how long you can store Mayzent Starter Pack (siponimod) before you need to throw it away.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Mayzent Starter Pack (siponimod) is refilled. If you have any questions about Mayzent Starter Pack (siponimod), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
- How much does Mayzent cost?
- How does Mayzent work?
- How long do you take Mayzent for?
- Vumerity vs Mayzent - what's the difference?
- Can people with end stage renal disease take Mayzent?
- What are the new drugs used for multiple sclerosis (MS)?
More about Mayzent (siponimod)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Imprints, Shape & Color Data
- Drug Interactions
- Pricing & Coupons
- 4 Reviews
- Drug class: selective immunosuppressants
- FDA Approval History
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.